Soluble T-lymphocyte antigen-specific immunoproteins: A progress report

Proceedings of the Society for Experimental Biology and Medicine

Volumn 214, Issue 3, 1997, Pages 204-209

  Cone, Robert E ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; IMMUNOGLOBULIN; T LYMPHOCYTE ANTIGEN;

ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; HUMAN; MOLECULAR GENETICS; PROTEIN ANALYSIS; REVIEW;

EID: 0030956445     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: 10.3181/00379727-214-44088     Document Type: Review

References (39)

1. Klinman NR, Linton P-J. The clonotype repertoire of B cell subpopulations. Adv Immunol 42:1-94, 1988.
2. Matis LA. Basis of T-cell specificity. Annu Rev Immunol 8:65-82, 1992.
3. Cone RE. Soluble T lymphocyte antigen-specific molecules. Proc Soc Exp Biol Med 200:296-302, 1992.
4. Cone RE. Soluble extracellular antigen-specific T cell immunoproteins. J Leukoc Biol 59:605, 1996.
5. Cone RE, Malley A. Soluble antigen-specific T cell immunoproteins. T lymphocyte-based humoral immunity? (viewpoint). Immunol Today 17:308, 1996.
6. Malley A, Zeleny-Pooley M, Murray G. Stabilization and characterization of antigen-specific T suppressor inducer and T suppressor effector molecules. J Immunol Methods 178:321-339, 1995.
7. Ferguson TA, Iverson GM. Isolation and characterization of an antigen-specific suppressor-inducer molecule from serum of hyperimmune mice using monoclonal antibody. J Immunol 137:3896-3902, 1986.
8. Cone RE, Beaman KD. Antigen binding molecules of T cells (TABM) charge heterogeneity and structural lability. Mol Immunol 22:399-406, 1985.
9. Cone RE, Weischedel AK, Kristie J, Urbanski M. Antigen binding by proteins secreted by an antigen-specific T cell hybrid. Mol Immunol 29:689-696, 1992.
10. Hubbard PA, Speidel M, Marchalonis JJ, Cone RE. A monoclonal antigen binding T-cell immunoprotein: Antigenic relatedness to T cell receptor β chain FrIV and J peptide segments. Physiochemical distinctiveness from classical immunoglobulins and T cell receptor heterodimers. Mol Immunol 26:447-455, 1989.
11. Cone RE, Marchalonis JJ. Partial amino acid sequence of monoclonal extracellular antigen-specific T cell proteins. Immunol Res 22:541, 1993.
12. Beaman KD, Ruddle NH, Bothwell ALM, Cone RE. Messenger RNA for an antigen-specific binding molecule from an antigen-specific T cell hybrid. Proc Nat Acad Sci U S A 81:1524-1528, 1984.
13. Bristow C, Marchalonis JJ. Solid-phase antigen binding by purified immunoproteins from antigen-specific monoclonal T cell hybridomas. Mol Immunol 26:611-624, 1989.
14. Chu B, Ferguson TA, Beaman KD, Rosenmann SJ, Cone RE, Flood P, Green DR. An approach to the unification of suppressor T cell circuits. A simplified assay for the induction of suppression by T cell-derived antigen-binding molecules (T-ABM). Cell Immunol 118:30-36, 1989.
15. Green DR, Chue B, Zheng H, Ferguson TA, Beaman TD, Flood P. A helper T cell clone produces an antigen-specific molecule (T-ABM) which functions in the induction of suppression. J Mol Cell Immunol 3:95-102, 1987.
16. Cone RE, Rosenstein RW, Janeway CA, Iverson GM, Murray JH, Cantor H, Fresno M, Mattingly JA, Cramer M, Krawinkel V, Wigzen H, Binz H, Frischnecht H, Ptak W, Gershon RK. Affinity-purified antigen-specific products produced by T cells share epitopes recognized by heterologous antisera raised against several different antigen-specific products from T cells. Cell Immunol 82:232-245, 1983.
17. Kuchroo VK, Byrne MC, Atsumi Y, Greenfield E, Connoly JB, Whitters MJ, Ohara R, Collins M, Dorf ME. T cell receptor α chain plays a critical role in antigen-specific suppressor cell function. Proc Nat Acad Sci U S A 88:8700, 1991.
18. Griffith TS, Herndon JS, Lima J, Kahn M, Ferguson TA. The immune response and the eye. TCR-α chain related molecules regulate the systemic immunity to antigen presented in the eye. Int Immunol 7:1617-1625, 1995.
19. Urbanski M, Cone RE. T cell-derived antigen specific immune response. J Immunol 148:2840-2847, 1994.
20. Urbanski M, Cone RE: T cell-derived antigen-specific immune response. II. Further characterization of the response and the antigen-binding T cell immunoproteins. Cell Immunol 153:131-141, 1994.
21. Paliwal V, Friedman AM, Ptak W, Askenase PW. Monoclonal, antigen-specific T cell contrasuppressor factor expresses determinants of TcR α-chain (not necessarily TcR β-chain), having a molecular mass of about 40 kDa. J Immunol 152:2811, 1994.
22. Perrin PJ, Philips M. The regulation of resistance to Shistosoma mansoni by a soluble α/β TCR analog, produced by a cloned T cell hybridoma. Cell Immunol 149:155-169, 1993.
23. Iwata M, Katarnwak M, Kubo R, Ishizaka K. Relationship between T cell receptors and antigen-binding factors. J Immunol 143:3909, 1989.
24. Bissonette R, Zheng H, Kubo RT, Singh B, Green DR. A helper T cell hybridoma produces an antigen-specific immunoregulatory activity. Relationship to the T cell receptor by serology and antigenic fine specificity. J Immunol 146:2898, 1991.
25. Kuchroo VK, Steele JK, Ohara R, Jayaraman S, Selvara P, Greenfield E, Kubo RT, Dorf ME. Relationships between antigen-specific helper and inducer T cell hybridomas. J Immunol 145: 438, 1990.
26. + suppressor T cells downregulate antibody responses also to unrelated antigens when the latter are presented as covalently-linked adducts with the specific antigen. Cell Immunol 150:168-193, 1993.
27. Fairchild RL, Palmer E, Moorhead JW. Production of DNP-specific/class I MHC-restricted suppressor molecules is linked to the expression of T cell receptor α and β chain genes. J Immunol 150:67, 1993.
28. Cone RE, Malley A. Serologic and primary amino acid sequence similarity between extracellular antigen-specific T cell proteins and TCR α chains. Ninth Intl Congr Immunol Abst 2411, 1995.
29. Nakano T, Ishii Y, Ishizaka K. Biochemical characterization of antigen-specific glycosylation inhibition factor from antigen-specific suppressor T cells. I. Identification of a 55 kilodalton glycosylation-inhibiting factor peptide with a TCR alpha-chain determinant. J Immunol 156:1728-1734, 1996.
30. Ishii Y, Nakano T, Ishizaka K. Biochemical characterization of antigen-specific glycosylation-inhibiting factor from antigen-specific suppressor T cells. II. The 55 kDa glycosylation-inhibiting factor peoptide is a derivative of TCR alpha-chain and a subunit of antigen-specific glycosylation-inhibiting factor. J Immunol 156:1735-1742, 1996.
31. Xavier RM, Nakamura M, Tsunematsu T. Isolation and characterization of a human non-specific suppressor factor from ascitic fluid of systemic lupus erythematosus. J Immunol 152:2624-2632, 1994.
32. Nakamura M, Xavier RM, Tsunematsu T, Tanigawa Y. Molecular cloning and characterization of a cDNA encoding monoclonal non-specific suppressor factor. Proc Nat Acad Sci U S A 92:3463-3467, 1995.
33. Onda P, Brunner T, Messier H, Bissonette R, Echevarri F, Baier G, Futedar A, Green DR: Immunoregulatory activity of a T cell receptor α chain demonstrated by in vitro transcription and translation. Proc Nat Acad Sci U S A 92:3004, 1995.
34. Shin J, Strominger JL. Translocation of TCR α chains into the lumen of the endoplasmic reticulum and their degradation. Science 259:1901, 1995.
35. Hadjikouti CA, Wang Y, O'Rourke J, Cone RE. Intracameral injection of antigen potentiates the production of antigen-specific T cell proteins in serum after the induction of delayed-type hypersensitivity. Invest Ophthalmol Vis Sci 36:1470, 1995.
36. Cone RE, Wang Y, O'Rourke J, Kosiewicz M, Okamoto S, Streilein JW. On the role of extracellular antigen-specific T cell proteins in immune deviation elicited by intracameral soluble protein antigens. In: Nussenblatt RB, Whitcup S, Caspi RR, Gery I, Eds. Advances in Ocular Immunology. Amsterdam: Elsevier, p169, 1994.
37. Wang Y, O'Rourke J, Cone RE. Serum TABM produced during anterior chamber-associated immune deviation passively transfers suppression of delayed-type hypersensitivity to primed mice. Intern Immunol (in press), 1997.
38. Wang Y, O'Rourke J, Cone RE. High dose cyclophosphamide inhibits anterior chamber-associated immune deviation (ACAID) and the production of extracellular antigen-specific T cell proteins induced by trinitrophenylated spleen cells. Cell Immunol 165: 284, 1995.
39. Dibrino M, Ravindran B, Cone RE. T cell-derived proteins from normal human sera and their relationship to T cell antigen-binding molecules. Clin Immunol Immunopathol 59:271-287, 1991.