Ras1-mediated modulation of Drosophila homeotic function in cell and segment identity

Genetics

Volumn 146, Issue 2, 1997, Pages 619-628

  Boube, Muriel ^a   Benassayag, Corinne ^a   Seroude, Laurent ^b   Cribbs, David L ^a,c  

^a CBD CNRS   (France)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c Centre de Biologie du Développement Bâtiment 4R3   (France)

Author keywords

[No Author keywords available]

Indexed keywords

RAS PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; DROSOPHILA; FLY; GENE LOCUS; GENE MUTATION; HOMEOBOX; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BODY PATTERNING; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; GENES, INSECT; GENES, RAS; GTPASE-ACTIVATING PROTEINS; IN SITU HYBRIDIZATION; MUTATION; PHENOTYPE; PROTEINS; RAS GTPASE-ACTIVATING PROTEINS; RAS PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0030951951     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. BIGGS, W. H., K. H. ZAVITZ, B. DICKSON, A. V. D. STRATEN, D. BRUNNER et al., 1994 The Drosophila rolled locus encodes a MAP kinase required in the sevenless signal transduction pathway. EMBO J. 13: 1628-1635.
2. BOTAS, J., 1993 Control of morphogenesis and differentiation by HOM/Hox genes. Curr. Opin. Cell. Biol. 5: 1015-1022.
3. CAPOVILLA, M., M. BRANDT and J. BOTAS, 1994 Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis. Cell 76: 461-475.
4. CRIBBS, D. L., M. A. PULTZ, D. JOHNSON, M. MAZZULLA and T. C. KAUFMAN, 1992 Structural complexity and evolutionary conservation of the Drosophila homeotic gene proboscipedia. EMBO J. 11: 1437-1449.
5. CRIBBS, D. L., C. BENASSAYAG, F. M. RANDAZZO and T. C. KAUFMAN, 1995 Levels of homeotic protein function can determine developmental identity: evidence from low-level expression of the Drosophila homeotic gene proboscipedia under Hsp70 control. EMBO J. 14: 767-778.
6. DICKSON, B. J., A. V. D. STRATEN, M. DOMINGUEZ and E. HAFEN, 1996 Mutations modulating Raf signaling in Drosophila eye development. Genetics 142: 163-171.
7. GARCIA-BELLIDO, A., and E. B. LEWIS, 1976 Autonomous cellular differentiation of homoeotic bithorax mutants of Drosophila melanogaster. Dev. Biol. 48: 400-410.
8. GAUL, U., G. MARDON and G. M. RUBIN, 1992 A putative Ras GTPase activating protein acts as a negative regulator of signaling by the sevenless receptor tyrosine kinase. Cell 68: 1007-1019.
9. GEHRING, W. J., M. AFFOLTER and T. BŪRGLIN, 1994 Homeodomain proteins. Annu. Rev. Biochem. 63: 487-526.
10. GLISE, B., H. BOURBON and S. NOSELLI, 1995 hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement. Cell 83: 451-461.
11. Hou, X. S., T. CHOU, M. B. MELNICK and N. PERRIMON, 1995 The torso receptor tyrosine kinase can activate Raf in Ras-independent pathway. Cell 81: 63-71.
12. HUNTER, T., 1995 Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 80: 225-236.
13. IMMERGLUCK, K., P. A. LAWRENCE and M. BIENZ, 1990 Induction across germ layers in Drosophila mediated by a genetic cascade. Cell 62: 261-268.
14. KAUFMAN, T. C., 1978 Cytogenetic analysis of chromosome 3 in Drosophila melanogaster: isolation and characterization of four new alleles of the proboscipedia (pb) locus. Genetics 90: 579-596.
15. KEMPHUES, K. J., E. C. RAFF and T. C. KAUFMAN, 1983 Genetic analysis of B2t, the structural gene for a testis-specific beta-tubulin subunit in Drosophila melanogaster. Genetics 105: 345-356.
16. KENYON, C., 1994 If birds can fly, why can't we? Homeotic genes and evolution. Cell 78: 175-180.
17. LAWRENCE, P.A., and G. MORATA, 1994 Homeobox genes: their function in Drosophila segmentation and pattern formation. Cell 78: 181-189.
18. LINDSLEY, D. L., and G. G. ZIMM, 1992 The Genome of Drosophila melanogaster. Harcourt Brace Jovanovich, San Diego.
19. MALICKI, J., K. SCHUGHART and W. MCGINNIS, 1990 Mouse Hox-2.2 specifics thoracic segmental identity in Drosophila embryos and larvae. Cell 63: 961-967.
20. MCGINNIS, N., M. A. KUZIORA and W. MCGINNIS, 1990 Human Hox-4.2 and Drosophila deformed encode similar regulatory specificities in Drosophila embryos and larvae. Cell 63: 969-976.
21. MERRILL, V. K. L., F. R. TURNER and T. C. KAUFMAN, 1987 A genetic and developmental analysis of mutations in the deformed locus in Drosophila melanogaster. Dev. Biol. 122: 379-395.
22. MORATA, G., J. BOTAS, S. KERRIDGE and G. STRUHL, 1983 Homeotic transformations of the abdominal segments of Drosophila caused by breaking or deleting a central portion of the bithorax complex. J. Embryol. Exp. Morphol. 78: 319-341.
23. NEUMAN, S. F., E. SCHEJTER, F. M. HOFFMANN and B. Z. SHILO, 1984 The Drosophila ras oncogenes: structure and nucleotide sequence. Cell 37: 1027-1033.
24. PATTATUCCI, A., and T. C. KAUFMAN, 1991 The homeotic gene Sex combs reduced of Drosophila melanogaster is differentially regulated in the embryonic and imaginal stages of development. Genetics 129: 443-461.
25. PATTATUCCI, A., D. C. OTTESON and T. C. KAUFMAN, 1991 A functional and structural analysis of the Sex combs reduced locus of Drosophila melanogaster. Genetics 129: 423-441.
26. PERRIMON, N., 1994 Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila. Curr. Opin. Cell. Biol. 6: 260-266.
27. POPPERL, H., M. BIENZ, M. STUDER, S-K. CHAN, S. APARICIO et al., 1995 Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell 81: 1031-1042.
28. PULTZ, M. A., R. J. DIEDERICH, D. L. CRIBBS and T. C. KAUFMAN, 1988 The proboscipedia locus of the Antennapedia complex: a molecular and genetic analysis. Genes Dev. 2: 901-920.
29. RANDAZZO, F. M., D. L. CRIBBS and T. C. KAUFMAN, 1991 Rescue and regulation of proboscipedia: a homeotic gene of the Antennapedia Complex. Development 113: 257-271.
30. ROGGE, R., R. CAGAN, A. MAJUMDAR, T. DULANEY and U. BANERJEE, 1992 Neuronal development in the Drosophila retina: the sextra gene defines an inhibitory component in the developmental pathway of R7 photoreceptor cells. Proc. Nat. Acad. Sci. USA 89: 5271-5275.
31. SIMON, M. A., 1994 Signal transduction during the development of the Drosophila R7 photoreceptor. Dev. Biol. 166: 431-442.
32. SIMON, M. A., D. D. BOWTELL, G. S. DODSON, T. R. LAVERTY and G. M. RUBIN, 1991 Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67: 701-716.
33. STRUHL, G., 1981 A homeotic mutation transforming leg to antenna in Drosophila. Nature 292: 635-638.
34. TAUTZ, D., and C. PFEIFLE, 1989 A non radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98: 81-85.
35. TSUDA, L., Y. H. INOUE, M-A. Yoo, M. MIZUNO, M. HATA et al., 1993 A protein kinase similar to MAP kinase activator acts downstream of the Raf kinase in Drosophila. Cell 72: 407-414.
36. ZHAO, J. J., R. A. LAZZARINI and L. PICK, 1993 The mouse Hox-1.3 gene is functionally equivalent to the Drosophila Sex combs reduced gene. Genes Dev. 7: 343-354.