Signal transduction and gene expression in the eye: A contemporary view of the pro-inflammatory, anti-inflammatory and modulatory roles of prostaglandins and other bioactive lipids

Survey of Ophthalmology

Volumn 41, Issue SUPPL. 2, 1997, Pages

  Bazan, N G ^a   Allan, G ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

corneal wound healing; excitoxicity; glaucoma; metalloproteinases; ocular inflammation; oxidative stress; phospholipase A2; platelet activating factor

Indexed keywords

6 (2 CHLOROPHENYL) 4,7,8,10 TETRAHYDRO 9 (4 METHOXYPHENYLCARBAMOYL) 1 METHYLPYRIDO[4',3':4,5]THIENO[3,2 F][1,2,4]TRIAZOLO[4,3 A][1,4]DIAZEPINE; APAFANT; BN 50726; BN 50727; CYTOCHROME P450; GINKGOLIDE B; ICOSANOID; LIPOXYGENASE; MEMBRANE PHOSPHOLIPID; METALLOPROTEINASE; PHOSPHOLIPASE A2; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANTERIOR EYE SEGMENT; ANTIINFLAMMATORY ACTIVITY; ARACHIDONIC ACID METABOLISM; CONFERENCE PAPER; CORNEA EPITHELIUM; EXTRACELLULAR MATRIX; EYE INFLAMMATION; EYE IRRITATION; GENE EXPRESSION; GLAUCOMA; HUMAN; INTRAOCULAR PRESSURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SECOND MESSENGER; SIGNAL TRANSDUCTION; SUBCONJUNCTIVAL DRUG ADMINISTRATION; TOPICAL DRUG ADMINISTRATION; WOUND HEALING;

EID: 0030949887     PISSN: 00396257     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0039-6257(97)80004-5     Document Type: Conference Paper

References (106)

1. PA Abrahamsohn TM Zorn Implantation and decidualization in rodents J Exp Zool 266 1993 603 628
2. PD Allen SA Bustin AC Newland The role of apoptosis (programmed cell death) in haemopoiesis and the immune system Blood Rev 7 1993 63 73
3. JA Angerman-Stewart TE Eling WC Glasgow Prostaglandin H synthase-2 is induced in Syrian hamster embryo cells in response to basic fibroblast growth factor Arch Biochem Biophys 318 1995 378 386
4. S Arias-Negrete K Keller K Chadee Proinflammatory cytokines regulate cyclooxygenase-2 mRNA expression in human macrophages Biochem Biophys Res Commun 208 1995 582 589
5. NG Bazan The metabolism of omega-3 polyunsaturated fatty acids in the eye: the possible role of docosahxaenoic acid and docosanoids in retinal physiology and ocular pathophysiology LZ Bito J Stjernschantz The Ocular Effects of Prostaglandins and Other Eicosanoids 1989 Allan R. Liss Inc New York 95 112
6. NG Bazan BS Fletcher HR Herschman PK Mukherjee Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene Proc Natl Acad Sci 91 1994 5252 5256
7. NG Bazan Inflammation: A signal terminator Nature 374 1995 501 502
8. HEP Bazan DL Birkle R Beuerman NG Bazan Cryogenic injury alters the metabolism of AA in rabbit corneal layers Invest Ophthalmol Vis Sci 26 1985 474 480
9. HEP Bazan DL Birkle R Beuerman NG Bazan Inflammation-induced stimulation of the synthesis ofprostaglandins and lipoxygenase products in rabbit cornea Curr Eye Res 4 1985 175 179
10. NG Bazan BS Fletcher HR Herschman PK Mukheljee Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene Proc Natl Acad Sci USA 91 1994 5252 5256
11. HEP Bazan ST Reddy N Lin Platelet-activating factor (PAF) accumulation correlates with injury in the cornea Exp Eye Res 52 1991 481 491
12. HEP Bazan Y Tao NG Bazan Platelet activating factor induces collagenase expression in corneal epithelium cells Proc Natl Acad Sci USA 90 1993 8672 8682
13. NG Bazan BL Scott TS Reddy MZ Peliasz Decreased content of docosahexanoate and arachidonate in plasma phospholipids in Usher's syndrome Biochem Biophys Res Commun 141 1986 600 604
14. NG Bazan Metabolism of AA in the retina and retinal pigment epithelium: biological effects of oxygenated metabo- lites of AA LZ Bito J Stjernschantz The Ocular Effects of Prostaglandins and Other Eicosanoids 1989 Allan R. Liss Inc New York 15 37
15. NG Bazan Tile metabolism of omega-3 polyunsaturated fatty acids in the eye: the possible role of docosahexaenoic acid and docosanoids in retinal physiology and ocular pathology LZ Bito J Stjernschantz The Ocular Effects of Prostaglandins and Other Eicosanoids 1989 Allan R. Liss Inc New York 95 112
16. NG Bazan JM Cluzel Membrane-derived second messengers as targets for neuroprotection: Platelet-activating factor PJ Marangos H Lal Emerging Strategies in Neuroprotection: Advances in Neuroprotection 1992 Birkhauser Boston 238 251
17. NG Bazan VL Marcheselli G Allan An inhibitor of injury-induced COX-2 transcriptional activation elicits neuropro-tection in a brain damage model J Vane Improved non-steroidal anti-inflammatory drugs: COX-2 enzyme inhibitors 1996 William Harvey Press and Kluwer Academic Publishers Lancaster
18. JS Beckman TW Beckman implications for endothelial injury from nitric oxide and superoxide Proc Natl Acad Sci USA 87 1990 1620 1624
19. M Berkelaar DB Clarke YC Wang Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats J Neurosci 14 1994 4368 4374
20. P Bhattacherjee The role ofarachidonate metabolites in ocular inflammation LZ Bito J Stjernschantz The Ocular Effects of Prostaglandins and Other Eicosanoids 1989 Allan R. Liss Inc New York 211 227
21. DL Birkle NG Bazan Effects of potassium depolarization on the synthesis of prostaglandins and hydroxytetraenoic acids (HETE) in the rat retina Biochim Biophys Acta 795 1984 564 573
22. DL Birkle NG Bazan Lipoxygenase and cyclooxygenase reaction products and incorporation into glycerolipids of radiolabeled AA in the bovine retina Prostaglandins 27 1984 203 217
23. DL Birkle JJ Sanitato HE Kaufman NG Bazan Arachidonic metabolism to eicosanoids in herpes virus-infected rabbit cornea Invest Ophthalmol Vis Sci 27 1986 1443 1446
24. LZ Bito Prostaglandins: A new approach to glaucoma management with a new, intriguing side effect Surv Ophthalmol 41 Suppl 2 1997 S1 S14
25. LZ Bito Species differences in the response of the eye to irritation and trauma: A hypothesis of divergence in ocular defense mechanisms and the choice of experinaental animals for eye research Exp Eye Res 39 1984 807 829
26. H Bito Z Honda M Nakamura T Shimizu Cloning, expression and tissue distribution of rat platelet-activating factor receptor cDNA Eur J Biochem 221 1994 211 218
27. LZ Bito J Stjernschantz B Resul The ocular effects of prostaglandins and the therapeutic potential of a new PGF2 alpha analog, PhXA41 (latanoprost) for glaucoma management J Lipid Mediat 6 1993 535 543
28. ML Blank ZL Smith V Fitzgerald F Snyder The CoA-independent transacylase in PAF biosynthesis: tissue distribution and molecular species selectivity Biochim Biophys Acta 1254 1995 295 301
29. P Braquet L Tougui TY Shen BB Vargaftig Perspectives in platelet-activating factor research Pharmacol Rev 7 1987 135 139
30. CB Camras Mechanism of the prostaglandin-induced reduction of intraocular pressure in humans Adv Prostaglandin Thromboxane Leukot Res 23 1995 519 525
31. CB Camras LZ Bito KE Eakins Reduction ofintraocular pressure by prostaglandins applied topically to the eyes of conscious rabbits Invest Ophthalmol Vis Sci 28 1987 465 469
32. GD Clark LT Happel CF Zorumski NG Bazan Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor Neuron 9 1989 1211 1216
33. JC Clohisy TJ Connolly KD Bergman Prostanoid-induced expression of matrix metalloproteinase-I messenger ribonucleic acid in rat osteosarcoma cells Endocrinology 135 1994 1447 1454
34. JA Corbett G Kwon J Turk ML McDaniel IL-1 beta induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of Langerhans: activation of cyclooxygenase by nitric oxide Biochemistry 32 1993 13767 13770
35. S Csukas P Bhattacherjee L Rhodes CA Paterson Prostaglandin E2 and F2 alpha binding sites in the bovine iris ciliary body Invest Ophthalmol Vis Sci 34 1993 2237 2245
36. EB Dreyer ZH Pan S Storm SA Lipton Greater sensitivity of larger ganglion cells to NMDA-mediated cell death Neuroreport 5 1994 629 631
37. B El Azzouzi P Jurgens J Benveniste Y Thomas Immuno-regulatory functions of paf-acether IX. Modulation of apoptosis in an immature T cell line. Biochem Biophys Res Commun 190 1993 320 324
38. 2 L Packer Methods in Enzymology 105 1984 Academic Press San Diego 59 61
39. E Garcia-Valenzuela W Gorczyca Z Darzynkiewicz SC Sharma Apoptosis in adult retinal ganglion cells after axotomy J Neurobiol 25 1994 431 438
40. EJ Goetzl S An L Zeng Specific suppression by prostaglandin E2 of activation-induced apoptosis of human CD4+CD8+ T lymphoblasts J Immunol 154 1995 1041 1047
41. EJ Goetzl S An WL Smith Specificity of expression and effects of eicosanoid mediators in normal and human diseases FASEBJ 9 1995 1051 1058
42. N Gordon Apoptosis (programmed cell death) and other reasons for elimination of neurons and axons Brain Dev 17 1995 73 77
43. M Hattori H Arai K Inoue Purification and characterization of bovine brain platelet-activating factor acetylhydrolase J Biol Chem 268 1993 18748 18753
44. Z Honda M Nakamura I Miki Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung Nature 394 1991 342 346
45. Z Honda T Takano Y Gotoh Transfected platelet-activating factor receptor activates mitogen-activated protein (MAP) kinase and MAP kinase in Chinese hamster ovary cells J Biol Chem 269 1994 2307 2315
46. JS Hurst HE Bazan The platelet-activating factor precursor of the injured cornea is selectively implicated in arachidonate and eicosanoid release Curr Eye Res 12 1993 655 663
47. JS Hurst M Balazy HEP Bazan NG Bazan The epithelium, endothelium and stroma of the rabbit cornea generate (12S)-hydroxyeicosatetraenoic acid as the main lipoxygenase metabolite in response to injury J Biol Chem 266 1991 6726 6730
48. A Ito T Nose S Takahashi Y Mori Cyclooxygenase inhibitors augment the production of pro-matrix metalloproteinase 9 (progelatinase B) in rabbit articular chondrocytes FEBS Lett 360 1995 75 79
49. GV Jager JL van Delft NJ van Haeringen Antagonist of platelet-activating factor prevents prostaglandin E2-induced ocular hypertension in rabbits Prostaglandins 45 1992 97 105
50. MM Jumblatt CA Paterson Prostaglandin E2 effects on corneal endothelial cyclic adenosine monophosphate synthesis and cell shape are mediated by a receptor of the EP2 subtype Invest Ophthalmol Vis Sci 32 1991 360 365
51. 1 hippocampal long-term potentiation Nature 367 1994 175 179
52. DA Kujubu BS Fletcher BC Varnum TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue J Biol Chem 266 1991 12866 12872
53. DA Kujubu HR Herschman Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene J Biol Chem 267 1992 7991 7994
54. PS Kulkarni AA metabolism in human and bovine retina J Occul Pharmacol 7 1991 135 139
55. PS Kulkarni BD Srinivasan Cyclooxygenase and lipoxygenase pathways in the anterior uvea and conjunctiva LZ Bito J Stjernschautz The Ocular Effects of Prostaglandins and other Eicosaniods 1989 Alan R. Liss, Inc. New York 39 52
56. R Kumar S Harvey N Kester Production and effects of platelet-activating factor in the rat brain Biochim Biophys Acta 963 1988 375 383
57. D Kunz NP Gerard C Gerard The human leukocyte platelet-activating factor receptor, cDNA cloning, cell surface expression, and construction of a novel epitope-bearing analog J Biol Chem 267 1992 9101 9106
58. A Kuruvila C Pielop WT Shearer Platelet-activating factor induces the tyrosine phosphorylation and activation of phospholipase C-gamma 1, Fyn and Lyn kinases, and phosphatidylinositol 3-kinase in a human B cell line J Immunol 153 1994 5433 5442
59. S Lake H Gullberg J Wahlqvist Cloning of the rat and human prostaglandin F2 alpha receptors and the expression of the rat prostaglandin F2 alpha receptor FEBS Lett 355 1994 317 325
60. R Lang M Lustig E Francois Apoptosis during macrophage-dependent ocular tissue remodelling Development 120 1994 3395 3403
61. RW Lim BC Varnum HR Herschman Cloning of tetradecanoyl phorbol ester-induced ℬprimary responseℭ sequences and their expression in density-arrested Swiss 3T3 cells and a TPA non-proliferative variant Oncogene 1 1987 263 270
62. M Liminga L Hornsten HW Sprecher EH Oliw Arachidonate 15-1ipoxygenase in human corneal epithelium and 12- and 15-1ipoxygenases in bovine corneal epithelium: comparison with other bovine 12-1ipoxygenases Biochim BiophysActa 1210 1994 288 296
63. N Lin HE Bazan P Braquet NG Bazan Prolonged effect of a new platelet-activating factor antagonist on ocular vascular permeability in an endotoxin model of uveitis Curr Eye Res 10 1991 19 24
64. MD Linnik RH Zobrist MD Hatfield Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats Stroke 24 1993 2002 2008
65. Likiw WL, Gordon WC, Bazan NG: Levels of transcription factor API-, AP2-, SPI-, GAS-, NFKG- and TFIID-DNA binding during rat retinal neovascularization. (Submitted for presentation, ARVO, 1997)
66. VL Marcheselli T Panetta P Braquet Effects of platelet-activating factor antagonist (BN 52021) on cerebral lipid metabolism following ischemia reperfusion in the gerbil Ann New York Acad of Sci 559 1989 468 470
67. VL Marcheselli Inhibition by a platelet-activating factor antagonist J Biol Chem 271 1996 24794 24799
68. VL Marcheselli NG Bazan Platelet-activating factor is a messenger in the electroconvulsive shock-induced transcriptional activation of c-fos and zif-268 in hippocampus J Neurosci Res 37 1994 54 61
69. VL Marcheselli NG Bazan Platelet Activating Factor (PAF) enhances glutamic acid release in the retina through a presynaptic receptor Invest Ophthalmol Vis Sci 34 1993 1048
70. JL Masferrer PS Kulkarni Cyclooxygenase-2 inhibitors: a new approach to the therapy of ocular inflammation Surv Ophthalmol 41 Suppl 2 1997 S35 S40
71. T Matsuo MS Cynader The EP2 receptor is the predominant prostanoid receptor in the human ciliary muscle BrJ Ophthahnol 77 1993 110 114
72. PM Mertz DL DeWitt WG Stetler-Stevenson LM Wahl Interleukin 10 suppression of monocyte prostaglandin H synthase-2 Mechanisms of inhibition of prostaglandin-dependent matrix metalloproteinase production. J Biol Chem 269 1994 21322 21329
73. I Morita M Schindler MK Regier Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2 J Biol Chem 270 1995 10902 10908
74. H Mutoh H Bito M Minami Two different promoters direct expression of two distinct forms of mRNAs of human platelet-activating factor receptor FEBS Lett 322 1993 129 134
75. M Nakamura Z Honda T Matsumoto Isolation and properties of platelet-activating factor receptor cDNAs J Lipid Mediat 6 1993 163 168
76. S Nirenberg C Cepko Targeted ablation of diverse cell classes in the nervous system in vivo J Nenrosci 13 1993 3238 3251
77. T Nitatori N Sato S Waguri Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis J Neurosci 15 1995 1001 1011
78. MK O'Banion VD Winn DA Young cDNA cloning and functional activity ofa glucocorticoid-regulated inflammatory cyclooxygenase Proc Natl Acad Sci USA 89 1992 4888 4892
79. T Panetta VL Marcheselli P Braquet Effects of a platelet-activating factor antagonist (BN 52021) on free fatty acids, diacylglycerols, polyphosphoinositides and blood flow in the gerbil brain: Inhibition of ischemia-reperfusion induced cerebral injury Biochem Biophys Res Commun 149 1987 580 587
80. DS Papermaster J Windle Death at an early age Apoptosis in inherited retinal degenerations. Invest Ophthalmol Vis Sci 36 1995 977 983
81. H Pollard C Charriaut-Marlangue S Cantagrel Kainate-induced apoptotic cell death in hippocampal neurons Neuroscience 63 1994 7 18
82. C Portera-Calilliau CH Sung J Nathans R Adler Apoptotic photoreceptor cell death in mouse models of retinutis pigmentosa Proc Natl Acad Sci USA 91 1994 974 978
83. JHM Prehn J Krieglstein Platelet-activating factor antagonists reduce excitotoxic damage in cultured neurons from embryonic chick telencephalon and protect the rat hippocampus and neocortex from ischemic injury in vivo J Neurosci Res 34 1993 179 188
84. SM Prescott GA Zimmerman TM Mclntyre Platelet-activating factor J Biol Chem 265 1990 17381 17384
85. WA Pryor GL Squadriro The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide AmJ Physiol 268 1995 699 722
86. SA Qureshi CK Joseph M Rim v-Src activates both protein kinase C-dependent and independent signaling pathways in mouse fibrohlasts Oncogene 6 1991 995 996
87. JW Regan TJ Bailey DJ Pepperl Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype Mol Pharmacol 46 1994 213 220
88. JT Rosenbaum RS Boney JR Samples FH Valone Synthesis ofplatelet-activating factor by ocular tissue from inflamed eyes Arch Ophthalmol 109 1991 410413
89. R Salvatori PT Guidon Jr BE Rapuano RS Bockman Prostaglandin E 1 inhibits collagenase gene expression in rabbit synoviocytes and human fibroblasts Endocrinology 131 1992 21 28
90. RA Schumer SM Podos The nerve of glaucoma! Arch Ophthalmol 112 1994 37 44
91. CE Seyfried VL Schweickart R Godiska PW Gray The platelet-activating factor receptor gene (PTAFR) contains no introns and maps to chromosome 1 Genomics 13 1992 832 834
92. S Shahinfar MO Edward DE Tso A pathologic study of photoreceptor cell death in retinal photic injury Curr Eye Res 10 1991 47 59
93. Y Sheng DL Birkle Intracamerally injected platelet-activating factor (PAF) induces marked intraocular inflammatory reactions Curr Eye Res 11 1992 1067 1078
94. PL Smiley KE Stremler SM Prescott Oxidatively fragmented phosphatidylcholines activate human neutrophils through the receptor for platelet-activating factor J Biol Chem 266 1991 11104 11110
95. F Snyder Platelet-activating factor and its analogs metabolic pathways and related intracellular processes Biochim Biophys Acta 1254 1995 231 249
96. DM Staffarini SM Prescott GA Zimmerman TM McIntyre Platelet-activating factor acetylhydrolase activity in human tissues and blood cells Lipids 26 1991 967 975
97. T Sugimoto H Tsuchimochi CG McGregor Molecular cloning and characterization of the platelet-activating factor receptor gene expressed in the human heart Biochem Biophys Res Commun 189 1992 617 624
98. Y Tao HE Bazan NG Bazan Platelet-Activating Factor (PAF) induces the expression ofurokinase-type, but not the tissue-type, plasminogen activator in rabbit corneal epithelium (abstract) Invest Ophthahnol Vis Sci 35 Suppl 1994 1457
99. Y Tao HE Bazan NG Bazan Platelet-activating factor induces the metalloproteinases-1 and -9, but not -2 or -3, in the corneal epithelium Invest Ophthalmol Vis Sci 36 1995 345 354
100. Y Tao NG Bazan HEP Bazan Platelet-activating factor (PAF) increases prostaglandin synthase-2 (COX-2) gene expression in corneal epithelium (abstract) Invest Ophthalmol Vis Sci 36 Suppl 1995 S573
101. L Varner HEP Bazan A mitogen-activated protein kinase (MAP-k) cascade is stimulated by platelet-activating factor (PAF) in corneal epithelium (abstract) Invest Vis Sci 36 Suppl 1995 Sl41
102. JA Woodward DE Chan ME Burke Studies on the ocular hypotensive effects ofprostaglandin F2 alpha ester prodrugs and receptor selective prostaglandin analogs J Ocul Pharmacol 10 1994 177 193
103. DF Woodward JW Regan S Lake A Ocklind The Molecular Biology and Ocular Distribution of Prostanoid Receptors Surv Ophthalmol 41 Suppl 2 1997 S15 S21
104. WL Xie JG Chipman DL Robertson Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing Proc Natl Acad Sci USA 88 1991 2692 2696
105. K Yamagata KI Andreasson WE Kaufmann Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids Neuron 11 1993 371 386
106. GA Zimmerman SM Prescott TM McIntyre Oxidatively fragmented phospholipids as inflammatory mediators: the dark side of polyunsaturated lipids J Nutr 125 1995 1661S 1665S