Molecular basis of autosomal dominant neurohypophyseal diabetes insipidus. Cellular toxicity caused by the accumulation of mutant vasopressin precursors within the endoplasmic reticulum

Journal of Clinical Investigation

Volumn 99, Issue 8, 1997, Pages 1897-1905

  Ito, Mika ^a   Jameson, J Larry ^a   Ito, Masafumi ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

autosomal dominant inheritance; endoplasmic reticulum; genetic mutation; neurohypophyseal diabetes insipidus; neuronal toxicity

Indexed keywords

ARGIPRESSIN; MUTANT PROTEIN; PROTEIN PRECURSOR; VASOPRESSIN;

ARTICLE; AUTOSOMAL DOMINANT DISORDER; CELL VIABILITY; CONTROLLED STUDY; DIABETES INSIPIDUS; ENDOPLASMIC RETICULUM; GENE MUTATION; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NEUROTOXICITY; PRIORITY JOURNAL;

EID: 0030953631     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119357     Document Type: Article

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