Influence of gentamicin dosing interval on the efficacy of penicillin-containing regimens in experimental Enterococcus faecalis endocarditis

Journal of Antimicrobial Chemotherapy

Volumn 39, Issue 4, 1997, Pages 519-522

  Marangos, Markos N ^a,d   Nicolau, Bt David P ^a,b   Quintillani, Richard ^a,c   Nightingale, Charles H ^a,b  

^a HARTFORD HOSPITAL   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^d MAINE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENTAMICIN; PENICILLIN G;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL COUNT; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; ENDOCARDITIS; ENTEROCOCCUS FAECALIS; EXPERIMENTAL INFECTION; INTRAMUSCULAR DRUG ADMINISTRATION; NONHUMAN; RABBIT;

EID: 0030951010     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/39.4.519     Document Type: Article

References (7)

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2. Hitt, C. M., Patel, K. B., Nicolau, D. P., Nightingale, C. H. & Quintiliani, R. (1994). Effects of piperacillin/tazobactam on once-daily gentamicin pharmacokinetics. In Program and Abstracts of the Twenty-Ninth Annual Midyear Clinical Meeting, Orlando, FL, 1994. Abstract P473E, p. 2267. American Society of Hospital Pharmacists, Bethesda, MD.
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6. Carrizosa, J. & Levison, M. E. (1981). Minimal concentrations of aminoglycoside that can synergize with penicillin in enterococcal endocarditis. Antimicrobial Agents and Chemotherapy 20, 405-9.
7. Miller, M. M., El-Sohkary, M. A., Feinstein, S. A. & Lowy, F. D. (1986). Penicillin-induced effect on streptomycin uptake and early bactericidal activity differ in viridans group and streptococci. Antimicrobial Agents and Chemotherapy 30, 763-68.