Short-term effects of growth hormone and insulin-like growth factor I on cancellous bone in rhesus macaque monkeys

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 4, 1997, Pages 1202-1209

  Sass, D A ^a   Jerome, C P ^b   Bowman, A R ^a   Bennett Cain, A ^b   Ginn, T A ^b   LeRoith, D ^c   Epstein, S ^a  

^a ALBERT EINSTEIN MEDICAL CENTER   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCEIN; GROWTH HORMONE; OSTEOCALCIN; RECOMBINANT GROWTH HORMONE; RECOMBINANT SOMATOMEDIN C; RNA; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MASS; BONE MINERALIZATION; BONE REMODELING; CANCELLOUS BONE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; FEMUR; GENE EXPRESSION; HORMONE ACTION; INTRAVENOUS DRUG ADMINISTRATION; LUMBAR VERTEBRA; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOCLAST; PRIORITY JOURNAL; RHESUS MONKEY; SUBCUTANEOUS DRUG ADMINISTRATION; TIBIA;

ANIMALS; BONE AND BONES; FEMALE; GENE EXPRESSION; GROWTH HORMONE; HUMAN GROWTH HORMONE; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; MACACA MULATTA; OSTEOCALCIN; OSTEOGENESIS; RECOMBINANT PROTEINS; RNA, MESSENGER; TIME FACTORS;

EID: 0030957618     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.4.1202     Document Type: Article

References (39)

1. Canalis E. 1995 Growth hormone, skeletal growth factors and osteoporosis. Endocr Pract. 1:39-43.
2. Canalis E. 1993 Systemic and local factors and the maintenance of bone quality. Calcif Tissue Int 53(Supp1):S90-S93.
3. Slootweg MC, van Buul-Offers SC, Herrmann-Erlee PM, van der Meer JM, Duursma SA. 1988 Growth hormone is mitogenic of fetal mouse osteoblasts but not for undifferentiated bone cells. J Endocrinol. 116:R11-R13.
4. Bouillon R. 1991 Growth hormone and bone. Horm Res. 36(Suppl):49-55.
5. Brixen K, Nielsen HK, Mosekilde L, Flyvbjerg A. 1990 A short course of recombinant human growth hormone treatment stimulates osteoblasts and activates bone remodeling in normal human volunteers. J Bone Miner Res. 6:609-618.
6. Schlechter NL, Russell SM, Spencer M, Nicoll CS. 1986 Evidence suggesting that the direct growth-promoting effect of growth hormone on cartilage in vivo is mediated by local production of somatomedin. Proc Natl Acad Sci USA. 6:7932-7934.
7. Isaksson OGP, Lindahl A, Nilsson A, Isgaard J. 1987 Mechanism of the stimulatory effect of growth hormone on longitudinal bone growth. Endocr Rev. 8:426-438.
8. Ernst M, Rodan GA. 1990 Increased activity of IGF in osteoblastic cells in the presence of GH: positive correlation with the presence of the GH-induced IGF-BP3. Endocrinology. 127:807-814.
9. McCarthy TL, Centrella M, Canalis E. 1989 Regulatory effects of insulin-like growth factors 1 and 11 on bone collagen synthesis in rat calvarial cultures. Endocrinology. 124:301-309.
10. Hock JM, Centrella M, Canalis E. 1988 Insulin-like growth factor-1 (IGF-I) has independent effects on bone matrix formation and cell replication. Endocrinology. 122:254-260.
11. Mochizuki H, Hakeda Y, Wakatsuki N, et al. 1992 Insulin-like growth factor-I supports formation and activation of osteoclasts. Endocrinology. 131:1075-1080.
12. Tobias JH, Chow JWM, Chambers TJ. 1992 Opposite effects of insulin-like growth factor-1 on the formation of trabecular and cortical bone in adult female rats. Endocrinology. 131:2387-2392.
13. Ibbotson KJ, Orcutt CM, D'Souza SM, et al. 1992 Contrasting effects of parathyroid hormone and insulin-like growth factor 1 in an aged ovariectomized rat model of postmenopausal osteoporosis. J Bone Miner Res. 7:425-432.
14. Spencer EM, Liu CC, Si ECC, Howard GA. 1991 In vitro actions of insulin-like growth factor-1 (IGF-I) on bone formation and resorption in rats. Bone. 12:21-26.
15. Kalu DN, Liu CC, Salerno E, et al. 1991 Insulin-like growth factor-1 partially prevents ovariectomy-induced bone loss: a comparative study with human parathyroid hormone (1-38). J Bone Miner Res 6:S221.
16. Mueller K, Cortesi R. 1991 Insulin-like growth factor-1 increases trabecular bone mass on the ovariectomised rat. J Bone Miner Res 6:S221.
17. Ghiron LJ, Thompson JL, Holloway L, et al. 1995 Effects of recombinant insulin-like growth factor-1 and growth hormone on bone turnover in elderly women. J Bone Miner Res. 10:1844-1852.
18. Ebeling PR, Jones JD, O'Fallon WM, Janes CH, Riggs BL. 1993 Short-term effects of recombinant human insulin-like growth factor I on bone turnover in normal women. J Clin Endocrinol Metab. 77:1384-1387.
19. Kupfer SR, Underwood LE, Baxter RC, Clemmons DR. 1993 Enhancement of the anabolic effects of GH and IGF-I by use of both agents simultaneously. J Clin Invest. 91:391-396.
20. Mann DR, Gould KG, Collins DC. 1990 A potential model for bone loss resulting from medical oophorectomy or menopause. J Clin Endocrinol Metab. 71:105-110.
21. Longcope C, Hoberg L, Steuterman S, Baran D. 1989 The effect of ovariectomy on spine bone mineral density in rhesus monkeys. Bone. 10:341-344.
22. Pope NS, Gould KG, Anderson DC, Mann DR. 1989 Effects of age and sex on bone density in the rhesus macaque. Bone. 10:109-112.
23. Aguilo F, Cabrera R. 1989 Validation of single photon absorptiometry in estimating bone mineral mass in rhesus monkey skeletons. PR Health Sci J. 8:205-209.
24. Goodman AL, Descalzi CD, Johnson DK, Hodgen GD. 1977 Composite pattern of circulating LH, FSH, estradiol and progesterone during the menstrual cycle of cynomolgus monkeys. Proc Soc Exp Biol Med. 155:478-481.
25. Van Wagenen G. 1970 Menopause in a subhuman primate. Anat Rec. 166:329.
26. Albini CH, Sotos J, Sherman B, et al. 1991 Diagnostic significance of urinary growth hormone measurements in children and growth failure: correlation between serum and urine growth hormone. Pediatr Res. 29:619-622.
27. Lieberman SA, Bukar J, Chen SA, et al. 1992 Effects of recombinant human insulin-like growth factor-1 on total and free IGF-I concentrations, IGF-binding proteins, and glycemic response in humans. J Clin Endocrinol Metab. 75:30-36.
28. Baron R, Vignery A, Neff L, Silverglate A, Santa Maria A. 1983 Processing of undecalcified bone specimens for bone histomorphometry. In: Recker RR, ed. Bone histomorphometry: techniques and interpretation. Boca Raton: CRC Press; 13-35.
29. Parfitt AM. 1983 The stereologic basis of bone histomorphometry. Theory of quantitative microscopy and reconstruction of the third dimension. In: Recker RR, ed. Bone histomorphometry. Techniques and interpretations. Boca Raton: CRC Press; 53-87.
30. Parfitt AM, Drezner MK, Glorieux FH, et al. 1987 Bone histomorphometry: standardization of nomenclature, symbols and units. Report of the ASBMR Histomorphometry Committee. J Bone Miner Res. 2:595-610.
31. Nemeth GG, Heydemann A, Bolander ME. 1989 Isolation and analysis of ribonucleic acids from skeletal tissue. Anal Biochem. 183:301-304.
32. Lian J, Stewart C, Puchacz E. 1989 Structure of the rat osteocalcin gene and regulation of vitamin D-dependent expression. Proc Natl Acad Sci USA. 86:1143.
33. Tokunaga K, Taniguchi H, Yoda K, Shimizu M, Sakiyama S. 1986 Nucleotide sequence of a full-length cDNA for mouse cytoskeletal B actin mRNA. Nucleic Acids Res. 14:2829.
34. Winer BJ. 1971 Statistical principles in experimental design, 2nd ed. New York: McGraw-Hill.
35. LeRoith D, Yanowski J, Kaldijan EP, et al. 1996 The effects of growth hormone and IGF-I on the immune system of aged female monkeys. Endocrinology. 137:1071-1079.
36. Wilson ME. 1995 IGF-I administration advances the decrease in hypersensitivity to oestradiol negative feedback inhibition of serum LH in adolescent female rhesus monkeys. J Endocrinol. 145:121-130.
37. D'Ercole AJ, Stiles AD, Underwood LE. 1984 Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci USA. 82:935-939.
38. Corpas E, Harman SM, Blackman MR. 1993 Human growth hormone and human aging. Endocr Rev. 14:20-39.
39. Low LCK, Wang PT, Cheung PT, et al. 1988 Long term pulsatile growth hormone (GH)-releasing hormone therapy in children with growth hormone deficiency. J Clin Endocrinol Metab. 66:611-617.