Weekly paclitaxel and cisplatin with concurrent radiotherapy in locally advanced non-small-cell lung cancer: A phase I study

Journal of Clinical Oncology

Volumn 15, Issue 4, 1997, Pages 1409-1417

  Frasci, G ^a   Comella, P ^a   Scoppa, G ^a   Guida, C ^a   Gravina, A ^a   Fiore, F ^a   Casaretti, R ^a   Daponte, A ^a   Parziale, A ^a   Comella, G ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; CREMOPHOR; DEXAMETHASONE; PACLITAXEL; PROMETHAZINE; RANITIDINE; SEROTONIN 3 ANTAGONIST;

ADULT; AGED; ANEMIA; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; ESOPHAGITIS; FEMALE; HUMAN; HUMAN TISSUE; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LUNG NON SMALL CELL CANCER; LUNG TOXICITY; MALE; NEUROTOXICITY; NEUTROPENIA; PHASE 1 CLINICAL TRIAL; PRACTICE GUIDELINE; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; THROMBOCYTOPENIA;

EID: 0030958096     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1997.15.4.1409     Document Type: Article

References (37)

1. Boring CC, Squires TS, Tong T: Cancer statistics, 1994. Ca 44:7-26, 1994
2. Thompson DT: Conservative resection in surgery for bronchogenic carcinoma. J Thorac Cardiovasc Surg 53:159-162, 1967
3. Mountain C: A new international classification system for lung cancer. Chest 89:2255-2335, 1986 (suppl)
4. Perez CA, Pajak TF, Rubin P, et al: Long term observations of the patterns of failure in patients with unresectable non-oat cell carcinoma of the lung treated with definitive radiotherapy. Cancer 59:1847-1881, 1987
5. Dillman RO, Seagren SL, Propert KJ, et al: A randomized trial of induction chemotherapy plus high-dose radiation versus radiation alone in stage III non-small cell lung cancer. N Engl J Med 323:940-945, 1990
6. Le Chevalier T, Arriagada R, Quoix E, et al: Radiotherapy alone versus combined chemotherapy and radiotherapy in non-resectable non-small cell lung cancer: First analysis of a randomized trial in 353 patients. J Natl Cancer Inst 83:417-423, 1991
7. Schaake-Koning C, Van Den Boggaert W, Delasio O, et al: Effects of concomitant cisplatin and radiotherapy on inoperable non-small cell lung cancer. N Engl J Med 326:524-530, 1992
8. Non-Small Cell Lung Cancer Collaborative Group: Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trial. Br Med J 311:899-909, 1995
9. Sause WT, Scott C, Taylor S, et al: Radiation Therapy Oncology Group (RTOG) 88-08 and Eastern Cooperative Oncology Group (ECOG) 4588: Preliminary results of a phase III trial in regionally advanced unresectable non-small cell lung cancer. J Natl Cancer Inst 87:198-205, 1995
10. Dewitt L: Combined treatment of radiation and cisdiamminedichloroplatinum (II): A review of experimental and clinical data. Int J Radiat Oncol Biol Phys 13:403-426, 1987
11. Chang AY, Kim K, Glick J, et al: Phase II study of Taxol, merbarone, and piroxantrone in stage IV non-small cell lung cancer: The Eastern Cooperative Oncology Group results. J Natl Cancer Inst 85:388-394, 1993
12. Murphy WK, Fossella FV, Winn RJ, et al: Phase II study of Taxol in patients with untreated advanced non-small cell lung cancer. J Natl Cancer Inst 85:384-388, 1993
13. Klastersky J, and Sculier JP: Dose-finding study of paclitaxel (Taxol) plus cisplatin in patients with non-small cell lung cancer. Semin Oncol 21:39-43, 1994 (suppl 8)
14. Langer CJ, Leighton JC, Comis RL, et al: Paclitaxel and carboplatin in combination in the treatment of advanced non-small cell lung cancer: A phase II toxicity, response, and survival analysis. J Clin Oncol 13:1860-1870, 1995
15. Bonomi P, Kim K, Chang A, et al: Phase III trial comparing etoposide cisplatin versus Taxol with cisplatin-G-CSF versus Taxol-cisplatin in advanced non-small cell lung cancer. An Eastern Cooperative Oncology Group (ECOG) trial. Proc Am Soc Clin Oncol 15:382, 1996 (abstr 1145)
16. Tishler RB, Geard RB, Hall EJ, et al: Taxol sensitizes human astrocytoma cells to radiation. Cancer Res 52:3495-3497, 1992
17. Steren A, Seven BU, Perras J, et al: Taxol sensitizes human ovarian cancer cells to radiation. Gynecol Oncol 48:252-258, 1993
18. Havemann K, Wolf M, Goerg C, et al: Paclitaxel and simultaneous radiation in the treatment of stage IIIa/b non-small cell lung cancer. Semin Oncol 22:19-22, 1995 (suppl 14)
19. Choy H, Akerley W, Safran H, et al: Phase I trial of outpatient weekly paclitaxel and concurrent radiation therapy for advanced non-small cell lung cancer. J Clin Oncol 12:2682-2686, 1994
20. Belani CP, Aisner I, Hiponia D, et al: Paclitaxel and carboplatin with concurrent thoracic radiotherapy for regionally advanced non-small cell lung cancer. Proc Am Soc Clin Oncol 15:396, 1996 (abstr 1201)
21. Miller AB, Hoogstraten B, Staquet M, et al: Reporting results of cancer treatment. Cancer 47:207-214, 1981
22. Kaplan ES, Meier P: Non parametric estimation for incomplete observations. J Am Stat Assoc 53:557-580, 1958
23. Jeremic B, Shibamoto Y, Acimovic L, et al: Hyperfractionated radiation therapy with or without concurrent low-dose daily carboplatin/etoposide for stage III non-small cell lung cancer: A randomized study. J Clin Oncol 14:1065-1070, 1996
24. Strauss GM, Herndon JE, Sherman DD, et al: Induction chemoradiation followed by surgery in stage IIIA non-small cell lung carcinoma of the lung (NSCLC): Long term results of Cancer Leukemia Group B protocol 8634. Proc Am Soc Clin Oncol 15:376, 1996 (abstr 1121)
25. Lee JS, Scott C, Komaki R, et al: Concurrent chemoradiation therapy with oral etoposide and cisplatin for locally advanced inoperable non-small-cell lung cancer: Radiation Therapy Oncology Group protocol 91-06. J Clin Oncol 14:1055-1064, 1996
26. Greco A, Stroup SL, Gray JR, et al: Paclitaxel in combination chemotherapy with radiotherapy in patients with unresectable stage III non-small-cell lung cancer. J Clin Oncol 14:1642-1648, 1996
27. Choy H, Akerley W, Safran H, et al: Phase II trial of weekly paclitaxel and concurrent radiation therapy for locally advanced non-small cell lung cancer. Proc Am Soc Clin Oncol 15:371, 1996 (abstr 1098)
28. Akerley W, Choy H, Glantz M, et al: Weekly paclitaxel for metastatic non-small cell lung cancer: A phase I trial. Proc Am Soc Clin Oncol 15:377, 1996 (abstr 1122).
29. Frasci G, Comella P, Parziale A, et al: Cisplatin/paclitaxel weekly administration in advanced solid neoplasms. A phase I, dose finding study. Proc Am Soc Clin Oncol 15:480, 1996 (abstr 1523)
30. Niell HB, Miller AA, Kumar P, et al: Phase I/II trial of paclitaxel, cisplatin and radiation therapy for stage III non-small cell lung cancer. Proc Am Soc Clin Oncol 15:389, 1996 (abstr 1173)
31. Langer C, Rosvold L, Kaplan R, et al: Induction chemotherapy with paclitaxel and carboplatin followed by concurrent chemoradiotherapy in unresectable, locally advanced non-small cell lung carcinoma: Preliminary report of FCCC 94-001. Proc Am Soc Clin Oncol 15:376, 1996 (abstr 1118)
32. Antonia SJ, Wagner H, Williams C, et al: Concurrent paclitaxel/cisplatin with thoracic radiation in patients with stage IIIA/B non-small-cell carcinoma of the lung. Semin Oncol 22:34-37, 1995 (suppl 9)
33. Aisner J, Belani CP, Kearns C, et al: Feasibility and pharmacokinetics of paclitaxel, carboplatin and concurrent radiotherapy for regionally advanced squamous cell carcinoma of the head and neck and for regionally advanced non-small cell lung cancer. Semin Oncol 22:17-21, 1995 (suppl 12)
34. Hazuka MB, Turrisi AT III, Martel MK, et al: Dose-escalation in non-small cell lung cancer (NSCLC) using conformal 3-dimensional radiation treatment planning (3DRTP): Preliminary results of a phase I study. Proc Am Soc Clin Oncol 13:336, 1994 (abstr 1119)
35. Schuchter L, Glick J: The current status of WR-2721 (amifostine): A chemotherapy and radiation therapy protector. Biol Ther Cancer Update 1:1-10, 1993
36. List AF, Heaton R, Glinsmann-Gibson B, et al: Amifostine protects primitive human hematopoietic progenitors against cytotoxicity from diverse antineoplastics. Proc Am Soc Clin Oncol 15:532, 1996 (abstr 1723)
37. DiPaola R, Rodriguez R, Recio A, et al: A phase I study of amifostine and paclitaxel in patients with advanced malignancies. Proc Am Soc Clin Oncol 15:488, 1996 (abstr 1556)