Treatment with recombinant human erythropoietin (rHuEpo) in a patient with paroxysmal nocturnal haemoglobinuria: Evaluation of membrane proteins CD55 and CD59 with cytofluorometric assay

British Journal of Haematology

Volumn 97, Issue 3, 1997, Pages 586-588

  Astori, Cesare ^a,b   Bonfichi, Maurizio ^a   Pagnucco, Guido ^a   Bernasconi, Paolo ^a   Lazzarino, Mario ^a   Orlandi, Ester ^a   Bernasconi, Carlo ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

DAF CD55; MIRL CD59; paroxysmal nocturnal haemoglobinuria; recombinant human erythropoietin; treatment

Indexed keywords

CD59 ANTIGEN; DECAY ACCELERATING FACTOR; MEMBRANE PROTEIN; RECOMBINANT ERYTHROPOIETIN;

ADULT; ARTICLE; BLOOD TRANSFUSION; BONE MARROW BIOPSY; CASE REPORT; CYTOFLUOROMETRY; ERYTHROCYTE MEMBRANE; FLOW CYTOMETRY; GRANULOCYTE; HEMATOPOIESIS; HUMAN; MALE; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PRIORITY JOURNAL; THROMBOCYTE COUNT;

EID: 0030949546     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.912908.x     Document Type: Article

References (5)

1. Bourantas, K. (1994) High-dose recombinant human erythropoietin and low-dose corticosteroids for treatment of anaemia in paroxysmal nocturnal haemoglobinuria. Acta Haematologica, 91, 62-65.
2. Eschbach, J.W., Egrie, J.C., Downing, M.R., Browne, J.K. & Adamson, J.W. (1987) Correction of the anemia of end-stage renal disease with recombinant human erythropoietin: results of a combined phase I and II clinical trial. New England Journal of Medicine, 316, 75-78.
3. Rosse, W.F. (1990) Phosphatidylinositol-linked proteins and paroxysmal nocturnal hemoglobinuria. Blood, 75, 1595-1601.
4. Stebler, C., Tichelli, A. & Dazzi, H. (1990) High dose recombinant erythropoietin for treatment of anemia in myelodysplastic syndromes and paroxysmal nocturnal hemoglobinuria: a pilot study. Experimental Hematology, 18, 1204-1208.
5. Terstappen, L.W.M., Nguyen, M., Huang, S., Lazarus, H.M. & Medof, M.E. (1993) Defective and normal haematopoietic stem cells in paroxysmal nocturnal haemoglobinuria. British Journal of Haematology, 84, 504-514.