Posttranscriptionally mediated decreases in folylpolyglutamate synthetase gene expression in some folate analogue-resistant variants of the L1210 cell: Evidence for an altered cognate mRNA in the variants affecting the rate of de novo synthesis of the enzyme

Journal of Biological Chemistry

Volumn 272, Issue 11, 1997, Pages 6903-6908

  Roy, Krishnendu ^a   Egan, Mary G ^a   Sirlin, Sonia ^a   Sirotnak, F M ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EDATREXATE; FOLIC ACID DERIVATIVE; FOLYLPOLYGLUTAMATE SYNTHASE; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME MODIFICATION; ENZYME SUBSTRATE; GENE EXPRESSION; LEUKEMIA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; RNA TRANSLATION;

AMINOPTERIN; ANIMALS; CELL LINE; DRUG RESISTANCE; FOLIC ACID ANTAGONISTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE SYNTHASES; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0030954945     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.11.6903     Document Type: Article

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