Anticoagulation in patients with heparin-induced thrombocytopenia type II

Seminars in Thrombosis and Hemostasis

Volumn 23, Issue 2, 1997, Pages 189-196

  Harenberg, Job ^a   Huhle, Günter ^a   Piazolo, Lukas ^a   Wang, Lianchun U ^a   Heene, Dieter L ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Heparin induced thrombocytopenia; Heparinoid; r Hirudin; Thromboembolism

Indexed keywords

DALTEPARIN; DANAPAROID; HEPARIN; HEPARINOID; IMMUNOGLOBULIN; LEPIRUDIN; LOW MOLECULAR WEIGHT HEPARIN; MONOEMBOLEX; NADROPARIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; THROMBOCYTOPENIA; THROMBOSIS;

EID: 0030958446     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-996090     Document Type: Article

References (20)

1. Ansell J, D Deykin: Heparin-induced thrombocvtopenia and recurrent thromboembolism. Am J Hematol 8:325-332, 1980.
2. Warkentin T. MN Levine, J Hirsh, P Horsewood, RS Roberts, M Gent, JG Kelton: Heparin-induced thrombocytopenia in patients treated with low molecular weight heparin or unfractionated heparin. N Engl J Med 332:1330-1335, 1995.
3. Rhodes G, R Dicon, D Silber: Heparin-induced thrombocylopenia with thrombotic and hemorrhagic manifestations. Surg Gynecol Obstet 136:409-416, 1973.
4. Denton J, DA Lane, L Thunberg, AM Slater, U Lindahl: Binding of platelet factor 4 to heparin oligosaccharides. Biochem J 209: 455-460, 1983.
5. Amiral J, F Bridey, M Dreyfus, AM Vissac, E Fressinaud, M Wolf, D Meyer: PF 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Development of a diagnostic test. Thromb Haemostas 68:95-96 (Letter), 1992.
6. Greinacher A, B Pötsch, J Amiral, V Dummel, A Eichner, C Mueller-Eckhardt: Heparin-associated thrombocytopenia: Isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen. Thromb Haemostas 71:247-251, 1994.
7. Visentin G, S Ford, J Scott, R Aster: Antibodies from patients with heparin-induced thrombocytopenia thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells. J Clin Invest 93:81-88, 1994.
8. Greinacher A, I Michels, U Liebenhoff, P Presek, C Mueller-Eckhardt: Heparin-associated thrombocytopenia; immune complexes are attached to the platelet membrane by the negative charge of highly sulphated oligosaccharides: Br J Haematol 84: 711-716. 1993.
9. Harenberg J, R Zimmermann, F Schwarz, W Kühler: Treatment of heparin-induced thrombocytopenia with thrombosis by a new heparinoid. Lancet 1:986-987, 1983.
10. Magnani HN: Heparin-induced thrombocytopenia (HIT): An overview of 230 patients treated with Orgaran (Org 10172). Thromb Haemostas 70:554-561, 1993.
11. Greinacher A, S Alban, V Dummel, F Franz, C Mueller-Eckhardt: Characterization of the structural requirements for a carbohydrate based anticoagulant with a reduced risk of inducing the immunologic type of heparin associated thrombocytopenia. Thromb Haemostas 74:886-892, 1995.
12. Baumann MA, JK Menotive, RH Aster, T Andersen: Urgent treatment of idiopathic thrombocytopenic purpura with single-dose gamma globulin infusion followed by platelet transfusion. Ann Intern Med 104:808-809, 1986.
13. Bussel JB, I Schulman, MW Hilgartner, S Barandum: Intravenous use of gamma globulin in the treatment of chronic idiopathic thrombocytopenic purpura as a means to defer splenectomy. J Pediatr 103:651-654, 1983.
14. Frame JN, KP Mulvey, JC Phares, MC Anderson: Correction of severe heparin-associated thrombocytopenia with intravenous immunoglobulin. Ann Intern Med 111:946-947, 1989.
15. Kelton JG, JW Smith, TH Warkentin, C Hayward, G Denomme, P Horsewood: Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4. Blood 83:3232-3239, 1994.
16. Greinacher A, S Alban, V Dummel, G Franz, C Mueller-Eckhardt: Characterization of the structural requirements for a carbohydrate based anticoagulant with a reduced risk of inducing the immunologicul type of hepurin associated thrombocytopenia. Thromb Haemostas 74:886-892, 1995.
17. Lewis BE, JM Walenga, DB Wallis: Anticoagulation with Novastan® (argatroban) in patients with heparin-induced thrombocytopenia and heparin-induced thrombocytopenia and thrombosis syndrome. Semin Thromb Hemostas 23:197-202, 1997.
18. Arnout J, B Spitz, C Wittevrongel, M Vanrusset, A Van Assche, J Vermylen: High-dose intravenous immunoglobulin treatment of a pregnant patient with an antiphospholipid syndrome: Immunological changes associated with a successful outcome. Thromb Haemostas 71:741-747, 1994.
19. Harenberg J, F Schulze, H Sheikh, R Zimmermann, H Mörl, E Weber: Allergische Hautreaktionen auf Heparin. Phlebol Proktol 11:195-196, 1982.
20. Schiele F, A Vuillemenot, P Kramarz, Y Keiffer, T Anguenot, Y Bernard, JP Bassand: Use of recombinant hirudin as antithrombotic treatment in patients with heparin-induced thrombocytopenia. Am J Hematol 50:20-25, 1995.