Alterations affecting the p53 control pathway in bilharzial-related bladder cancer

Clinical Cancer Research

Volumn 3, Issue 4, 1997, Pages 531-536

  Osman, Iman ^a   Scher, Howard I ^a   Zhang, Zuo Feng ^a   Pellicer, Inmaculada ^a   Hamza, Reda ^b   Eissa, Saad ^b   Khaled, Hussin ^b   Cordon Cardo, Carlos ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADENOCARCINOMA; ADULT; AGED; APOPTOSIS; ARTICLE; BLADDER CANCER; BLADDER CARCINOMA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; SCHISTOSOMA; SQUAMOUS CELL CARCINOMA; TRANSITIONAL CELL CARCINOMA;

ADENOCARCINOMA; ADULT; AGED; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CARCINOMA, TRANSITIONAL CELL; CELL CYCLE; COHORT STUDIES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; EGYPT; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; HUMANS; IMMUNOPHENOTYPING; IN SITU NICK-END LABELING; INCIDENCE; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; SCHISTOSOMIASIS; URINARY BLADDER NEOPLASMS;

EID: 0030955673     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. El-Bolkainy, M. N., Mokhtar, N. M., Ghoniem, M. A., and Hussien, M. H. The impact of schistosomiasis on the pathology of bladder carcinoma. Cancer (Phila.), 48: 2643-2648, 1981.
2. Warren, W., Bigg, P. J., El-Baz, M., Ghoniem, M. A., Sttaton, M. R., and Venitt, S. Mutations in the p53 gene in schistosomal bladder cancer: a study of 92 tumors from Egyptian patients and comparison between mutational spectra from schistosomal and non-schistosomal urothelial tumors. Carcinogenesis (Lend.), 16: 1181-1189, 1995.
3. Vizcaino, A. P., Parkin, D. M., Boffeta, P., and Skinner, M. E. Bladder cancer: epidemiology and risk factors in Bulawayo, Zimbabwe. Cancer Causes & Control, 5: 517-522, 1994.
4. Khaled, H. M. Bladder cancer and Bilharziasis today. Cancer J., 6: 65-71, 1993.
5. El-Bolkainy, M. N., and Chu, E. W. Detection of Bladder Cancer Associated with Schistosomiasis. Cairo, Egypt: National Cancer Institute Cairo University, El Abram Press, 1981.
6. Raghavan, D., and Huben, R. Management of bladder cancer. Curr. Probl. Cancer, 19: 1-64, 1995.
7. Dalbagni, G., Presti, J., Reuter, V., Fair, W. R., and Cordon-Cardo, C. Genetic alterations in bladder cancer. Lancet, 324: 469-471, 1993.
8. Spruck, C. H., Ohneseit, P. E., Gonzalez-Zulueta, M., Esrig, D., Miyao, N., Tsai, Y. C., Lerner, S. P., Scnmutte, C., Yang, A. S., Cote, R., Dubeau, L., Nichols, P. W., Herman, G. G., Steven, K., Horn, T., Skinner, D. G., and Jones, P. A. Two molecular pathways to transitional cell carcinoma of the bladder, Cancer Res., 54: 784-788, 1994.
9. Cordon-Cardo, C., Dalbagni, D., Sarkis, A., and Reuter, V. E. Genetic alterations associated with bladder cancer. In: V. T. DeVita, S. Hellman, and S. A. J. B. Rosenberg (eds.), Important Advances in Oncology. Philadelphia: J. B. Lippincott Co., 1994.
10. Ramchurren, N., Cooper, K., and Summerhayes, K. Molecular events underlying schistosomiasis-related bladder cancer. Int. J. Cancer, 62: 237-244, 1995.
11. Gonzalez-Zulueta, M., Shibata, A., Ohneseit, P. F., Spruck, C. H., Busch, C., Shammer, M., Gibas, M., Nichols, P. W., Gonzalgo, M. L., Malmstrom, P. V., and Jones, P. A. High frequency of chromosome 9p allelic loss and CDKN2 tumor suppressor gene alterations in squamous cell carcinoma of the bladder. J. Natl. Cancer Inst., 87: 1383-1393, 1995.
12. Habuchi, T., Takahashi, R., Yamada, H., Ogawa, O., Kakehi, Y., Ogura, K., Hamzaki, S., Toguchida, J., Ishizaki, K., and Fujita, J. Influence of cigarette smoking and schistosomiasis on p53 gene mutation in urothelial cancer. Cancer Res., 53: 3794-3795, 1993.
13. Sarkis, A., Dalbagni, G., Cordon-Cardo, C., Sheinfeld, J., Herr, H., Zhang, Z. F., Fair, W. R., and Reuter, V. E. Detection of p53 mutations in superficial (T1) bladder carcinomas as a marker of disease progression. J. Natl. Cancer Inst., 55: 53-59, 1993.
14. Cordon-Cardo, C., Dalbagni, G., Saez, G. T., Oliva, M. R., Zhang, Z. F., Rosai, J., Reuter, V. E., and Pellicer, A. TP53 mutations in human bladder cancer: genotypic versus phenotypic patterns. Int. J. Cancer, 56: 347-353, 1994.
15. Fuks, Z., Persaud, R. S., Alfieri, A., McLoughlin, M., Ehleiter, D., Schwartz, J. L., Seddon, A., Cordon-Cardo, C., and Haimovitz-Friedman, A. Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo. Cancer Res., 54: 2582-2590, 1994.
16. Gavrili, V., Sherman, Y., and Ben-Sasson, S. A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol., 119: 493-501, 1992.
17. Metha, C. R., and Patel, N. R. A network algorithm for performing Fisher's exact test in rXc contingency tables. J. Am. Stat. Assoc., 78: 427-434, 1983.
18. Landis, R. J., Hetman, E. R., and Koch, G. G. Average partial association in three-way contingency tables: a review and discussion of alternative tests Int. Stat. Rev., 46: 237-254, 1978.
19. SAS/STAT User Guide. Version 6. Gary, NC: SAS Institute, Inc., 1990.
20. Fujimato, K., Yamada, Y., Okajima, E., Kakizoe, T., Sasaki, H., Sugimura, T., and Terada, M. Frequent association of p53 gene mutations in invasive bladder cancer. Cancer Res., 52: 1393-1398, 1992.
21. Lipponen, P. K. Overexpression of p53 nuclear oncoprotein in transitional bladder cancer and its prognostic value. Int. J. Cancer, 55: 365-370, 1993.
22. Esrig, D., Elmajian, D., Groshen, S., Freeman, J. A., Stein, J. P., Chen, S. C., Nichols, P. W., Skinner, D. G., Jones, P. A., and Cote, R. J. Accumulation of nuclear p53 and tumor progression in bladder cancer. N. Engl. J. Med., 19: 1259-1264, 1994.
23. Sarkis, A. S., Bajorin, D. F., Reuter, V. E., Herr, H. W., Netto, G., Zhang, Z. F., Schultz, P. K., Cordon-Cardo, C., and Scher, H. I. The prognostic value of p53 nuclear overexpression in patients with invasive bladder cancer treated with neoadjuvant M-VAC. J. Clin. Oncol., 13: 1384-1390, 1995.
24. Fakharzadeh, S. S., Trusko, S. P., and George, D. I. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J., 10: 1564-1569, 1991.
25. Momand, J., Zambetti, G. P., Olson, D. C., George, D. L., and Levine, A. J. The mdm2 oncogene products forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell, 69: 1237-1245, 1992.
26. Lianes, P., Orlow, I., Zhang, Z. F., Oliva, M., Sarkis, A., Reuter, V., and Cordon-Cardo, C. Altered patterns of MDM2 and TP53 expression in human bladder cancer. J. Natl. Cancer Inst., 86: 1325-1330, 1994.
27. Cordon-Cardo, C., Latres, E., Drobnjak, M., Oliva, M., Pollack, D., Woodruff, J. M., Marchai, V., Chen, J., Brennan, M. F., and Levine, A. J. Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res., 54: 794-799, 1994.
28. Girad, S. C., Cesarz, D., Fischer, V., and Krueger, G. R. Detection of p53 and mdm2 protein expression in head and neck carcinogenesis. Anticancer Res., 75: 1453-1457, 1995.
29. Zhang, H. Y., Xiong, Y., and Beach, D. Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes. Mol. Biol. Cell, 4: 897-906, 1993.
30. Michieli, P., Chedid, M., Lin, D., Pierce, J. H., Mercer, W. E., and Givo, D. Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Res., 54: 3391-3395, 1994.
31. Bathia, K., Fan, S., Spangler, G., Weintraub, M., O'Connor, P. M., Judde, J. G., and Magrath, I. A mutant p21 cyclin-dependent kinase inhibitor isolated from a Burkitt's lymphoma. Cancer Res., 55: 1431-1435, 1995.
32. Cordon-Cardo, C. Mutations of cell cycle regulators. Biological and clinical implications for human neoplasms. Am. J. Pathol., 147: 545-560, 1995.
33. Neal, D. E., Sharples, L., Smith, K., Kennelly, J., Hall, R. R., and Harris, A. L. The epidermal growth receptor and the prognosis of bladder cancer. Cancer (Phila.), 65: 1619-1623, 1990.
34. Neal, D. E., Sharpies, L., Smith, K., Kennelly, J., Hall, R. R., and Harris A. L. Epidermal growth factor receptor in human bladder cancer. Comparison of invasive and superficial tumors. Lancet, 1: 366-371, 1985.
35. Williams, B. O., Remington, L., Albert, D. M., Mukai, S., Bronson, R. T., and Jacks, T. Cooperative tumorigenic effects of germline mutations in Rb and p53. Nat. Genet., 7: 480-484, 1994.