Mepacrine decreases lung leak in rats given interleukin-1 intratracheally

American Journal of Respiratory and Critical Care Medicine

Volumn 155, Issue 5, 1997, Pages 1624-1628

  Lee, Young M ^a   Hybertson, Brooks M ^a   Terada, Lance S ^a   Repine, Alexander J ^a   Cho, Hyun G ^a   Repine, John E ^a  

^a Box C321 ^*

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; MEPACRINE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR;

ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CONTROLLED STUDY; ENZYME ACTIVITY; EXUDATE; HUMAN; HUMAN CELL; INFLAMMATION; LUNG EDEMA; LUNG INJURY; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030955945     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.155.5.9154867     Document Type: Article

References (37)

1. Repine, J. E. 1992. Scientific perspectives on adult respiratory distress syndrome. Lancet 339:466-469.
2. Jacobs, R. F., D. R. Tabor, A. W. Burks, and G. D. Campbell. 1989. Elevated interleukin-1 release by human alveolar macrophages during the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 140: 1686-1692.
3. Suter, P. M., S. Suter, E. Girardin, P. Roux-Lombard, G. E. Grau, and J. Dayer. 1992. High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis. Am. Rev. Respir. Dis. 145:1016-1022.
4. Leff, J. A., J. W. Baer, M. E. Bodman, J. M. Kirkman, P. F. Shanley, L. M. Patton, C. J. Beehler, J. M. McCord, and J. E. Repine. 1994. Interleukin-1-induced lung neutrophil accumulation and oxygen metabolite-mediated lung leak in rats. Am. J. Physiol. 266:L2-L8.
5. Donnelly, S. C., R. M. Strieter, S. L. Kunkel, A. Walz, C. R. Robertson, D. C. Carter, I. S. Grant, A. J. Pollok, and C. Haslett. 1993. Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups [see comments]. Lancet 341:643-647.
6. Koh, Y., B. M. Hybertson, E. K. Jepson, O. J. Cho, and J. E. Repine. 1995. Cytokine-induced neutrophil chemoattractant is necessary for interleukin-1-induced lung leak in rats. J. Appl. Physiol. 79:472-478.
7. Vadas, P., W. Pruzanski, E. Stefanski, L. G. Ellies, J. E. Aubin, A. Sos, and A. Melcher. 1991. Extracellular phospholipase A2 secretion is a common effector pathway of interleukin-1 and tumor necrosis factor action. Immunol. Lett. 28:187-193.
8. Canham, E. M., S. A. Shoemaker, R. M. Tate, R. N. Harada, I. F. McMurtry, and J. E. Repine. 1983. Mepacrine but not methylprednisolone decreases acute edematous lung injury after injection of phorbol myristate acetate in rabbits. Am. Rev. Respir. Dis. 127:594-598.
9. Katsumata, M., C. Gupta, and A. S. Goldman. 1986. A rapid assay for activity of phospholipase A2 using radioactive substrate. Anal. Biochem. 154:676-681.
10. Goldblum, S. E., K. M. Wu, and M. Jay. 1985. Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits. J. Appl. Physiol. 59: 1978-1985.
11. Wittwer, A. J., L. S. Carr, J. Zagorski, G. J. Dolecki, B. A. Crippes, and J. E. De Larco. 1993. High-level expression of cytokine-induced neutrophil chemoattractant (CINC) by a metastatic rat cell line: purification and production of blocking antibodies. J. Cell Physiol. 156:421-427.
12. Liau, D. F., C. R. Barrett, A. L. Bell, and S. F. Ryan. 1987. Functional abnormalities of lung surfactant in experimental acute alveolar injury in the dog. Am. Rev. Respir. Dis. 136:395-401.
13. Hess, H. H., and J. E. Derr. 1975. Assay of inorganic and organic phosphorus in the 0.1-5 nanomole range. Anal. Biochem. 63:607-613.
14. Corbet, A., J. Cregan, J. Frink, and A. J. Rudolph. 1983. Distention-produced phospholipid secretion in postmortem in situ lungs of newborn rabbits: inhibition by specific beta-adrenergic blockade. Am. Rev. Respir. Dis. 128:695-701.
15. Terada, L. S., D. M. Guidot, J. A. Leff, I. R. Willingham, M. E. Hanley, D. Piermattei, and J. E. Repine. 1992. Hypoxia injures endothelial cells by increasing endogenous xanthine oxidase activity. Proc. Natl. Acad. Sci. U.S.A. 89:3362-3366.
16. Shen, C. Y., D. Wang, M. L. Chang, and K. Hsu. 1995. Protective effect of mepacrine on hypoxia-reoxygenation-induced acute lung injury in rats. J. Appl. Physiol. 78:225-231.
17. Dana, R., H. L. Malech, and R. Levy. 1994. The requirement for phospholipase A2 for activation of the assembled NADPH oxidase in human neutrophils [published erratum appears in Biochem. J. 1994 Mar 15;298(Pt. 3):759]. Biochem. J. 297(Pt. 1):217-223.
18. van den Bosch, H. 1980. Intracellular phospholipases. Biochim. Biophys. Acta 604:191-246.
19. Bomalaski, J. S., and M. A. Clark. 1993. Phospholipase A2 and arthritis. Arthritis Rheum. 36:190-198.
20. Vadas, P., J. Browning, J. Edelson, and W. Pruzanski. 1993. Extracellular phospholipase A2 expression and inflammation: the relationship with associated disease states [Review]. J. Lipid Mediat. 8:1-30.
21. Cockcroft, S. 1992. G-protein-regulated phospholipases C, D and A2-mediated signalling in neutrophils. Biochim. Biophys. Acta 1113:135-160.
22. Yokote, K., N. Morisaki, M. Zenibayashi, S. Ueda, T. Kanzaki, Y. Saito, and S. Yoshida. 1993. The phospholipase-A2 reaction leads to increased monocyte adhesion of endothelial cells via the expression of adhesion molecules. Eur. J. Biochem. 217:723-729.
23. Rodewald, E., U. Tibes, G. Maass, and W. Scheuer. 1994. Induction of cytosolic phospholipase A2 in human leukocytes by lipopolysaccharide. Eur. J. Biochem. 223:743-749.
24. Mayer, R. J., and L. A. Marshall. 1993. New insights on mammalian phospholipase A2(s); comparison of arachidonoyl-selective and -non-selective enzymes. FASEB J. 7:339-348.
25. Forehand, J. R., R. B. Johnston, Jr., and J. S. Bomalaski. 1993. Phospholipase A2 activity in human neutrophils: stimulation by lipopolysaccharide and possible involvement in priming for an enhanced respiratory burst. J. Immunol. 151:4918-4925.
26. Pruzanski, W., P. Vadas, and J. Browning. 1993. Secretory non-pancreatic group II phospholipase A2: role in physiologic and inflammatory processes [Review]. J. Lipid Mediat. 8:161-167.
27. Holm, B. A., L. Keicher, M. Y. Liu, J. Sokolowski, and G. Enhorning. 1991. Inhibition of pulmonary surfactant function by phospholipases. J. Appl. Physiol. 71:317-321.
28. Goodman, R., T. M. Stevens, L. R. Mantegna, P. R. Kidd, R. R. Harris, and J. S. Kerr. 1991. Phospholipase A2 (PLA2) activity in bovine pulmonary artery endothelial cells. Agents Actions 34:113-116.
29. Pfeilschifler, J., C. Schalkwijk, V. A. Briner, and H. van den Bosch. 1993. Cytokine-stimulated secretion of group II phospholipase A2 by rat mesangial cells: its contribution to arachidonic acid release and prostaglandin synthesis by cultured rat glomerular cells. J. Clin. Invest. 92: 2516-2523.
30. Stevens, T. M., J. E. Chin, M. McGowen, J. Giannaras, and J. S. Kerr. 1989. Phospholipase A2 (PLA2) activity in rabbit chondrocytes. Agents Actions 27:385-387.
31. Ishida, H., H. Shinohara, Y. Amabe, H. Tojo, T. Nagata, and Y. Wakano. 1993. Effects of interleukin 1 beta, tumor necrosis factor alpha and transforming growth factor beta on group II phospholipase A2 activity in rat gingival fibroblasts. J. Periodontal Res. 28(6, Pt. 2):517-520.
32. Marshall, L. A., R. H. Hall, J. D. Winkler, A. Badger, B. Bolognese, A. Roshak, P. L. Flamberg, C. M. Sung, M. Fletcher-Chabot, J. L. Adams, and R. J. Mayer. 1995. SB 203347, an inhibitor of 14 kDa phospholipase A2, alters human neutrophil arachidonic acid release and metabolism and prolongs survival in murine endotoxin shock. J. Pharmacol. Exp. Ther. 274:1254-1262.
33. Leslie, C. C., D. R. Voelker, J. Y. Channon, M. M. Wall, and P. T. Zelarney. 1988. Properties and purification of an arachidonoyl-hydrolizing phospholipase A2 from a macrophage cell line, RAW 264.7. Biochim. Biophys. Acta 963:476-492.
34. Lin, L. L., A. Y. Lin, and D. L. DeWitt. 1992. Interleukin-1 alpha induces the accumulation of cytosolic phospholipase A2 and the release of prostaglandin E2 in human fibroblasts. J. Biol. Chem. 267:23451-23454.
35. Salgo, M. G., F. P. Corongiu, and A. Sevanian. 1993. Enhanced interfacial catalysis and hydrolytic specificity of phospholipase A2 toward peroxidized phosphatidylcholine vesicles. Arch. Biochem. Biophys. 304: 123-132.
36. Ohara, Y., T. E. Peterson, B. Zheng, J. F. Kuo, and D. G. Harrison. 1994. Lysophosphatidylcholine increases vascular superoxide anion production via protein kinase C activation. Arterioscler. Thromb. 14: 1007-1013.
37. Anderson, B. O., E. E. Moore, and A. Banerjee. 1994. Phospholipase A2 regulates critical inflammatory mediators of multiple organ failure [Review]. J. Surg. Res. 56:199-205.