Oral administration of KW-5092, a novel gastroprokinetic agent with acetylcholinesterase inhibitory and acetylcholine release enhancing activities, causes a dose-dependent increase in the blood acetylcholine content of beagle dogs

Neuroscience Letters

Volumn 225, Issue 1, 1997, Pages 25-28

  Yamada, Shin ^a   Fujii, Takeshi ^a   Kawashima, Koichiro ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Acetylcholine; Beagle dog; Blood; KW 5092; Plasma; Radioimmunoassay

Indexed keywords

1 [2 [[[5 (PIPERIDINOMETHYL) 2 FURANYL]METHYL]AMINO]ETHYL] 2 IMIDAZOLIDINYLIDENEPROPANEDINITRILE FUMARATE; CHOLINESTERASE INHIBITOR;

ACETYLCHOLINE RELEASE; ADOLESCENT; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; FEMALE; GASTROINTESTINAL MOTILITY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RADIOIMMUNOASSAY;

ACETYLCHOLINE; ADMINISTRATION, ORAL; ANIMALS; CHOLINESTERASE INHIBITORS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; GASTROINTESTINAL AGENTS; GASTROINTESTINAL MOTILITY; IMIDAZOLES; NITRILES;

EID: 0030953490     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(97)00188-2     Document Type: Article

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