17β-(3-Furyl)-5β-androstane-3β-14β,17α-triol (PST 2238). A very potent antihypertensive agent with a novel mechanism of action

Journal of Medicinal Chemistry

Volumn 40, Issue 11, 1997, Pages 1561-1564

  Quadri, Luisa ^a   Bianchi, Giuseppe ^b   Cerri, Alberto ^a   Fedrizzi, Giorgio ^a   Ferrari, Patrizia ^a   Gobbini, Mauro ^a   Melloni, Piero ^a   Sputore, Simona ^a   Torri, Marco ^a  

^a Prassis Ist di Ricerche Sigma Tau ^*  (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

17BETA (3 FURYL) 5BETA ANDROSTANE 3BETA,14BETA,17ALPHA TRIOL; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE INHIBITOR; ANDROSTANE DERIVATIVE; ANTIHYPERTENSIVE AGENT; OUABAIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; ESSENTIAL HYPERTENSION; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT;

ANDROSTANOLS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; ENZYME INHIBITORS; HYPERTENSION; KINETICS; MOLECULAR STRUCTURE; NA(+)-K(+)-EXCHANGING ATPASE; OUABAIN; RATS; RATS, MUTANT STRAINS;

EID: 0030950682     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970162e     Document Type: Article

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