Effects of propofol on cerebral blood flow, metabolism, and cerebral autoregulation in the anesthetized pig

Journal of Neurosurgical Anesthesiology

Volumn 9, Issue 2, 1997, Pages 188-193

  Lagerkranser, Michael ^a   Stånge, Kristina ^a   Sollevi, Alf ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cerebral blood flow; Cerebral metabolic rate; Cerebral vascular reactivity; Propofol

Indexed keywords

PROPOFOL;

ANESTHESIA MECHANISM; ANIMAL EXPERIMENT; ARTICLE; AUTOREGULATION; BLOOD FLOW VELOCITY; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN OXYGEN CONSUMPTION; DRUG EFFECT; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; SWINE; VASOMOTOR REFLEX;

EID: 0030954201     PISSN: 08984921     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008506-199704000-00015     Document Type: Article

References (14)

1. Stephan H, Sonntag H, Schenk HD, et al. Effects of Disoprivan on cerebral blood flow, cerebral oxygen consumption, and cerebral vascular reactivity. Der Anaesthetist 1987;36:60-5.
2. Vandesteene A, Trempont V, Engelman E, et al. Effect of propofol on cerebral blood flow and metabolism in man. Anaesthesia 1988;43:42-3.
3. Van Hemelrijk J, Fitch W, Mattheussen M, et al. Effect of propofol on cerebral circulation and autoregulation in the baboon. Anesth Analg 1990;71:49-54.
4. Werner C, Hoffman WE, Kochs E, et al. The effects of propofol on cerebral and spinal cord blood flow in rats. Anesth Analg 1993;76:971-5.
5. Stånge K, Lagerkranser M, Sollevi A. Effect of adenosine-induced hypotension on the cerebral autoregulation in the anesthetized pig. Acta Anaesthesiol Scand 1989;33:450-7.
6. Olesen J. The effect of intracarotid epinephrine, norepinephrine, and angiotensin on the regional cerebral blood flow in man. Neurology 1972;22:978-87.
7. Stånge K, Lagerkranser M, Sollevi A. Effect of isoflurane-induced hypotension on cerebral autoregulation in the anesthetized pig. J Neurosurg Anesthesiol 1990;2:114-21.
8. Stånge K, Lagerkranser M, Sollevi A. Nitroprusside-induced hypotension and cerebrovascular autoregulation in the anesthetized pig. Anesth Analg 1991;73:745-52.
9. Stånge K, Lagerkranser M, Sollevi A. Nimodipine does not affect the cerebral autoregulatory response in the anesthetized pig. J Neurosurg Anesthesiol 1994;6:116-21.
10. Åkeson J, Messeter K, Rosén I, et al. Cerebral pharmacodynamics of anaesthetic and subanaesthetic doses of ketamine in the normoventilated pig. Acta Anaesthesiol Scand 1993;37:211-8.
11. Lundeen G, Manohar M, Parks C. Systemic distribution of blood flow in swine while awake and during 1.0 and 1.5 MAC isoflurane anesthesia with or without 50% nitrous oxide. Anesth Analg 1983;62:499-512.
12. Ramsey DE, Aldred N, Power JM. A simplified approach to the anesthesia of porcine laparoscopic surgical subjects. Lab Anim Sci 1993;43:336-7.
13. Cavazzutti M, Porro CA, Barbieri A, et al. Brain and spinal cord metabolic activity during propofol anaesthesia. Br J Anaesth 1991;66:490-5.
14. Artru AA, Shapira Y, Bowdle TA. Electroencephalogram, cerebral metabolic and vascular responses to propofol anesthesia in dogs. J Neurosurg Anesth 1992;4:99-109.