The role of liver and kidney on the pharmacokinetics of a recombinant amino terminal fragment of bactericidal/permeability-increasing protein in rats

Pharmaceutical Research

Volumn 14, Issue 2, 1997, Pages 224-229

  Bauer, Robert J ^a   Der, Kenneth ^b   Ottah Ihejeto, Nneka ^d   Barrientos, Jennifer ^a   Kung, Ada H C ^c  

^a XOMA Corporation   (United States)

^b Arris Pharmaceutical Corporation   (United States)

^c Sky Line Technol Consult Grp I   (United States)

^d NONE

Author keywords

Bactericidal permeability incrasing protein; Heparin; Kidney; Liver; Pharmacokinetics

Indexed keywords

BACTERICIDAL PERMEABILITY INCREASING PROTEIN; HEPARIN; RECOMBINANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG STABILITY; DRUG TISSUE LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FIRST PASS EFFECT; HEART RIGHT ATRIUM; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY; LIVER; LUNG; MALE; MATHEMATICAL MODEL; NEPHRECTOMY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; HEPARIN; KIDNEY; LIVER; LUNG; MALE; MEMBRANE PROTEINS; RATS; RECOMBINANT PROTEINS;

EID: 0030951011     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012013113759     Document Type: Article

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