A practical device for histological fixative procedures that limits formaldehyde deleterious effects in laboratory environments

Journal of Neuroscience Methods

Volumn 72, Issue 1, 1997, Pages 65-70

  Nogueira, M I ^a   Barbieri, C ^b   Vieira, R ^a   Marques, E R ^a   Moreno, J E H ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Fixative procedures; Formaldehyde; Formaldehyde vapors evaluation; Histological fixation; Paraformaldehyde; Transcardiac fixative perfusion

Indexed keywords

FORMALDEHYDE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVICE; HISTOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE SECTION;

AIR POLLUTANTS; ANIMALS; EQUIPMENT SAFETY; FIXATIVES; FORMALDEHYDE; LABORATORIES; MALE; PERFUSION; POLYMERS; RATS; TISSUE FIXATION; VENTILATION;

EID: 0030949852     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0270(96)00158-6     Document Type: Article

References (29)

1. ACGIH, American Conference of Governmental Industrial Hygienists, Technical Information Office (1995) Threshold Limit Values for chemical substances, physical agents and biological exposure indices. ACGIH, Cincinnati, OH, 2-50. 129p.
2. Alexandersson, R. and Hedenstierna, G. (1988) Respiratory hazards associated with exposure to formaldehyde and solvents in acid-curing paints, Arch. Environ. Health, 43: 222-227.
3. Allen, R.E., Moshinsky, M.J., Stallone, R.J. et al. (1970) Corrosive injuries of the stomach, Arch. Surg., 100: 409-413.
4. Andersen, I. and Molhave, L. (1983) Controlled human studies with formaldehyde. In Gibson, J.E. (Ed.), Formaldehyde Toxicity. Hemisphere, Washington DC, pp. 154-165.
5. Berke, J.H. (1987) Cytologic examination of the nasal mucosa in formaldehyde exposed workers, J. Occup. Med., 29: 681-684.
6. Bernstein, R.S., Stayner, L.T., Elliott, L.J., Kimbroug, R., Falk, H. and Blade, L.. (1984) Inhalation exposure to formaldehyde: an overview of its toxicology, epidemiology, monitoring and control, Am. Ind. Hyg. Assoc. J., 45: 778-785.
7. Berod, A., Hartman, B.K. and Pujol, J.F. (1981) Importance of fixation in immunohistochemistry: use of formaldehyde solutions at variable pH for the localization of tyrosine hydroxylase, J. Histochem. Cytochem., 29: 844-850.
8. Bhalla, D.K., Mahavni, V., Nguyen, T. and McClure, T. (1991) Effects of acute exposure to formaldehyde on surface morphology of nasal epithelia in rats, J. Toxicol. Environ. Health, 33: 171-188.
9. Blair, A., Stewart, P., O'Berg, M., Gaffey, W., Walrath, J., Ward, J., Bales, R., Kaplan, S., and Cubit, D. (1986). Mortality among industrial workers exposed to formaldehyde, J. Natl. Cancer Inst., 76: 1071-1084.
10. Burkhart, K.K., Kuling, K.W. and McMartin, K.E. (1990) Formate levels following a formalin ingestion, Vet. Hum. Toxicol., 32: 135-137.
11. Casteel S.W., Vernon, R.J. and Bailey, E.M. (1987) Formaldehyde: toxicology and hazards, Vet. Hum. Toxicol., 29: 31-33.
12. Eells, J.T., McMartin, K.E., Black, K., Virayotha, V., Tisdell, R.H., and Tephly, T.R. (1981) Formaldehyde poisoning. Rapid metabolism to formic acid, J. Am. Med. Assoc., 246: 1237-1258.
13. Fleischer, J.M. (1987) Medical student's exposure to formaldehyde in gross anatomy laboratories, NY State J. Med., 87: 385-388.
14. Gerfen, C.R. and Sawchenko, P.E. (1984) An anterograde neuroanatomical tracing method that shows the detailed morphology of neurons, their axons and terminals immunohistochemical localization of an axonally transported plant lectin, Phaseolus vulgaris leucoagglutinin (PHA-L), Brain Res., 290: 219-238.
15. JAMA (1989) Council Report On Scientific Affairs. Formaldehyde. J. Am. Med. Assoc., 261: 1183-1187.
16. Holmström, M. and Lund, V.J. (1991) Malignant melanomas of the nasal cavity after occupational exposure to formaldehyde, Br. J. Ind. Med. 48: 9-11.
17. Hovarth, E.P., Anderson, H., Pierce, W.E., Hanrahan, L. and Wendlick, C.I.H. (1988) Effects of formaldehyde on the mucous membranes and lungs. A study of an industrial population, J. Am. Med. Assoc., 259: 701-707.
18. Khamgaokar, M.B. and Fulare, M.B. (1991) Pulmonary effects of formaldehyde exposure: an environmental epidemiological study, Indian Chest Dis. J. Allied Sci. 33: 9-13.
19. Kilburn, K.H., Warshaw, R. and Thornton, J.C. (1987) Formaldehyde impairs memory, equilibrium and dexterity in histology technicians: effects which persist for days after exposure, Arch. Environ. Health, 42: 117-120.
20. Koppel, C., Bandish, H., Schneider, V. and Ibr, K. (1990) Suicidal ingestion of formalin with fatal complications, Intensive Care Med., 16: 212-214.
21. Loomis, T.A. (1979) Formaldehyde toxicity, Arch. Pathol. Lab. Med., 103: 321-324.
22. Matanoski, G. (1980) Epidemiologic studies of mortality in pathologists. Presented at the 49th Meeting of Interagency Collaborative Group on Environmental Carcinogenesis, Bethesda, MD, Feb. 6.
23. Mesulam, M.M. (1982) Principles of horseradish peroxidase neurohistochemistry and their applications for tracing neural pathways: axonal transport, enzyme histochemistry and light microscopic analysis. In Mesulam, M.-M. (Ed.), Tracing Neural Connections with Horseradish Peroxidase, Wiley, Winchester, pp. 1-151.
24. NIOSH, National Institute for Occupational Safety and Health (1977) Formaldehyde in air. In Centers for Disease Control, Manual of Analytical Methods, 2 Ed. Department of Health, Education and Welfare, Public Health Service, Cincinnati, OH, Vol. 1, pp.125-1-125-8.
25. NIOSH, National Institute for Occupational Safety and Health (1990) Pocket Guide to Chemical Hazards. NIOSH, Cincinnati, OH.
26. Nogueira, M.I. and Barbieri, C. (1993) A practical modular mechanical device designed for histological fixative procedures, coupled with head cooling and residue collecting systems, FESBE: Fed. Soc. Biol. Exp. Abstr. p. 348.
27. Nogueira, M.I., Almeida, A.A. and D'Haro, J.E.M. (1995) Formaldehyde vapors evaluation in histological fixative environments, FESBE: Fed. Soc. Biol. Exp. Abstr. p. 439.
28. Rieke, C.K., Bowers, D.E. and Silvy, N.J. (1981) A technique for improved fixation of the pigeon central nervous system for electron microscopy, Anat. Rec., 200: 121-125.
29. Weber, R., Budmiger, H. and Siegenthaler, W. (1988) The chronic formaldehyde exposition, a misunderstood diagnostic, Schweiz. Med. Wschr., 118: 457-461.