Preliminary pharmacokinetic study of ibuprofen enantiomers after administration of a new oral formulation (ibuprofen arginine) to healthy male volunteers

Chirality

Volumn 9, Issue 3, 1997, Pages 297-302

  Fornasini, Gianfranco ^a   Monti, Nunzia ^a,c   Brogin, Giandomenico ^a   Gallina, Maddalena ^a   Eandi, Mario ^b   Persiani, Stefano ^a   Bani, Massimo ^a   Della Pepa, Carlo ^b   Zara, Gianpaolo ^b   Strolin Benedetti, Margherita ^a  

^a Zambon Group SpA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c IPAS SA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

IBUPROFEN; SPEDIFEN; UNCLASSIFIED DRUG;

ADULT; ANALGESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; ARGININE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-OVER STUDIES; DRUG COMBINATIONS; HALF-LIFE; HUMANS; IBUPROFEN; MALE; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

EID: 0030953064     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(1997)9:3<297::AID-CHIR16>3.0.CO;2-I     Document Type: Article

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