Effect of cations on the tyrosine kinase activity of the insulin receptor: Inhibition by fluoride is magnesium dependent

Molecular and Cellular Biochemistry

Volumn 171, Issue 1-2, 1997, Pages 69-73

  Viñals, Francesc ^a   Camps, Marta ^a   Testar, Xavier ^a   Palacín, Manuel ^a   Zorzano, Antonio ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Fluoride; Insulin receptors; Skeletal muscle; Tyrosine kinase activity

Indexed keywords

ADENOSINE TRIPHOSPHATE; CATION; DIVALENT CATION; FLUORIDE; INSULIN RECEPTOR; MAGNESIUM ION; MANGANESE; MUSCLE ENZYME; MUSCLE PROTEIN; PHOSPHOTRANSFERASE; PROTEIN TYROSINE KINASE;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; NONHUMAN; PROTEIN PURIFICATION; RAT; SKELETAL MUSCLE;

ANIMALS; CATIONS, DIVALENT; FLUORIDES; MAGNESIUM; MALE; MANGANESE; MUSCLE, SKELETAL; PROTEIN-TYROSINE KINASES; RATS; RATS, WISTAR; RECEPTOR, INSULIN;

EID: 0030957850     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006836001489     Document Type: Article

References (27)

1. Ebina Y, Ellis L, Jarnagin K, Edery M, Graf L, Clauser E, Ou J, Masiarz F, Kan YW, Goldfine ID, Roth RA, Rutter WJ: The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling. Cell 40: 747-758, 1985
2. Ullrich A, Bell JR, Chen EY, Herrera R, Petruzzelli LM, Dull TJ, Gray A, Coussens L, Liao YC, Tsubokawa M, Mason A, Seeburg PH, Grunfeld C, Rosen OM, Ramachandran J: Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature 313: 756-761, 1985
3. Rosen OM: After insulin binds. Science 237: 1452-1458, 1989
4. Kasuga M, Karlsson FA, Kahn CR: Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor. Science 215: 185-187, 1982
5. Kasuga M, Zick Y, Blithe DL, Karlsson FA, Haring HU, Kahn CR: Insulin stimulation of phosphorylation of the β subunit of the insulin receptor. J Biol Chem 257: 9891-9894, 1982
6. Petruzzelli L, Herrera R, Rosen OM: Insulin receptor is an insulin-dependent tyrosine protein kinase: Copurification of insulin-binding activity and protein kinase activity to homogeneity from human placenta. Proc Natl Acad Sci USA 81: 3327-3331, 1984
7. Herrera R, Rosen OM: Autophorphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activation. J Biol Chem 261: 11980-11985, 1986
8. Perlman R, Bottaro DP, White MF, Kahn CR: Conformational changes in the α- and β-subunits of the insulin receptor identified by antipeptide antibodies. J Biol Chem 264: 8946-8950, 1989
9. Baron V, Kaliman P, Gautier N, Van Obberghen E: The insulin receptor activation process involves localized conformational changes. J Biol Chem 267: 23290-23294, 1992
10. Rosen OM, Herrera R, Olowe Y, Petruzzelli LM, Cobb M: Phosphorylation activates the insulin receptor tyrosine protein kinase. Proc Natl Acad Sci USA 80: 3237-3240, 1983
11. Yu KT, Czech MP: Tyrosine phosphorylation of the insulin receptor β subunit activates the receptor-associated tyrosine kinase activity. J Biol Chem 259: 5277-5286, 1984
12. White MF, Takayama S, Kahn CR: Differences in the sites of phosphorylation of the insulin receptor in vivo and in vitro. J Biol Chem 260: 9470-9478, 1985
13. White MF, Kahn CR: The insulin signalling system. J Biol Chem 269: 1-4, 1994
14. Viñals F, Testar X, Palacín M, Zorzano A: Inhibitory effect of fluoride on insulin receptor autophosphorylation and tyrosine kinase activity. Biochem J 291: 615-622, 1993
15. Camps M, Gumà A, Testar X, Palacím M, Zorzano A: Insulin resistance of skeletal muscle during pregnancy is not a consequence of intrinsic modifications of insulin receptor binding or kinase activities. Endocrinology 127: 2561-2570, 1990
16. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976
17. Avruch J, Nemenoff RA, Blackshear PJ, Pierce MW, Osathanondh R: Insulin-stimulated tyrosine phosphorylation of the insulin receptor in detergent extracts of human placental membranes. J Biol Chem 257: 15162-15166, 1982
18. White MF, Haring HU, Kasuga M, Kahn CR: Kinetic properties and sites of autophosphorylation of the partially purified insulin receptor from hepatoma cells. J Biol Chem 259: 255-264, 1984
19. Kwok YC, Nemenoff RA, Powers AC, Avruch J: Kinetic properties of the insulin receptor tyrosine protein kinase: Activation through an insulin-stimulated tyrosine-specific, intramolecular autophosphorylation. Arch Biochem Biophys 244: 102-113, 1986
20. Sasaki N, Rees-Jones RW, Zick Y, Nissley SP, Rechler MM: Characterization of insulin-like growth factor I-stimulated tyrosine kinase activity associated with the b-subunit of type I insulin-like growth factor receptors of rat liver cells. J Biol Chem 260: 9793-9804, 1985
21. Nemenoff RA, Kwok YC, Shulman GI, Blackshear PJ, Osathanondh R, Avruch J: Insulin-stimulated tyrosine protein kinase. Characterization and relation to the insulin receptor. J Biol Chem 259: 5058-5065, 1985
22. Pike LJ, Kuenzel EA, Casnellie JE, Krebs EG: A comparison of the insulin- and epidermal growth factor-stimulated protein kinases from human placenta. J Biol Chem 259: 9913-9921, 1984
23. Srivastava AK, Chiasson JL: Comparative characterization of receptor and non-receptor associated protein tyrosine kinases. Biochim Biophys Acta 996: 13-18, 1989
24. Smith RM, Martell AE: Critical Stability Constants. Plenum Press, New York, 1976
25. Antonny B, Bigay J, Chabre M: A novel magnesium-dependent mechanism for the activation of transducin by fluoride. FEES Lett 268: 277-280, 1990
26. Antonny B, Sukumar M, Bigay J, Chabre M, Higashijima T: The mechanism of aluminum-dependent G-protein activation by fluoride and magnesium. J Biol Chem 268: 2393-2402, 1993
27. Murphy AJ, Coll RJ: Fluoride is a slow, tight-binding inhibitor of the calcium ATPase of sarcoplasmic reticulum. J Biol Chem 267: 5229-5235, 1992