Human melanoma cells generate leukotrienes B4 and C4 from leukotriene A4

Archives of Dermatological Research

Volumn 289, Issue 6, 1997, Pages 347-351

  Okano Mitani, Hiroko ^a   Ikai, Kouichi ^a   Imamura, Sadao ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Human melanoma cell; Leukotriene A4 hydrolase; Leukotriene C4 synthase; LTB4; LTC4; LTD4

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; LEUKOTRIENE A4; LEUKOTRIENE A4 HYDROLASE; LEUKOTRIENE B4; LEUKOTRIENE C4;

ANIMAL EXPERIMENT; ARTICLE; FEMALE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

DINITROCHLOROBENZENE; ENZYME INHIBITORS; EPOXIDE HYDROLASES; ETHYLMALEIMIDE; GLUTATHIONE TRANSFERASE; HUMANS; INDOLES; LEUKOTRIENE A4; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENE D4; MELANOMA; MICROSOMES; TUMOR CELLS, CULTURED;

EID: 0030954212     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004030050203     Document Type: Article

References (42)

1. Abdel-Malek Z, Swope V, Doupnik C, Leikauf G, Nordlund JJ (1989) Responsiveness of malignant and normal melanocytes to autocrine eicosanoids. J Invest Dermutol 92 : 393
2. 4-methyl ester in mammalian skin. Biochem Pharmacol 44 : 2047-2053
3. 4. Br J Dermatol 114 : 409-412
4. 4. Clin Biochem 23:459-468
5. 4. J Invest Dermatol 106 : 162-167
6. 4. Br J Pharmacol 80 : 497-502
7. Carey TE, Takahashi T, Resnick LA, Oettgen HF, Old LJ (1976) Cell surface antigens of human malignant melanoma: mixed hemadsorption assays for humoral immunity to cultured autologous melanoma cells. Proc Natl Acad Sci USA 73 : 3278-3282
8. 4, and 12-hydroxy-eicosatetraenoic acid stimulate epidermal proliferation in vivo in the guinea pig. J Invest Dermatol 85 : 333-334
9. 4 by human erythrocytes. J Biol Chem 259 : 11403-11407
10. Fogh J, Wright WC, Loveless JD (1977) Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J Natl Cancer Inst 58 : 209-214
11. Ford-Hutchinson AW, Gresser M, Young RN (1994) 5-lipoxygenase. Annu Rev Biochem 63 : 383-417
12. Gillard J, Ford-Hutchinson AW, Chan C, Charleson S, Foster A, Fortin R, Leger S, McFarlane CS, Morton H, Piechuta H, Riendeau D, Rouzer CA, Rokach J, Young R, MacIntryre E, Eirmann G, Hopple S, Hupe L, Meurer R, Opas E, Pacholok S (1989) L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-y1]-2,2- dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor. Can J Physiol Pharmacol 67 : 456-464
13. 4/12-HETE binding sites in a human epidermal cell line. Prostaglandins 36 : 49-58
14. Henderson WR (1994) The role of leukotrienes in inflammation. Ann Intern Med 121 : 684-697
15. Ikai K, Imamura S (1993) Role of eicosanoids in the pathogenesis of atopic dermatitis. Prostaglandins Leukot Essent Fatty Acids 48 : 409-416
16. 4 hydrolase in human skin. J Invest Dermatol 102 : 253-257
17. 4 hydrolase activity in guinea pig. Biochem Biophys Res Commun 135 : 139-145
18. 4. Biochim Biophys Acta 959 : 305-315
19. 4. Eur J Biochem 196 : 395-400
20. Laemmli UK (1975) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 256 : 495-497
21. 4. Proc Natl Acad Sci USA 91 : 7663-7667
22. Lewis RA, Austen KF (1984) the biologically active leukotrienes. J Clin Invest 73 : 889-897
23. Lewis RA, Austen KF, Soberman RJ (1990) Leukotrienes and other products of the 5-lipoxygenase pathway. New Engl J Med 323 : 645-655
24. Lowry O, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193 : 265-275
25. 4 hydrolase gene but not the 5-lipoxygenase gene. Biochem Biophys Res Commun 161 : 740-745
26. Medrano EE, Farooqui JZ, Biossy RE, Biossy YL, Akadiri B, Nordlund JJ (1993) Chronic growth stimulation of human adult melanocytes by inflammatory mediators in vitro: implication for nevus formation and initial steps in melanocyte oncogenesis. Proc Natl Acad Sci USA 90 : 1790-1794
27. 4 binding site in cellular membranes. J Biol Chem 269 : 12816-12823
28. Morelli JG, Norris DA (1993) Influence of inflammatory mediators and cytokines on human melanocyte function. J Invest Dermatol 100 : 191s-195s
29. 4 as potent mitogens for cultured human neonatal melanocytes. J Invest Dermatol 93 : 719-722
30. 4-induced human melanocyte growth are inhibited by different isoquinolinesulfonamides. J Invest Dermatol 98 : 55-58
31. 4 and TGF-alfa are stimulators of human melanocyte migration in vitro. J Invest Dermatol 98 : 290-295
32. 4 hydrolase in guinea pig tissues. J Biol Chem 265 : 7520-7525
33. 4 hydrolase in the peripheral leukocytes of patients with atopic dermatitis. Arch Dermatol Res 288 : 168-172
34. Ruzicka T (1988) The physiology and pathophysiology of eicosanoids in the skin. Eicosanoids 1 : 59-72
35. Ruzicka T, Simmet T, Peskar BA, Ring J (1986) Skin levels of arachidonic acid-derived inflammatory mediators and histamine in atopic dermatitis and psoriasis. J Invest Dermatol 86 : 105-108
36. Sampson AP, Thomas RU, Costello JF (1992) Enhanced leukotriene synthesis in leukocytes of atopic and asthmatic subjects. Br J Clin Pharmacol 33 : 423-130
37. Samuelsson B (1983) Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 220 : 568-575
38. 4) in human skin. J Invest Dermatol 80 : 115-119
39. 2 stimulate normal human melanocytes in vitro: possible inducers of postinflamatory pigmentation. Tohoku J Exp Med 156 : 303-304
40. Tomita Y, Maeda K, Tagami H (1992) Melanocyte-stimulating properties of arachidonic acid metabolites: possible role in postinflammatory pigmentation. Pigment Cell Res 5 : 357-361
41. Towbin H, Staehlin T, Gordon J (1980) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 77 : 980-984
42. 4 synthase. Proc Natl Acad Sci USA 91 : 9745-9749