New benzocycloalkylpiperazines, potent and selective 5-HT(1A) receptor ligands

Journal of Medicinal Chemistry

Volumn 40, Issue 6, 1997, Pages 952-960

  Ahmad, Youssef El ^a   Laurent, Elisabeth ^a   Maillet, Philippe ^a   Talab, Akram ^a   Teste, Jean François ^a   Dokhan, Raymond ^b   Tran, Gilles ^a   Ollivier, Roland ^a  

^a Centre de Recherche   (France)

^b LDK France   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BUSPIRONE; CYCLOALKANE DERIVATIVE; FORSKOLIN; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; SEROTONIN; SEROTONIN 1A AGONIST;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY NEUROSIS; ARTICLE; DEPRESSION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; INSOMNIA; INTRAPERITONEAL DRUG ADMINISTRATION; LIMBIC SYSTEM; NONHUMAN; RECEPTOR AFFINITY;

ADENYLATE CYCLASE; ANIMALS; BEHAVIOR, ANIMAL; BINDING, COMPETITIVE; CYCLIC AMP; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; FORSKOLIN; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PIPERAZINES; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC; RECEPTORS, DOPAMINE; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030951765     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950759z     Document Type: Article

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