Stereospecific internal almylation of terminal γ,δ-epoxy acrylates

Tetrahedron Letters

Volumn 38, Issue 19, 1997, Pages 3419-3422

  Miyazawa, Masahiro ^a   Ishibashi, Naoki ^a   Ohnuma, Satoshi ^a   Miyashita, Masaaki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLIC ACID DERIVATIVE; EPOXIDE;

ALKYLATION; ARTICLE; CHIRALITY; DRUG SYNTHESIS; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030957830     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00635-7     Document Type: Article

References (17)

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10. 2b
11. Schmid, C. R.; Bryant, J. D.; Org. Synth., 1995, 72, 6.
12. +): 142.0630. Found: 142.0621.
13. ++1, 0.8%), 128 (100), 113 (43), 100 (90), 82 (65), 55 (64).
14. 3)) was prepared from methyl (S)-(+)-3-hydroxy-2-methylpropionate.
15. Trost, B. M.; Belletire, J. L.; Godleski, S.; McDougal, P. G.; Balkovec, J. M.; Baldwin, J. J.; Christy, M. E., Ponticello, G. S.; Varga, S. L.; Springer, J. P.; J. Org. Chem., 1986, 51, 2370.
16. The value is presumably due to the purity of the substrate.
17. 3).