Oral teratology studies with meloxicam in rabbits

Pharmacometrics

Volumn 53, Issue 1, 1997, Pages 87-95

  Matsuo, Asaki ^a   Nishimura, Michiyo ^a   Lehmann, Horst ^b   Katsuki, Shoji ^a  

^a NIPPON BOEHRINGER INGELHEIM CO LTD   (Japan)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

(rabbit); anti inflammatory drug (NSAID); Meloxicam; Nonsteroida; Reproduction; Teratogenicity

Indexed keywords

MELOXICAM; NONSTEROID ANTIINFLAMMATORY AGENT; UH AC 62XX; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIGESTIVE SYSTEM ULCER; DOSE RESPONSE; EMBRYOTOXICITY; FEMALE; FETUS WASTAGE; NONHUMAN; ORAL DRUG ADMINISTRATION; PREGNANCY COMPLICATION; RABBIT; TERATOLOGY; WEIGHT GAIN;

EID: 0030951110     PISSN: 03008533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Lehmann, H. and Niggeschulze, A. (1971): The teratologic effects of Thalidomide in Himalayan rabbits, Tax. appl. PharmacoL, 18, 208-219.
2. Lehmann, H., Matsuo, A., Niggeschulze, A. and Kast, A. (1986): Litter parameters and spontaneous abnormalities in Himalayan rabbits, Exp. Anim., 35, 321-328.
3. Sokol, R.R. and Rohlf, F.J. (1969): Biometry, The principles and practice of statistics in biological research. W.H. Freeman and Company, San Francisco, p. 585-601.
4. Wilson, J. (1965): Methods for administering agents and detecting malformations in experimental animals. Teratology ; Principles and techniques, (Wilson, J. and Warkany, J. ed.), University of Chicago Press, Chicago, pp. 262-277.