Synthesis and QSAR of some 3-amino-2-(substituted)aminomethyl-5,6-disubstituted thieno[2,3-d]pyrimidin-4(3N)-ones as novel H1-receptor antagonists

Drug Design and Discovery

Volumn 15, Issue 2, 1997, Pages 105-115

  Shishoo, Chamanlal J ^a   Shirsath, Vikas S ^a   Rathod, Ishwarsinh S ^a   Brahmbhatt, Samir B ^a   Pathak, Urvish S ^a   Jain, Kishor S ^a,b  

^a L M COLLEGE OF PHARMACY   (India)

^b R and D Core Healthcare Ltd   (India)

Author keywords

H1 antagonists; QSAR; Synthesis; Thieno 2,3 d pyrimidin 4(3H) ones

Indexed keywords

4 PYRIMIDINONE DERIVATIVE; ASTEMIZOLE; CETIRIZINE; DIPHENHYDRAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; LORATADINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; FEMALE; GUINEA PIG; ILEUM; LIPOPHILICITY; MALE; MOUSE; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR AFFINITY; SEDATION; STEREOCHEMISTRY;

ANIMALS; BLOOD PRESSURE; DOGS; FEMALE; GUINEA PIGS; HETEROCYCLIC COMPOUNDS, 2-RING; HISTAMINE H1 ANTAGONISTS; ILEUM; MALE; MICE; MOTOR ACTIVITY; MUSCLE CONTRACTION; PYRIMIDINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030953297     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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