S-Methylcysteine and cysteine are inhibitors of induction of glutathione S-transferase placental form-positive foci during initiation and promotion phases of rat hepatocarcinogenesis

Japanese Journal of Cancer Research

Volumn 88, Issue 5, 1997, Pages 435-442

  Takada, Nobuyasu ^a   Yano, Yoshihisa ^a   Wanibuchi, Hideki ^a   Otani, Shuzo ^a   Fukushima, Shoji ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cysteine; Polyamine biosynthesis; Rat hepatocarcinogenesis; S Methylcysteine

Indexed keywords

CYCLINE; CYSTEINE; DIETHYLNITROSAMINE; GLUTATHIONE TRANSFERASE; MESSENGER RNA; ORGANOSULFUR DERIVATIVE; PLANT EXTRACT; S METHYLCYSTEINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; BODY WEIGHT; CANCER PREVENTION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DOWN REGULATION; EARLY RESPONSE GENE; ENZYME INDUCTION; ENZYME INHIBITION; LIVER CANCER; LIVER CARCINOGENESIS; LIVER CELL; LIVER WEIGHT; MALE; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; ONCOGENE C MYC; ORAL DRUG ADMINISTRATION; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTO ONCOGENE; RAT;

EID: 0030957291     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1997.tb00401.x     Document Type: Article

References (27)

1. Takada, N., Matsuda, T., Otoshi, T., Yano, Y., Otani, S., Hasegawa, T., Nakae, D., Konishi, Y. and Fukushima, S. Enhancement by organosulfur compounds from garlic and onions of diethylnitrosamine-induced glutathione S-transferase positive foci in the rat liver. Cancer Res., 54, 2895-2899 (1994).
2. Takada, N., Kitano, M., Chen, T., Yano, Y., Otani, S., and Fukushima, S. Enhancing effects of organosulfur compounds from garlic and onions on hepatocarcinogenesis in rats: association with increased cell proliferation and elevated ornithine decarboxylase activity. Jpn. J. Cancer Res., 85, 1067-1072 (1994).
3. Matsuda, T., Takada, N., Yano, Y., Wanibuchi, H., Otani, S. and Fukushima, S. Dose-dependent inhibition of glutathione S-transferase placental form-positive hepatocellular foci induction of the rat by methyl propyl disulfide and propylene sulfide from garlic and onions. Cancer Lett., 86, 229-234 (1994).
4. Suzuki, T., Sugii, M. and Kakimoto, T. New γ-glutamyl peptides in garlic. Chem. Pharm. Bull., 9, 77-78 (1961).
5. Thompson, J. F., Morris, C. J. and Zacharius, R. M. Isolation of (-) S-methyl-L-cysteine from beans (Phaseolus vulgaris). Nature, 178, 593 (1956).
6. Synge, R. L. M. and Wood, J. C. (+)-(S-Methyl-L-cysteine S-oxide) in cabbage. Biochem. J., 64, 252-259 (1956).
7. Sumiyoshi, H. and Wargovich, M. J. Chemoprevention of 1,2-dimethylhydrazine-induced colon cancer in mice by naturally occurring organosulfur compounds. Cancer Res., 50, 5084-5087 (1990).
8. Ito, N., Tsuda, H., Tatematsu, M., Inoue, T., Tagawa, Y., Aoki, T., Uwagawa, S., Kagawa, M., Ogiso, T., Masui, T., Imaida, K., Fukushima, S. and Asamoto, M. Enhancing effects of various hepatocarcinogenes on induction of preneoplastic glutathione S-transferase placental form positive foci in rat - an approach for a new medium-term bioassay system. Carcinogenesis, 9, 387-394 (1988).
9. Tsuda, H., Uehara, N., Iwahori, Y., Asamoto, M., Iigo, M., Nagao, M., Matsumoto, K., Ito, M. and Hirono, I. Chemopreventive effects of β-carotene, α-tocopherol and five naturally occurring antioxidants on initiation of hepatocarcinogenesis by 2-amino-3-methylimidazo[4,5-f]quinoline in the rat. Jpn. J. Cancer Res., 85, 1214-1219 (1994),
10. O'Brien, T. G., Simsiman, R. C. and Boutwell, R. K. Induction of polyamine-biosynthetic enzymes in mouse epidermis and their specificity for tumor promotion. Cancer Res., 35, 2426-2433 (1975).
11. Babaya, K., Izumi, K., Ozono, S., Miyata, Y., Morikawa, A., Chmiel, J. S. and Oyasu, R. Capability of urinary components to enhance ornithine decarboxylase activity and promote urothelial tumorigenicity. Cancer Res., 43, 1774-1782 (1983).
12. 1-acetyltransferase, a new biochemical marker for epithelial proliferation in rat bladder. Jpn. J. Cancer Res., 83, 1037-1040 (1992).
13. Chirgwin, J. W., Przybyla, A. E., MacDonald, R. J. and Rutter, W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18, 5294-5299 (1979).
14. Hsu, S. M., Raine, L. and Fanger, H. Use of avidin-biotinperoxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem., 29, 577-580 (1981).
15. Satoh, K., Kitahara, A., Soma, Y., Inaba, Y., Hatama, I. and Sato, K. Purification, induction and distribution of placental glutathione transferase: a new marker enzyme for preneoplastic cells in rat chemical carcinogenesis. Proc. Natl. Acad. Sci. USA, 82, 3964-3968 (1985).
16. Otani, S., Matsui, I., Nakajima, S., Masutani, M., Mizoguchi, Y. and Morisawa, S. Induction of ornithine decarboxylase in guinea-pig lymphocytes by the divalent cation ionophore A23187 and phytohemagglutinin. J. Biochem., 88, 77-85 (1980).
17. Matsui, I., Wiegand, L. and Pegg, A. E. Properties of spermine N-acetyltransferase from livers of rats treated with carbon tetrachloride and its role in conversion of spermine into putrescine. J. Biol. Chem., 256, 2454-2459 (1981).
18. Sparnins, V. L., Brany, G. and Wattenberg, L. W. Effects of organosulfur compounds from garlic and onions on benzopyrene-induced neoplasia and glutathione S-transferase activity in the mouse. Carcinogenesis, 9, 131-134 (1988).
19. Wargovich, M. J. Diallyl sulfide, a flavor component of garlic (Allium sativum), inhibits dimethylhydrazine-induced colon cancer. Carcinogenesis, 8, 487-489 (1987).
20. Wargovich, M. J., Woods, C., Eng, V. W. S., Stephens, L. C. and Grey, K. Chemoprevention of N-nitrosomethyl-benzylamine-induced esophageal cancer in rats by the naturally occurring thioether, diallyl sulfide. Cancer Res., 48, 6872-6875 (1988).
21. Ames, B. N. and Golds, L. S. Mitogenesis increases mutagenesis. Science, 249, 970-977 (1990).
22. Cohen, S. M. and Ellwein, L. B. Cell proliferation in carcinogenesis. Science, 249, 1007-1011 (1990).
23. Holladay, K., Fujiki, H. and Bowden, G. T. Okadaic acid induces expression of both early and secondary response genes in mouse keratinocytes. Mol. Carcinog., 5, 16-24 (1992).
24. Park, K., Chung, M. and Kim, S.-J. Inhibition of myogenesis by okadaic acid, an inhibitor of protein phosphates 1 and 2A, correlates with the induction of AP-1. J. Biol. Chem., 267, 10810-10815 (1992).
25. Ohta, T., Sueoka, E., Iida, N., Komori, A., Suganuma, M., Nishikawa, R., Tatematsu, M., Kim, S.-J., Carmichael, W. W. and Fujiki, H. Nodularin, a potent inhibitor of protein phosphatases 1 and 2A, is a new environmental carcinogen in male F344 rat liver. Cancer Res., 54, 6402-6406 (1994).
26. Nakabeppu, Y. and Nathans, D. The basic region of Fos mediates specific DNA binding. EMBO J., 8, 3833-3841 (1989).
27. Halazonetis, T. D., Georgopoulos, K., Greenberg, M. E. and Leder, P. c-jun dimerizes with itself and with c-fos, forming complexes of different DNA binding affinities. Cell, 55, 917-924 (1988).