Dopaminergic and serotonergic properties of fluoxetine

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 21, Issue 1, 1997, Pages 169-181

  Simon, Barbara ^a   Appel, James B ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

cocaine; d lysergic acid diethylamide; dopamine; drug discrimination; fluoxetine; rats; serotonin

Indexed keywords

COCAINE; DOPAMINE RECEPTOR; FLUOXETINE; LYSERGIDE;

ANIMAL EXPERIMENT; ARTICLE; DISCRIMINATIVE STIMULUS; DOPAMINERGIC SYSTEM; DRUG DISCRIMINATION; DRUG POTENTIATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; RAT; RECEPTOR DENSITY; SEROTONINERGIC SYSTEM;

ANIMALS; BEHAVIOR, ANIMAL; DOPAMINE AGONISTS; DRUG INTERACTIONS; FLUOXETINE; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN AGONISTS;

EID: 0030949744     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(96)00167-4     Document Type: Article

References (27)

1. BARRETT, R. and APPEL, J. B. (1989) Effects of Stimulation and Blockade of Dopamine Receptor Subtypes on the Discriminative Stimulus Properties of Cocaine. Psychopharm. 99: 13-16.
2. CAINE, S. B. and KOOB, G. F. (1994) Effects of Mesolimbic Dopamine Depletion on Responding Maintained by Cocaine and Food. Special Issue: Contributions of Joseph V. Brady. J. Exp. Anal. Beh. 61: 213-221.
3. CALLAHAN, P. M and CUNNINGHAM, K. A. (1995) Analysis of the Effects of Diverse Antidepressants on the Discriminative Stimulus Effects of Cocaine. In: Problems of Drug Dependence 1994: Proceedings of the 56th Annual Scientific Meeting, L. S. Harris (Ed.), pp 383, U. S. Government Printing Office, Washington, D. C.
4. CARROLL, M. E., LAC, S. T., ASENCIO, M., and DRACH, R. (1990) Fluoxetine Reduces Intravenous Cocaine Self-Administration in Rats. Pharmacol. Biochem. & Beh. 35: 237-244.
5. CAZALA, P. (1980). Effects of Lilly 110140 (Fluoxetine) on Self-Stimulation Behavior in the Dorsal and Ventral Regions of the Lateral Hypothalamus in the Mouse. Psychopharm. 71: 133-146.
6. CUNNINGHAM, K. A. and APPEL, J. B. (1987) Neuopharmacological Reassessment of the Discriminative Stimulus Properties of d-Lysergic Acid Diethylamide (LSD). Psychopharm. 91: 67-73.
7. CUNNINGHAM, K. A. and CALLAHAN, P. M. (1991) Monoamine Reuptake Inhibitors Enhance the Discriminative State Induced by Cocaine in Rats. Psychopharm. 104: 177-180.
8. CUNNINGHAM, K. A., PARIS, J. M., and GOEDERS, N. E. (1992a) Chronic Cocaine Enhances Serotonin Autoregulation and Serotonin Uptake Binding. Synapse 11: 112-123.
9. CUNNINGHAM, K. A., PARIS, J. M., and GOEDERS, N. E. (1992b) Serotonin Neurotransmission in Cocaine Sensitization. In: The Neurobiology of Drug and Alcohol Addiction: Annals of the New York Academy of Sciences, P. W. Kalivas and H. H. Samson (Eds.), Vol. 654, pp. 117-127, New York Press, New York.
10. GLENNON, R.A., and DUKAT, M., (1995). Serotonin receptor subtypes. In: Psychopharmacology: The Fourth Generation of Progress, F. E. Bloom and D. J. Kupfer (Eds.), pp 415-429, Raven Press, New York.
11. GRIGNASCHI, G. and SAMANIN, R. (1992) Role of Serotonin and Catecholamines in Brain in the Feeding Suppressant Effect of Fluoxetine. Neuropharmacol. 31: 445-449.
12. HAMMER, R. P., MARGULIES, J. E., ALLISON, B., and BRADY, L. S. (1993) Chronic Fluoxetine Treatment Up-Regulates Dopamine Receptors in the Mesolimbic Forebrain of the Rat. Depression 1: 82-87.
13. HARAGUCHI, M., SAMSON, H. H., and TOLLIVER, G. A. (1991) Reduction in Oral Ethanol Self-Administration in the Rat by the 5-HT Uptake Blocker Fluoxetine. Pharmacol., Biochem. & Beh. 35: 259-262.
14. HOFFMEISTER, F. and WUTTKE, W. (1975) Psychotropic Drugs as Negative Reinforcers. Pharmacol. Rev. 27: 419-428.
15. JAFFE, J. H. (1985) Drug Addiction and Drug Abuse. In: The Pharmacological Basis of Therapeutics, A. G. Gilman, L. S. Goodman, T. W. Rall, and F. Murad (Eds.), pp 532-581, Macmillan Publishing Company, New York.
16. KATZ, R. J., and CARROLL, B. J. (1977) Intracranial Reward After Lilly 110140 (Fluoxetine HCl): Evidence for an Inhibitory Role for Serotonin. Psychopharm. 51: 189-193.
17. KUHN, D. M., WHITE, F. J., and APPEL, J. B. (1978) The Discriminative Stimulus Properties of LSD: Mechanisms of Action. Neuropharm. 17: 257-263.
18. LECCESE, A. P., and LYNESS, W. H. (1984) The Effects of Putative 5-Hydroxytryptamine Receptor Active Agents on d-Amphetamine Self-Administration in Controls and Rats with 5,7-Dihydroxytryptamine Median Forebrain Bundle Lesions. Brain Res. 303: 153-162.
19. LUO, S. H., and LI., E. T. S. (1991) Effects of Repeated Administration of Serotonergic Agonists on Diet Selection and Body Weight in Rats. Pharmacol. Biochem. & Beh. 38: 495-500.
20. PORRINO, L. J., RITZ, M. C., GOODMAN, N. L., SHARPE, L. G., KUHAR, M. J., and GOLDBERG, S. R. (1989) Differential Effects of the Pharmacological Manipulation of Serotonin Systems on Cocaine and Amphetamine Self-Administration in Rats. Life Sci. 45: 1529-1535.
21. RICHARDSON, N. R., and ROBERTS, D. C. S. (1991) Fluoxetine Pretreatment Reduces Breaking Points on a Progressive Ratio Schedule Reinforced by Intravenous Cocaine Self-Administration in the Rat. Life Sci. 49: 833-840.
22. STRASSMAN, R. J. (1992) Human Hallucinogen Interactions with Drugs Affecting Serotonergic Neurotransmission. Neuropsychopharm. 7: 241-243.
23. TRULSON, M. E. (1986) Dissociations Between the Effects of Hallucinogens on Behavior and Raphe Unit Activity in Behaving Cats. American Society for Pharmacology and Experimental Therapeutics Meeting: New Perspectives on the Pharmacology of Hallucinogenic Drugs. Pharmacol. Biochem. & Beh. 24: 2660.
24. WHITE, F. J., and APPEL, J. B. (1981) A Neuropharmacological Analysis of the Discriminative Stimulus Properties of Fenfluramine. Psychopharm. 73: 110-115.
25. WISE, R. A. (1990) The Role of Reward Pathways in the Development of Drug Dependence. In: Psychotropic Drugs of Abuse, D. J. K. Balfour (Ed.), pp 23-58, Pergamon Press, New York.
26. WOOLVERTON, W. L., and JOHNSON, K. M. (1992) Neurobiology of Cocaine Abuse. Trends Pharm. Sci. 13: 193-131.
27. YU, D. S., L., SMITH, F. L., SMITH, D. C., and LYNESS, W. H. (1986) Fluoxetine-Induced Attenuation of Amphetamine Self-Administration in Rats. Life Sci. 39: 1383-1388.