Targeting naproxen to non-parenchymal liver cells protects against endotoxin induced liver damage

Journal of Drug Targeting

Volumn 4, Issue 5, 1997, Pages 303-310

  Lebbe, C ^a   Reichen, J ^a   Wartna, E ^b   Sagesser H ^a   Poelstra, K ^b   Meijer, D K F ^b  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Cholestasis; Hepatotoxicity; Kupffer cells; Non steroidal antiinflammatory drugs; Prostaglandins; Sinusoidal endothelial cells

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; ENDOTOXIN; HUMAN SERUM ALBUMIN; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTASIS; CONTROLLED STUDY; DRUG CONJUGATION; DRUG EFFECT; DRUG TARGETING; ENZYME RELEASE; INTRAVENOUS DRUG ADMINISTRATION; ISOLATED LIVER; KIDNEY DISEASE; KUPFFER CELL; LIVER CELL; LIVER DISEASE; LIVER PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROPIONIBACTERIUM ACNES; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS INHIBITION; RAT; VASCULAR RESISTANCE;

EID: 0030949988     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611869708995846     Document Type: Article

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