Morphological and morphometric analysis of serotonin-containing neurons in primary dissociated cultures of human rhombencephalon: A study of development

Developmental Brain Research

Volumn 99, Issue 2, 1997, Pages 243-252

  Levallois, Christine ^a   Valence, Corinne ^b   Baldet, Pierre ^c   Privat, Alain ^a  

^a INSTITUT CHARLES GERHARDT   (France)

^b CENTRE HOSPITALIER DE TROYES   (France)

^c GUI DE CHAULIAC HOSPITAL   (France)

Author keywords

cell differentiation; human rhombencephalon; morphological parameter; morphometric analysis; primary culture; serotonin neuron

Indexed keywords

1 (2 THIENYL)CYCLOHEXYLPIPERIDINE; GACYCLIDINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BRAIN DEVELOPMENT; CELL CULTURE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; FETUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MORPHOMETRICS; NORMAL HUMAN; PRIORITY JOURNAL; SEROTONINERGIC NERVE CELL;

CELL DIFFERENTIATION; CELL SIZE; CELLS, CULTURED; CYCLOHEXANES; CYCLOHEXENES; EXCITATORY AMINO ACID ANTAGONISTS; FETUS; HUMANS; NEURONS; NEUROPROTECTIVE AGENTS; PHENCYCLIDINE; PIPERIDINES; RECEPTORS, N-METHYL-D-ASPARTATE; RHOMBENCEPHALON; SEROTONIN; STREET DRUGS;

EID: 0030953875     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(97)00026-6     Document Type: Article

References (25)

1. Azmitia, E.C. and Gannon, P.J., The primate serotonergic system: a review of human and animal studies and a report on Macaca fascicularis. Advances in Neurology, Vol. 43, S. Fahn et al. (Ed.), Myoclonus, Raven, New York, 1986, pp. 407-468.
2. Bakay, R.A.E. and Sladek, J.R., Fetal tissue grafting into the central nervous system: yesterday, today and tomorrow, Neurosurgery, 33 (1993) 645-647.
3. Camu, W., Marlier, L., Lerner-Natoli, M., Rondouin, G. and Privat, A., Transplantation of serotonergic neurons into the 5,7-DHT-lesioned rat olfactory bulb restores the parameters of kindling, Brain Res., 518 (1990) 23-30.
4. Detta, A., Grabham, P. and Hitchcock, E., Phenotypic plasticity of mature human foetal mesenphephalic dopaminergic neurons and glial cells, Restor. Neurol. Neurosci., 4 (1992) 41-46.
5. Drian, M.J., Kamenka, J.M., Pirat, J.L and Privat, A., Non-competitive antagonists of N-methyl-D-aspartate prevent spontaneous death in primary culture of embryonic rat cortex, J. Neurosci. Res., 29 (1991) 133-138.
6. Freed, C.R., Breeze, R.E., Rosenberg, N.L., Schneck, S.A., Kriek, E., Qi, J.X., Lone, T., Zhang, Y.B, Snyder, J.A., Wells, T.H., Olson Ramig, L., Thompson, L., Mazziota, J.C., Huang, S.C., Grafton, S.T., Brooks, D., Sawle, G., Schroter, G. and Ansari, A.A., Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease. N. Engl. J. Med., 327 (1992) 1549-1555.
7. Féraboli-Lohnherr, D., Orsal, D., Yakovleff, A., Gimenez-Ribotta, M. and Privat, A., Recovery of locomotor activity in the adult chronic spinal rat after sublesional transplantation of embryonic nervous cells: specific role of serotonergic neurons, Dev. Brain Res., in press.
8. Frodl, E.M., Duan, W.M., Sauer, H., Kupsch, A. and Brundin, P., Human embryonic dopamine neurons xenografted to the rat: effects of cryopreservation and varying source of donor cells on transplant survival, morphology and function, Brain. Res., 647 (1994) 286-298.
9. Geny, C., Naimi-Sadaoui, S., Belkadi, A.E.M., Jeny, R., Kammoun, M. and Peschanski, M., Microglial chimaerism in human xenografts to the rat brain, Brain Res. Bull., 38 (1995) 383-391.
10. Granholm, A Ch., Gerhardt, G.A., Bygdeman, M. and Stromberg, I., Human fetal xenografts of brainstem tissue containing locus coeruleus neurons: functional and structural studies of intraocular grafts in athymic nude rats, Exp. Neurol., 118 (1992) 7-17.
11. Humpel, C., Bygdeman, M., Olson, L. and Stromberf, I., Human fetal neocortical tissue grafted to rat brain cavities survives, leads to reciprocical nerve fiber growth, and accumulates host Ig G, J. Comp. Neurol., 340 (1994) 337-348.
12. Kondoh, T., Pundt, L.L. and Low, W.C., Development of human ventral mesencephalic grafts in rats with 6-OHDA lesions of the nigrostriatal pathway, Neurosci. Res., 21 (1995) 223-233.
13. Levallois, C., Calvet, M.C., Kamenka, J.M., Petite, D. and Privat, A., TCP enhances the survival of human fetal spinal cord cells in culture, Brain Res., 573 (1992) 327-330.
14. Levallois, C., Calvet, M.C. and Petite, D., Immunocytochemical demonstration of monoamine-containing cells in human fetal brainstem dissociated cultures, Dev. Brain Res., 75 (1993) 141-145.
15. Levallois, C., Calvet, M.C, Petite, D. and Kamenka, J.M., Neuroprotective effect of N-methyl-D-aspartate non-competitive antagonists(arylcyclohexyl-amine derivatives) on human cultured spinal cord cells, Int. J. Dev. Neurosci., 12 (1994) 547-555.
16. Levallois, C., Calvet, M.C., Kamenka, J.M., Petite, D. and Privat, A., Primary dissociated cultures of human brainstem cells: a useful tool for their characterization and neuroprotection study, Cell Biol. Toxicol., 11 (1995) 155-160.
17. Lieth, E., Mcclay, D.R. and Lauder, J.M., Neuronal-glial interactions: complexity of neurite outgrowth correlates with substrate adhesivity of serotonergic neurons, Glia, 3 (1990) 169-179.
18. Lindvall, O., Brundin, P., Widner, H., Rehncrona, S., Gustavii, B., Frackowiak, R., Leenders, K.L., Swale, G., Rothwell, J.C. and Marsden, C.D., Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease, Science, 247 (1990) 574-577.
19. Nobin, A. and Bjorklund, A., Topography of the monoamine neuron systems in the human brain as revealed in fetuses, Acta Physiol. Scand., Suppl. 338 (1973) 259-282.
20. Privat, A., Mansour, H., Pavy, A., Geffard, M. and Sandillon, F., Transplantation of dissociated foetal serotonin neurons into the transected spinal cord of adult rats, Neurosci. Lett., 66 (1986) 61-66.
21. Rajaofetra, N., Poulat, P., Marlier, L., Drian, M.J, König, N., Geffard, M. and Privat, A., Fate of B1-B2 and B3 rhombencephalic cells transplanted into the transected spinal cord of adult rats: Light and electron microscopic studies, Exp. Neurol., 117 (1992) 59-70.
22. Sabate, O., Horellou, P., Vigne, E., Colin, P., Perricaudet, M., Buc-Caron, M.H. and Mallet, J., Transplantation to the rat brain of human neural progenitors that were genetically modified using adenoviruses, Nature Genet., 9 (1995) 256-260.
23. Sladek, J.R., Elsworth, J.D., Roth, R.H., Evans, L.E., Collier, T.J, Cooper, S.J., Taylor, J.R. and Redmond, D.E., J.R., Fetal dopamine cell survival after transplantation is dramatically improved at a critical donor gestational age in nonhuman primates, Exp. Neurol., 122 (1993) 16-27.
24. Suhr, S.T. and Gage, F.H., Gene therapy for neurologic disease, Arch. Neurol., 50 (1993) 1252-1268.
25. Sundström, E., Kolare, S., Souverbie, F., Samuelsson, E.B., Pschera, H., Lunell, N.O. and Seiger, A., Neurochemical differentiation of human bulbospinal monoaminergic neurons during the first trimester, Dev. Brain Res., 75 (1993) 1-12.