Prevention of arterial thrombosis using a novel heparin with enhanced antiplatelet activity and reduced anticoagulant activity

Journal of Vascular Surgery

Volumn 26, Issue 3, 1997, Pages 366-372

  Poletti, L F ^a   Bird, K ^a   Harris, R B ^a   Marques, D ^a   Sobel, M ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; HEPARIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY INJURY; ARTERY THROMBOSIS; ARTICLE; CAROTID ARTERY FLOW; CONTROLLED STUDY; MALE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION; THROMBOSIS PREVENTION;

EID: 0030955366     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-5214(97)70029-6     Document Type: Article

References (26)

1. J. Hawiger Adhesive interactions of blood cells and the vascular wall RW Colman J Hirsh VJ Marder EW Salzman Hemostasis and thrombosis. 1994 J.B. Lippincott Philadelphia 762 796
2. JL. Moake Insolubilized von Willebrand factor and the initial events of hemostasis J Lab Clin Med 114 1989 1 3
3. JL Moake NA Turner NA Stathopolous L Nolasco JD. Hellums Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate, and is resistant to aspirin Blood 7 1988 1366 1374
4. JD Olson A Zaleski D Hermann PA. Flood Adhesion of platelets to purified solid-phase von Willebrand factor: effects of wall shear stress, ADP, thrombin, and ristocetin J Lab Clin Med 114 1989 6 18
5. R Moroose LW. Hoyer von Willebrand factor and platelet function Annu Rev Med 37 1986 157 163
6. L Badimon JJ Badimon J Rand VT Turitto V. Fuster Platelet deposition on von Willebrand factor-deficient vessels: extracorporeal perfusion studies in swine with von Willebrand's disease using native and heparinized blood J Lab Clin Med 110 1987 634 647
7. ZM. Ruggeri von Willebrand factor as a target for antithrombotic intervention Circulation 86 suppl III 1992 III26 III29
8. Y Ikeda M Handa K Kawano T Kamata M Murata Y Araki The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress J Clin Invest 87 1991 1234 1240
9. H Yamamoto M Nagano M Kitoh T Kobayashi R. Yoshimoto Monoclonal antibody against von Willebrand factor inhibits thrombus formation without prolongation of bleeding time [abstract] Blood 86 1995 84a
10. 2, an anti-guinea pig platelet glycoprotein Ib monoclonal antibody Arterioscler Thromb 11 1991 1231 1236
11. K Azzam LI Garfinkel C Bal dit Sollier M Cisse Thiam L. Drouet Antithrombotic effect of a recombinant von Willebrand factor, VCL, on nitrogen laser-induced thrombus formation in guinea pig mesenteric arteries Thromb Haemost 73 1995 318 323
12. M Sobel PM McNeill PL Carlson JC Kermode B Adelman R Conroy D. Marques Heparin inhibition of von Willebrand factor-dependent platelet function in vitro and in vivo J Clin Invest 87 1991 1787 1793
13. M Sobel D Soler J Kermode R. Harris Localization and characterization of a heparin binding domain peptide of human von Willebrand Factor J Biol Chem 267 1992 8857 8862
14. LF Poletti K Bird D Marques M. Sobel Structural aspects of heparin responsible for von Willebrand factor binding and inhibition of platelet agglutination [abstract] Circulation 94 1996 I743
15. M Sobel KE Bird R Tyler-Cross D Marques N Toma E Conrad RB. Harris Heparins designed to specifically inhibit platelet interactions with von Willebrand factor Circulation 93 1996 992 999
16. S Roux JP Carteaux P Hess L Falivene JP. Clozel Experimental thrombosis in the guinea pig Thromb Haemost 71 1994 252 256
17. JD. Folts An in-vivo model of experimental arterial stenosis, intimal damage and periodic thrombosis Circulation 83 suppl IV 1991 3 14
18. JP Carteaux A Gast TB Tschopp S. Roux Activated clotting time as an appropriate test to compare heparin and direct thrombin inhibitors such as hirudin or Ro 46-6240 in experimental arterial thrombosis Circulation 91 1995 1568 1574
19. VJ. Marder A simple technique for the measurement of plasma heparin concentration during anticoagulant therapy Thromb Diath Haemorrh 24 1970 230 239
20. BH Becker JL. Miller Effects of an antiplatelet glycoprotein Ib antibody on hemostatic function in the guinea pig Blood 74 1989 690 694
21. MA Howard BG. Firkin Ristocetin: a new tool in the investigation of platelet aggregation Thromb Haemost 26 1971 362 369
22. JG Kelton J Bishop CJ Carter J. Hirsh A comparison of the quantitative ristocetin von Willebrand factor assay by using fresh and fixed platelets Thromb Res 18 1980 477 483
23. JM Kupinski JL. Miller Identification of receptors for fibrinogen and von Willebrand factor mediating aggregation in guinea pig platelets Thromb Res 43 1986 335 344
24. JM Kupinski JL. Miller Synthesis by guinea pig megakaryocytes of platelet glycoprotein receptors for fibrinogen and von Willebrand factor Thromb Res 43 1986 345 352
25. SE Burke AM Lefer KC Nicolaou GM Smith B. Smith Responsiveness of platelets and coronary arteries from different species to synthetic thromboxane and prostaglandin endoperoxide analogues Br J Pharmacol 78 1983 287 292
26. HJ Weiss VT Turitto HR. Baumgartner Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate-dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndrome J Lab Clin Med 92 1978 750 764