-
1
-
-
0019142171
-
The presence of the type a form of monoamine oxidase within nigrostriatal dopamine-containing neurons
-
Demarest K, Smith D, Azzaro A. The presence of the type A form of monoamine oxidase within nigrostriatal dopamine-containing neurons. J Pharmacol Exp Ther 1980; 215: 461-8
-
(1980)
J Pharmacol Exp Ther
, vol.215
, pp. 461-468
-
-
Demarest, K.1
Smith, D.2
Azzaro, A.3
-
2
-
-
0029951445
-
Does monoamine oxidase type B play a role in dopaminergic nerve cell death in Parkinson's disease?
-
Damier P, Kastner A, Agid Y, et al. Does monoamine oxidase type B play a role in dopaminergic nerve cell death in Parkinson's disease? Neurology 1996; 46: 1262-9
-
(1996)
Neurology
, vol.46
, pp. 1262-1269
-
-
Damier, P.1
Kastner, A.2
Agid, Y.3
-
3
-
-
0343018791
-
Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons
-
Levitt P, Pintar J, Breakfield X. Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons. Proc Natl Acad Sci USA 1982; 79: 6385-9
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 6385-6389
-
-
Levitt, P.1
Pintar, J.2
Breakfield, X.3
-
4
-
-
0021276089
-
Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase
-
Chiba K, Trevor AJ, Castagnoli Jr N. Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase. Biochem Biophys Res Commun 1984; 120: 574-8
-
(1984)
Biochem Biophys Res Commun
, vol.120
, pp. 574-578
-
-
Chiba, K.1
Trevor, A.J.2
Castagnoli Jr., N.3
-
5
-
-
0021224694
-
Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors
-
Heikkila RE, Manzino L, Cabbat FS, et al. Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors. Nature 1984; 311: 467-9
-
(1984)
Nature
, vol.311
, pp. 467-469
-
-
Heikkila, R.E.1
Manzino, L.2
Cabbat, F.S.3
-
6
-
-
0027530638
-
Effect of tocopherol and deprenyl on the progression of disability in early Parkinson's disease
-
Parkinson Study Group. Effect of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med 1993; 328: 176-83
-
(1993)
N Engl J Med
, vol.328
, pp. 176-183
-
-
-
7
-
-
0030042620
-
Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP subjects not requiring levodopa
-
Parkinson Study Group. Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP subjects not requiring levodopa. Ann Neurol 1996; 39: 29-36
-
(1996)
Ann Neurol
, vol.39
, pp. 29-36
-
-
-
8
-
-
0028858370
-
The effect of deprenyl and levodopa on the progression of Parkinson's disease
-
Olanow CW, Hauser RA, Gauger L, et al. The effect of deprenyl and levodopa on the progression of Parkinson's disease. Ann Neurol 1995; 38: 771-7
-
(1995)
Ann Neurol
, vol.38
, pp. 771-777
-
-
Olanow, C.W.1
Hauser, R.A.2
Gauger, L.3
-
9
-
-
9044227267
-
Comparison of therapeutic effects and mortality data of levodopa and levodopa combined with selegiline in patients with early, mild Parkinson's disease
-
Lees AJ, Parkinson's Disease Research Group of the United Kingdom. Comparison of therapeutic effects and mortality data of levodopa and levodopa combined with selegiline in patients with early, mild Parkinson's disease. BMJ 1995; 311: 1602-7
-
(1995)
BMJ
, vol.311
, pp. 1602-1607
-
-
Lees, A.J.1
-
10
-
-
0027317825
-
Comparison of therapeutic effects of levodopa, levodopa and selegiline, and bromocriptine in patients with early, mild Parkinson's disease: Three-year interim report
-
Parkinson's Disease Research Group in the United Kingdom. Comparison of therapeutic effects of levodopa, levodopa and selegiline, and bromocriptine in patients with early, mild Parkinson's disease: three-year interim report. BMJ 1993; 307: 469-72
-
(1993)
BMJ
, vol.307
, pp. 469-472
-
-
-
11
-
-
0029916818
-
Effect of adding selegiline to levodopa in early, mild Parkinson's disease. Other studies have not shown increased mortality
-
Mäki-Ikola O, Kilkku O, Heinonen E. Effect of adding selegiline to levodopa in early, mild Parkinson's disease. Other studies have not shown increased mortality [letter]. BMJ 1996; 312: 702
-
(1996)
BMJ
, vol.312
, pp. 702
-
-
Mäki-Ikola, O.1
Kilkku, O.2
Heinonen, E.3
-
12
-
-
85007737830
-
Stopping selegiline may lead to problems for patients
-
Anderson KE, Girdwood AC, Wilson JA. Stopping selegiline may lead to problems for patients [letter]. BMJ 1996; 312: 702
-
(1996)
BMJ
, vol.312
, pp. 702
-
-
Anderson, K.E.1
Girdwood, A.C.2
Wilson, J.A.3
-
13
-
-
85007772141
-
Patients taking selegiline may have received more levodopa than necessary
-
Olanow CW, Goodbold JH, Koller W. Patients taking selegiline may have received more levodopa than necessary [letter]. BMJ 1996; 312: 702-3
-
(1996)
BMJ
, vol.312
, pp. 702-703
-
-
Olanow, C.W.1
Goodbold, J.H.2
Koller, W.3
-
14
-
-
8544230113
-
Selegiline is effective and safe in early stages
-
MacMahon DG, Bland R. Selegiline is effective and safe in early stages [letter]. BMJ 1996; 312: 703
-
(1996)
BMJ
, vol.312
, pp. 703
-
-
MacMahon, D.G.1
Bland, R.2
-
15
-
-
0030589945
-
Parkinson's disease is rarely a primary cause of death
-
Silva MT, Watts PM, Jenner P. Parkinson's disease is rarely a primary cause of death [letter]. BMJ 1996; 312: 703
-
(1996)
BMJ
, vol.312
, pp. 703
-
-
Silva, M.T.1
Watts, P.M.2
Jenner, P.3
-
16
-
-
85047694873
-
Selegiline may be toxic in presence of increased dopamine concentrations
-
Yu PH, Lai CT, Boulton AA. Selegiline may be toxic in presence of increased dopamine concentrations [letter]. BMJ 1996; 312: 703-4
-
(1996)
BMJ
, vol.312
, pp. 703-704
-
-
Yu, P.H.1
Lai, C.T.2
Boulton, A.A.3
-
17
-
-
0030589922
-
'On treatment' rather than intention to treat analysis should have been used
-
Gerlach M, Riederer P, Vogt H. 'On treatment' rather than intention to treat analysis should have been used [letter]. BMJ 1996; 312: 704
-
(1996)
BMJ
, vol.312
, pp. 704
-
-
Gerlach, M.1
Riederer, P.2
Vogt, H.3
-
18
-
-
0030589944
-
Causes of death need confirmation
-
Jellinger KA. Causes of death need confirmation [letter]. BMJ 1996; 312: 704
-
(1996)
BMJ
, vol.312
, pp. 704
-
-
Jellinger, K.A.1
-
19
-
-
0026531427
-
Neurotoxicity of levodopa on catecholamine-rich neurons
-
Mena MA, Pardo B, Casarejos MJ, et al. Neurotoxicity of levodopa on catecholamine-rich neurons. Mov Disorders 1992; 7: 23-31
-
(1992)
Mov Disorders
, vol.7
, pp. 23-31
-
-
Mena, M.A.1
Pardo, B.2
Casarejos, M.J.3
-
20
-
-
0028081018
-
Intense oxidative DNA damage promoted by L-DOPA and its metabolites: Implications for neurodegenerative disease
-
Spencer JPE, Jenner A, Aruoma OJ, et al. Intense oxidative DNA damage promoted by L-DOPA and its metabolites: implications for neurodegenerative disease. FEBS Lett 1994; 353: 246-50
-
(1994)
FEBS Lett
, vol.353
, pp. 246-250
-
-
Spencer, J.P.E.1
Jenner, A.2
Aruoma, O.J.3
-
21
-
-
0026773348
-
Combined histochemical and biochemical demonstration of nigral vulnerability to lipid peroxidation induced by DOPA and iron
-
Tanaka M, Sotomatsu A, Kanai H, et al. Combined histochemical and biochemical demonstration of nigral vulnerability to lipid peroxidation induced by DOPA and iron. Neurosci Lett 1992; 140: 42-6
-
(1992)
Neurosci Lett
, vol.140
, pp. 42-46
-
-
Tanaka, M.1
Sotomatsu, A.2
Kanai, H.3
-
22
-
-
0020989520
-
Parkinsonism treated with levodopa: Progression and mortality
-
Hoehn MM. Parkinsonism treated with levodopa: progression and mortality. J Neural Transm 1983; Suppl. 19: 253-64
-
(1983)
J Neural Transm
, Issue.19 SUPPL.
, pp. 253-264
-
-
Hoehn, M.M.1
-
23
-
-
0023226021
-
Multi-center study of Parkinson mortality with early versus later dopa treatment
-
Diamond SG, Markham CH, Hoehn MM, et al. Multi-center study of Parkinson mortality with early versus later dopa treatment. Ann Neurol 1987; 22: 8-12
-
(1987)
Ann Neurol
, vol.22
, pp. 8-12
-
-
Diamond, S.G.1
Markham, C.H.2
Hoehn, M.M.3
-
24
-
-
0025265733
-
Mortality associated with early and late levodopa therapy initiation in Parkinson's disease
-
Scigliano G, Musicco M, Soliveri P, et al. Mortality associated with early and late levodopa therapy initiation in Parkinson's disease. Neurology 1990; 40: 265-9
-
(1990)
Neurology
, vol.40
, pp. 265-269
-
-
Scigliano, G.1
Musicco, M.2
Soliveri, P.3
-
25
-
-
0027362832
-
Toxic and protective effects of L-DOPA on mesencephalic cell cultures
-
Mytilineou C, Han SK, Cohen G. Toxic and protective effects of L-DOPA on mesencephalic cell cultures. J Neurochem 1993; 61: 1470-8
-
(1993)
J Neurochem
, vol.61
, pp. 1470-1478
-
-
Mytilineou, C.1
Han, S.K.2
Cohen, G.3
-
26
-
-
0030059868
-
L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress
-
Han SK, Mytilineou C, Cohen G. L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress. J Neurochem 1996; 66: 501-10
-
(1996)
J Neurochem
, vol.66
, pp. 501-510
-
-
Han, S.K.1
Mytilineou, C.2
Cohen, G.3
-
28
-
-
0017729733
-
Deprenyl in Parkinson's disease
-
Lees AJ, Shaw KM, Kohoul LJ, et al. Deprenyl in Parkinson's disease. Lancet 1977; 11: 791-5
-
(1977)
Lancet
, vol.11
, pp. 791-795
-
-
Lees, A.J.1
Shaw, K.M.2
Kohoul, L.J.3
-
29
-
-
0018127577
-
L-Deprenyl treatment of on-off phenomena in Parkinson's disease
-
Rinne UK, Siirtola T, Sonninen V. L-Deprenyl treatment of on-off phenomena in Parkinson's disease. J Neural Transm 1978; 43: 253-62
-
(1978)
J Neural Transm
, vol.43
, pp. 253-262
-
-
Rinne, U.K.1
Siirtola, T.2
Sonninen, V.3
-
30
-
-
0019124920
-
Deprenyl in the management of response fluctuations in patients with Parkinson's disease on levodopa
-
Schachter M, Marsden CD, Parkes JD. Deprenyl in the management of response fluctuations in patients with Parkinson's disease on levodopa. J Neurol Neurosurg Psychiatry 1980; 43: 1016-21
-
(1980)
J Neurol Neurosurg Psychiatry
, vol.43
, pp. 1016-1021
-
-
Schachter, M.1
Marsden, C.D.2
Parkes, J.D.3
-
31
-
-
0021852048
-
The effect of L-deprenyl on on-off phenomena in Parkinson's disease
-
Brodersen P, Philbert A, Gulliksen G, et al. The effect of L-deprenyl on on-off phenomena in Parkinson's disease. Acta Neurol Scand 1985; 71: 494-7
-
(1985)
Acta Neurol Scand
, vol.71
, pp. 494-497
-
-
Brodersen, P.1
Philbert, A.2
Gulliksen, G.3
-
32
-
-
3242784708
-
Deprenyl in the treatment of symptom fluctuations in advanced Parkinson's disease
-
Golbe LI, Lieberman AN, Muenter MD, et al. Deprenyl in the treatment of symptom fluctuations in advanced Parkinson's disease. Clin Neuropharmacol 1988; 11: 45-55
-
(1988)
Clin Neuropharmacol
, vol.11
, pp. 45-55
-
-
Golbe, L.I.1
Lieberman, A.N.2
Muenter, M.D.3
-
33
-
-
0024448301
-
Long-term efficacy and safety of deprenyl (selegiline) in advanced Parkinson's disease
-
Golbe LI. Long-term efficacy and safety of deprenyl (selegiline) in advanced Parkinson's disease. Neurology 1989; 39: 1109-11
-
(1989)
Neurology
, vol.39
, pp. 1109-1111
-
-
Golbe, L.I.1
-
34
-
-
0025189747
-
L-deprenyl, levodopa pharmacokinetics, and response fluctuations in Parkinson's disease
-
Cedarbaum JM, Silvestri M, Clark M, et al. L-deprenyl, levodopa pharmacokinetics, and response fluctuations in Parkinson's disease. Clin Neuropharmacol 1990; 13: 29-35
-
(1990)
Clin Neuropharmacol
, vol.13
, pp. 29-35
-
-
Cedarbaum, J.M.1
Silvestri, M.2
Clark, M.3
-
35
-
-
0027484272
-
Selegiline in de novo parkinsonian patients: The Finnish study
-
Myllylä VV, Sotaniemi KA, Vuorinen JA, et al. Selegiline in de novo parkinsonian patients: the Finnish study. Mov Disord 1993; 1; S41-4
-
(1993)
Mov Disord
, vol.1
-
-
Myllylä, V.V.1
Sotaniemi, K.A.2
Vuorinen, J.A.3
-
36
-
-
0024343466
-
The effect of deprenyl (selegiline) on the natural history of Parkinson's disease
-
Tetrud JW, Langston JW. The effect of deprenyl (selegiline) on the natural history of Parkinson's disease. Science 1989; 45: 519-22
-
(1989)
Science
, vol.45
, pp. 519-522
-
-
Tetrud, J.W.1
Langston, J.W.2
-
37
-
-
0027524961
-
Symptomatic effect of selegiline in de novo parkinsonian patients
-
Allain H, Pollak P, Neukirch HC, et al. Symptomatic effect of selegiline in de novo parkinsonian patients. Mov Disord 1993; 8: S36-40
-
(1993)
Mov Disord
, vol.8
-
-
Allain, H.1
Pollak, P.2
Neukirch, H.C.3
-
38
-
-
0025358344
-
Selegiline in Parkinson's disease
-
Teräväinen H. Selegiline in Parkinson's disease. Acta Neurol Scand 1990; 81: 333-6
-
(1990)
Acta Neurol Scand
, vol.81
, pp. 333-336
-
-
Teräväinen, H.1
-
39
-
-
0028897256
-
Comparative study of selegiline plus L-dopa-carbidopa versus L-dopa-carbidopa alone in the treatment of Parkinson's disease
-
Brannan T, Yahr M. Comparative study of selegiline plus L-dopa-carbidopa versus L-dopa-carbidopa alone in the treatment of Parkinson's disease. Ann Neurol 1995; 37: 95-8
-
(1995)
Ann Neurol
, vol.37
, pp. 95-98
-
-
Brannan, T.1
Yahr, M.2
-
40
-
-
0024805879
-
Combination of a dopamine agonist, MAO-B inhibiitor and levodopa: A new strategy in the treatment of early Parkinson's disease
-
Rinne UK. Combination of a dopamine agonist, MAO-B inhibiitor and levodopa: a new strategy in the treatment of early Parkinson's disease. Acta Neurol Scand 1989; 126: 165-9
-
(1989)
Acta Neurol Scand
, vol.126
, pp. 165-169
-
-
Rinne, U.K.1
-
41
-
-
0026623522
-
Deprenyl effects on levodopa pharmacodynamics, mood, and free radical scavenging
-
Baronti F, Davis TL, Boldry RC, et al. Deprenyl effects on levodopa pharmacodynamics, mood, and free radical scavenging. Neurology 1992; 42: 541-4
-
(1992)
Neurology
, vol.42
, pp. 541-544
-
-
Baronti, F.1
Davis, T.L.2
Boldry, R.C.3
-
42
-
-
0024850759
-
Selegiline as an adjunct to conventional levodopa therapy in Parkinson's disease: Experience with this type B monoamine oxidase inhibitor in 200 patients
-
Elizan TS, Yahr MD, Moros DA, et al. Selegiline as an adjunct to conventional levodopa therapy in Parkinson's disease: experience with this type B monoamine oxidase inhibitor in 200 patients. Arch Neurol 1989; 48: 1280-3
-
(1989)
Arch Neurol
, vol.48
, pp. 1280-1283
-
-
Elizan, T.S.1
Yahr, M.D.2
Moros, D.A.3
|