Bronchoalveolar macrophage CD14 expression: Shift between membrane- associated and soluble pools

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 272, Issue 5 16-5, 1997, Pages

  Hasday, Jeffrey D ^a,b   Dubin, Wendy ^a   Mongovin, Steven ^c,d   Goldblum, Simeon E ^a,b   Swoveland, Peggy ^b   Leturcq, Didier J ^e   Moriarty, Ann M ^e   Bleecker, Eugene R ^a,b   Martin, Thomas R ^c,d  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b BALTIMORE VA MEDICAL CENTER   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Bronchoalveolar lavage; Interleukin 4; Interleukin 6; Monocyte; Pulmonary

Indexed keywords

CD14 ANTIGEN; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE;

ANALYTIC METHOD; ANTIGEN EXPRESSION; ARTICLE; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; LUNG LAVAGE; MACROPHAGE ACTIVATION; MEMBRANE BINDING; MONOCYTE; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; SUPERNATANT;

EID: 0030951353     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1997.272.5.l925     Document Type: Article

References (44)

1. Aderka, D., J. Le, and J. Vilcek. IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice. J. Immunol. 143: 3517-3523, 1989.
2. Bazil, V., V. Horejsi, M. Baudys, H. Kristofova, J. L. Strominger, W. Kostka, and I. Hilgert. Biochemical characterization of a soluble form of the 53-kDa monocyte surface antigen. Eur. J. Immunol. 16: 1583-1589, 1986.
3. Bazil, V., and J. L. Strominger. Shedding as a mechanism of down-modulation of CD14 on stimulated human monocytes. J. Immunol. 147: 1567-1574, 1991.
4. Biondi, A., T. H. Rossing, J. Bennett, and R. F. I. Todd. Surface membrane heterogeneity among human mononuclear phagocytes. J. Immunol. 132: 1237-1243, 1984.
5. Boyum, A. Separation of leukocytes from blood and bone marrow. Scand. J. Clin. Invest 21, Suppl. 97: 77-89, 1968.
6. DeMarco, R., J. E. Ensor, and J. D. Hasday. Tumor-stimulated release of tumor necrosis factor-α by cultured human peripheral blood monocytes. Cell. Immunol. 140: 304-318, 1992.
7. Dentener, M. A., V. Bazil, E. J. U. Von Asmuth, M. Ceska, and W. A. Buurman. Involvement of CD14 in lipopolysaccharide-induced tumor necrosis factor-α, IL-6 and IL-8 release by human monocytes and alveolar macrophages. J. Immunol. 150: 2885-2891, 1993.
8. Dubin, W., T. R. Martin, P. Swoveland, D. J. Leturcq, A. M. Moriarty, P. S. Tobias, E. R. Bleecker, S. E. Goldblum, and J. D. Hasday. Asthma and endotoxin: lipopolysaccharide-binding protein and soluble CD14 in bronchoalveolar compartment. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L736-L744, 1996.
9. Essner, R., K. Rhoades, W. H. McBride, D. L. Morton, and J. S. Economou. IL-4 down-regulates IL-1 and TNF gene expression in human monocytes. J. Immunol. 142: 3857-3861, 1989.
10. Frey, E. A., D. S. Miller, J. Gullstein, A. Sundan, V. Bazil, T. Espevik, B. B. Finlay, and S. D. Wright. Soluble CD14 participates in the response of cells to lipopolysaccharide. J. Exp. Med. 176: 1665-1671, 1992.
11. Goldblum, S. E., T. W. Brann, X. Ding, J. Pugin, and P. S. Tobias. Lipopolysaccharide (LPS)-binding protein and soluble CD14 function as accessory molecules for LPS-induced changes in endothelial barrier function, in vitro. J. Clin. Invest. 93: 692-702, 1994.
12. Grunwald, U., C. Kruger, and C. Schutt. Endotoxin-neutralizing capacity of soluble CD14 is a highly conserved specific function. Circ. Shock 39: 220-225, 1993.
13. Hailman, E., H. S. Lichenstein, W. M. Wurfel, D. S. Miller, D. A. Johnson, M. Kelley, L. A. Busse, M. M. Zukowski, and S. D. Wright. Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14. J. Exp. Med. 179: 269-277, 1994.
14. Hance, A. J., S. Douches, R. J. Winchester, V. J. Ferrans, and R. G. Crystal. Characterization of mononuclear phagocyte subpopulations in the human lung by using monoclonal antibodies: changes in alveolar macrophage phenotype associated with pulmonary sarcoidosis. J. Immunol. 134: 284-292, 1985.
15. Haskill, S., C. Johnson, D. Eierman, S. Becker, and K. Warren. Adherence induces selective mRNA expression of monocyte mediators and proto-oncogenes. J. Immunol. 140: 1690-1694, 1988.
16. Haziot, A., S. Chen, E. Ferrero, M. G. Low, R. Silber, and G. Goyert. The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage. J. Immunol. 141: 547-552, 1988.
17. Haziot, A., G.-W. Rong, J. Silver, and S. M. Goyert. Recombinant soluble CD14 mediates the activation of endothelial cells by lipopolysaccharide. J. Immunol. 151: 1500-1507, 1993.
18. Heumann, D., P. Gallay, C. Barras, P. Zaech, R. J. Ulevitch, P. S. Tobias, M.-P. Glauser, and J. D. Baumgartner. Control of lipopolysaccharide (LPS) binding and LPS-induced tumor necrosis factor secretion in human peripheral blood monocytes. J. Immunol. 148: 3503-3512, 1992.
19. Ikewaki, N., and H. Inoko. Induction of CD14 antigen on the surface of U937 cells by an interleukin-6 autocrine mechanism after culture with formalin-killed gram negative bacteria. Tissue Antigens 38: 117-123, 1991.
20. Landmann, R., A. E. Fisscher, and J.-P. Obrecht. Interferon-γ and interleukin-4 down-regulate soluble CD14 release in human monocytes and macropahges. J. Leukocyte Biol. 52: 323-330, 1992.
21. Landmann, R., C. Ludwig, R. Obist, and J. P. Obrecht. Effect of cytokines and lipopolysaccharide on CD14 antigen expression in human monocytes and macrophages. J. Cell. Biochem. 47: 317-329, 1991.
22. Lauener, R. P., S. M. Goyert, R. S. Geha, and D. Vercelli. Interleukin 4 down-regulates the expression of CD14 in normal human monocytes. Eur. J. Immunol. 20: 2375-2381, 1990.
23. Marchant, A., J. Duchow, J.-P. Delville, and M. Goldman. Lipopolysaccharide induces up-regulation of CD14 molecule on monocytes in human whole blood. Eur. J. Immunol. 22: 1663-1665, 1992.
24. Martin, T. R., J. C. Mathison, P. S. Tobias, D. J. Leturcq, A. M. Moriarty, R. J. Maunder, and R. J. Ulevitch. Lipopolysaccharide binding protein enhances the responsiveness of alveolar macrophages to bacterial lipopolysaccharide. J. Clin. Invest. 90: 2209-2219, 1992.
25. Martin, T. R., S. M. Mongovin, P. S. Tobias, J. C. Mathison, A. M. Moriarty, D. J. Leturcq, and R. J. Ulevitch. The CD14 differentiation antigen mediates the development of endotoxin responsiveness during differentiation of mononuclear phagocytes. J. Leukocyte Biol. 56: 1-9, 1994.
26. Martin, T. R., G. Rubenfeld, K. P. Steinberg, L. D. Hudson, G. Raghu, A. M. Moriarty, P. S. Tobias, and R. J. Ulevitch. Endotoxin, endotoxin-binding protein, and soluble CD14 are present in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome. Chest 105: 55S-56S, 1994.
27. Meltzer, S., J. D. Hasday, P. Wisniewski, K. A. McCrea, M. Johns, E. Rechsteiner, and E. R. Bleecker. Effects of ragweed allergen on peripheral airway resistance, cellular responses and cytokines in asthma (Abstract). Am. J. Respir. Crit. Care Med. 149: A962, 1994.
28. Michel, O., R. Ginanni, J. Duchateau, F. Vertongen, B. Le Bon, and R. Sergysels. Domestic endotoxin exposure and clinical severity of asthma. Clin. Exp. Allergy 21: 441-448, 1991.
29. 2-terminal sequence of a plasmacytoma growth factor derived from the murine macrophage cell line P3888D1. J. Immunol. 139: 813-817, 1987.
30. Parsons, P. E., G. S. Worthen, E. E. Moore, R. M. Tate, and P. M. Henson. The association of circulating endotoxin with the development of the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 140: 294-301, 1989.
31. Payne, J. B., F. C. Nichol, and J. F. Peluso. The effects of interfeonγ and bacterial lipopolysaccharide on CD14 expression in human monocytes. J. Interferon Res. 12: 307-310, 1992.
32. Pugin, J., C.-C. Schurer, D. Leturcq, A. Moriarty, R. J. Ulevitch, and P. S. Tobias. Lipopolysaccharide activation of ' human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. Proc. Natl. Acad. Sci. USA 90: 2744-2748, 1994.
33. Ruppert, J., D. Friedrichs, J. Xu, and H. Peters. IL-4 decreases the expression of the monocyte differentiation marker CD14, paralleled by an increasing accessory pathway. Immunobiology 182: 449-464, 1991.
34. Rylander, R., P. Hagland, and M. Lundholm. Endotoxin in cotton dust and respiratory function decrement among cotton workers in an experimental cardroom. Am. Rev. Respir. Dis. 131: 209-213, 1985.
35. Sandstrom, T., L. Bjermer, and R. Rylander. Lipopolysaccharide (LPS) inhalation in healthy subjects causes bronchoalveolar neutrophilia, lymphocytosis, and fibronectin increase. Am. J. Ind. Med. 25: 103-104, 1994.
36. Schutt, C., T. Schilling, and C. Kruger. sCD14 prevents endotoxin inducible oxidative burst response in human monocytes. Allerg. Immunol. 37: 159-164, 1991.
37. Striz, I., L. Zheng, Y. M. Wang, H. Pokorna, P. C. Bauer, and U. Costabel. Soluble CD14 is increased in bronchoalveolar lavage of active sarcoidosis and correlates with alveolar macrophage membrane-bound CD14. Am. J. Respir. Crit. Care Med. 151: 544-547, 1995.
38. Tobias, P. S., J. Mathison, D. Mintz, J.-D. Lee, V. Kravchenko, K. Kato, J. Pugin, and R. J. Ulevitch. Participation of lipopolysaccharide-binding protein in lipopolysaccharide-dependent macrophage activation. Am. J. Respir. Cell Mol. Biol. 7: 239-245, 1992.
39. Tobias, P. S., K. Soldau, and R. J. Ulevitch. Isolation of a lipopolysaccharide-binding protein acute phase reactant from rabbit serum. J. Exp. Med. 164: 777-793, 1986.
40. Ulich, T. R., L. R. Watson, S. Yin, K. Guo, P. Wang, H. Thang, and J. del Castillo. The intratracheal administration of endotoxin and cytokines. I. Characterization of LPS-induced IL-1 and TNF mRNA expression and the LPS-, IL-1-, and TNF-induced inflammatory infiltrate. Am. J. Pathol. 138: 1485-1496, 1991.
41. Von Wichert, P. V., K. Joseph, B. Muller, and W. M. Franck. Quantitation of intraalveolar fluid. Am. Rev. Respir. Dis. 147: 148-152, 1993.
42. Walker, C., W. Bauer, R. K. Braun, G. Menz, P. Braun, F. Schwarz, T. T. Hansel, and B. Villiger. Activated T cells and cytokins in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia. Am. J. Respir. Crit. Care Med. 150: 1038-1048, 1994.
43. Walker, C., E. Bode, L. Boer, T. T. Hansel, K. Blaser, and J.-C. J. Virchow. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am. Rev. Respir. Dis. 146: 109-115, 1992.
44. Wright, S. D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249: 1431-1433, 1990.