Mitral valve prolapse and ventricular arrhythmias: Observations in a patient with a 20-year history

Journal of Cardiovascular Electrophysiology

Volumn 8, Issue 3, 1997, Pages 307-316

  Wilde, Arthur A M ^a   Düren, Donald R ^a   Hauer, Richard N W ^b   DeBakker, Jacques M T ^a   Bakker, Patricia F A ^b   Becker, Anton E ^a   Janse, Michiel J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

delayed afterdepolarization; electrophysiology; flunarizine; triggered activity; ventricular fibrillation; ventricular tachycardia

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; PHENYTOIN;

ADULT; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; CASE REPORT; CLINICAL FEATURE; HEART DEPOLARIZATION; HEART ELECTROPHYSIOLOGY; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HUMAN; MALE; MITRAL VALVE PROLAPSE; PRIORITY JOURNAL; REENTRY ARRHYTHMIA;

EID: 0030950164     PISSN: 10453873     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1540-8167.1997.tb00793.x     Document Type: Article

References (29)

1. Hancock EW, Cohn K: The syndrome associated with midsystolic click and late systolic murmur. Am J Med 1966;41:183-196.
2. Engel TR, Meister SG, Frankl WS: Ventricular extrastimulation in the mitral valve prolapse syndrome: Evidence for ventricular reentry. J Electrocardiol 1978;11:137-142.
3. Fauchier JP, Neel Ch, Charbonnier B, et al: Les troubles du rythme du prolapsus mitral. Ann Cardiol Angélol 1980;29:281-290.
4. Leclercq JF, Malerque MC, Milosevic D, et al: Troubles du rythme ventriculaires et prolapsus mitral. Arch Mal Coeur 1980;3:276-287.
5. Rahilly GT, Prystowsky EN, Zipes DP, et al: Clinical electrophysiologic findings in patients with repetitive monomorphic ventricular tachycardia and otherwise normal electrocardiogram. Am J Cardiol 1982;50:459-468.
6. Shenoy MM, Hariman RJ, Balla S, et al: Triggered activity as a possible mechanism of ventricular tachycardia in mitral valve prolapse. Am Heart J 1986;112: 1339-1340.
7. Vos MA, Gorgels APM, Leunissen JDM, et al: Flunarizine allows differentiation between mechanisms of arrhythmias in the intact heart. Circulation 1990;81:343-349.
8. Park JK, Danilo P, Rosen MR: Effects of flunarizine on impulse initiation in canine Purkinje fibers. J Cardiovasc Electrophysiol 1992;3:306-314.
9. Sippens Groenewegen A, Spekhorst H, Van Hemel NM, et al: Body surface mapping of ectopic left and right ventricular activation: QRS spectrum in patients without structural heart disease. Circulation 1990;82: 879-896.
10. De Bakker JMT, van Capelle FJL, Janse MJ, et al: Slow conduction in the infarcted human heart: "Zigzag" course of activation. Circulation 1993;88: 915-926.
11. Savage DD, Levy D, Garrison RJ, et al: Mitral valve prolapse in the general population. 3 Dysrhythmias: The Framingham study. Am Heart J 1983;106:582-586.
12. Duren DR, Becker AE, Dunning AJ: Long-term follow-up of idiopathic mitral valve prolapse in 300 patients: A prospective study. J Am Coll Cardiol 1988; 11:42-47.
13. Zabel M, Koller B, Franz MR: Amplitude and polarity of stretch-induced voltage changes depend on the timing of stretch: A means to characterize stretch-activated channels in the intact heart. (Abstract) PACE 1993;16:886.
14. Lab MJ: Mechanically dependent changes in action potentials from the intact frog ventricle. Circ Res 1978;42:519-528.
15. Von Wagoner DR: Mechanosensitive gating of atrial ATP sensitive potassium channels. Circ Res 1993;72: 973-983.
16. Criley JM, Zeilenga DW, Morgan MT: Mitral dysfunction: A possible cause of arrhythmias in the prolapsing mitral leaflet syndrome. Trans Am Clin Clim Assoc 1973;85:44-53.
17. Hansen DE, Craig CS, Hondeghem LM: Stretch-induced arrhythmias in the isolated canine ventricle: Evidence for the importance of mechanoelectrical feedback. Circulation 1990;81:1094-1105.
18. Wang Z, Taylor K, Denney WD, et al: Initiation of ventricular extrasystoles by myocardial stretch in chronically dilated and failing canine left ventricle. Circulation 1994;90:2022-2031.
19. Bluschke V, Köhler E, Seipel L, et al: Arrhythmien beim Mitralklappenprolapssyndrom. Z Kardiol 1979; 68:396-403.
20. Zuppiroli A, Mori F, Favilli S, et al: Arrhythmias in mitral valve prolapse: Relation to anterior mitral valve leaflet thickening, clinical variables, and color Doppler echocardiographic parameters. Am Heart J 1994;128: 919-927.
21. Cobbs BW, King SB: Ventricular buckling: A factor in the abnormal ventriculogram and peculiar hemodynamics associated with mitral valve prolapse. Am Heart J 1977;93:741-758.
22. Lichstein E: Site of origin of ventricular premature beats in patients with mitral valve prolapse. Am Heart J 1980;100:450-457.
23. Pitcher DW, Curry PVL, O'Keefe DB, et al: Sites of origin and behaviour of arrhythmias in mitral valve prolapse: Assessment using simultaneous 12 lead electrocardiography. (Abstract) Br Heart J 1980;43:117.
24. Muilwijk SLC, Wilde AAM, Sippens Groenewegen A, et al: Identification of the site of origin of ventricular arrhythmias accompanying mitral valve prolapse using body surface mapping. (Abstract) Eur Heart J 1994; 15(Abstr Suppl):185.
25. De Bakker JMT, Coronel R, Tasseron S, et al: Ventricular tachycardia in the infarcted, Langendorff-perfused human heart: Role of the arrangement of surviving cardiac fibers. J Am Coll Cardiol 1990;15:1594-1607.
26. Gorgels A, Vos M, Smeets J, et al: Use of flunarizine to identify triggered activity as a mechanism of clinical arrhythmias. (Abstract) Eur Heart J 1991;12(Abstr Suppl):44.
27. Morady F, Shen E, Bhandari A, et al: Programmed ventricular stimulation in mitral valve prolapse: Analysis of 36 patients. Am J Cardiol 1984;53:135-138.
28. Rosenthal ME, Hamer A, Gang ES, et al: The yield of programmed ventricular stimulation in mitral valve prolapse patients with ventricular arrhythmias. Am Heart J 1985;110:970-976.
29. Brugada P, Green M, Abdollah H, et al: Significance of ventricular arrhythmias initiated by programmed ventricular stimulation: the importance of the type of ventricular arrhythmia induced and the number of premature stimuli required. Circulation 1984;69:87-92.