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Volumn 14, Issue 3, 1997, Pages 248-257

Counterregulatory hormone responses and symptoms during hypoglycaemia induced by porcine, human regular insulin, and Lys(B28), Pro(B29) human insulin analogue (insulin lispro) in healthy male volunteers

Author keywords

counterregulation; human insulin; hypoglycaemia; hypoglycaemic symptoms; insulin analogue; insulin lispro; porcine insulin

Indexed keywords

HUMAN INSULIN; INSULIN DERIVATIVE; INSULIN LISPRO; INSULIN ZINC SUSPENSION; PIG INSULIN;

EID: 0030948438     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9136(199703)14:3<248::AID-DIA337>3.0.CO;2-0     Document Type: Article
Times cited : (13)

References (45)
  • 1
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin dependent diabetes mellitus
    • DCCT Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin dependent diabetes mellitus. N Engl J Med 1993; 329: 977-985.
    • (1993) N Engl J Med , vol.329 , pp. 977-985
  • 2
    • 0027286787 scopus 로고
    • Meta-analysis of effects of intensive blood-glucose control on late complications of type I diabetes
    • Wang PH, Lau J, Chalmers TC. Meta-analysis of effects of intensive blood-glucose control on late complications of type I diabetes. Lancet 1993; 341: 1306-1309.
    • (1993) Lancet , vol.341 , pp. 1306-1309
    • Wang, P.H.1    Lau, J.2    Chalmers, T.C.3
  • 3
    • 8244225872 scopus 로고
    • Epidemiology of severe hypoglycaemia in the Diabetes Control and Complications Trial
    • DCCT Research Group. Epidemiology of severe hypoglycaemia in the Diabetes Control and Complications Trial. Am J Med 1991; 305: 355-358.
    • (1991) Am J Med , vol.305 , pp. 355-358
  • 4
    • 0023216411 scopus 로고
    • Defective glucose counterregulation after strict glycemic control of insulin dependent diabetes mellitus
    • Amiel SA, Tamborlane WV, Simonson DC, Sherwin RS. Defective glucose counterregulation after strict glycemic control of insulin dependent diabetes mellitus. N Engl J Med 1987; 316: 1376-1383.
    • (1987) N Engl J Med , vol.316 , pp. 1376-1383
    • Amiel, S.A.1    Tamborlane, W.V.2    Simonson, D.C.3    Sherwin, R.S.4
  • 5
    • 0024269080 scopus 로고
    • Effect of intensive insulin therapy on glycemic, thresholds for counterregulatory hormone release
    • Amiel SA, Sherwin R, Simonson DC, Tamborlane WV. Effect of intensive insulin therapy on glycemic, thresholds for counterregulatory hormone release. Diabetes 1988; 37: 901-907.
    • (1988) Diabetes , vol.37 , pp. 901-907
    • Amiel, S.A.1    Sherwin, R.2    Simonson, D.C.3    Tamborlane, W.V.4
  • 6
    • 0025054445 scopus 로고
    • Unawareness of hypoglycaemia and inadequate hypoglycemic counterregulation: No causal relationship with diabetic neuropathy
    • Ryder RJ, Owens DR, Hayes TM, Chatei MA, Bloom SR. Unawareness of hypoglycaemia and inadequate hypoglycemic counterregulation: no causal relationship with diabetic neuropathy. Br Med J 1990; 301: 783-787.
    • (1990) Br Med J , vol.301 , pp. 783-787
    • Ryder, R.J.1    Owens, D.R.2    Hayes, T.M.3    Chatei, M.A.4    Bloom, S.R.5
  • 7
    • 0025036037 scopus 로고
    • Unawareness of hypoglycaemia in insulin-treated diabetic patients: Prevalence and relationship to autonomic neuropathy
    • Hepburn DA, Patrick AW, Eadington DW, Ewing DJ, Frier BM. Unawareness of hypoglycaemia in insulin-treated diabetic patients: prevalence and relationship to autonomic neuropathy. Diabetic Med 1990; 7: 711-717.
    • (1990) Diabetic Med , vol.7 , pp. 711-717
    • Hepburn, D.A.1    Patrick, A.W.2    Eadington, D.W.3    Ewing, D.J.4    Frier, B.M.5
  • 9
    • 0026035949 scopus 로고
    • Reduced neuro-endocrine and symptomatic responses to subsequent hypoglycemia after one episode of hypoglycemia reduces in nondiabetic humans
    • Heller S, Creyer PE. Reduced neuro-endocrine and symptomatic responses to subsequent hypoglycemia after one episode of hypoglycemia reduces in nondiabetic humans. Diabetes 1991; 40: 223-226.
    • (1991) Diabetes , vol.40 , pp. 223-226
    • Heller, S.1    Creyer, P.E.2
  • 10
    • 0025790540 scopus 로고
    • Counterregulatory adaptation to recurrent hypoglycemia in normal humans
    • Davis M, Shamoon H. Counterregulatory adaptation to recurrent hypoglycemia in normal humans. J Clin Endocrinol Metab 1991; 73: 995-1001.
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 995-1001
    • Davis, M.1    Shamoon, H.2
  • 11
    • 0027214075 scopus 로고
    • Induction of hypoglycemia unawareness by asymptomatic nocturnal hypoglycemia
    • Veneman ThF, Mitrakou A, Mokan M, Creyer PE, Gerich J. Induction of hypoglycemia unawareness by asymptomatic nocturnal hypoglycemia. Diabetes 1993; 42: 1233-1237.
    • (1993) Diabetes , vol.42 , pp. 1233-1237
    • Veneman, Th.F.1    Mitrakou, A.2    Mokan, M.3    Creyer, P.E.4    Gerich, J.5
  • 12
    • 0026592191 scopus 로고
    • Intermittent hypoglycemia impairs glucose counterregulation
    • Widom B, Simonson DC. Intermittent hypoglycemia impairs glucose counterregulation. Diabetes 1992; 41: 1597-1602.
    • (1992) Diabetes , vol.41 , pp. 1597-1602
    • Widom, B.1    Simonson, D.C.2
  • 13
    • 0024343804 scopus 로고
    • Response to human and porcine insulin in healthy subjects
    • Heine RJ, van der Heyden EAP, van der Veen EA. Response to human and porcine insulin in healthy subjects. Lancet 1989; ii: 946-948.
    • (1989) Lancet , vol.2 , pp. 946-948
    • Heine, R.J.1    Van Der Heyden, E.A.P.2    Van Der Veen, E.A.3
  • 14
    • 0020402560 scopus 로고
    • Differential counterregulatory responses to human insulin (recombinant DNA) and purified pork insulin
    • Schluter KJ, Petersen KG, Sontheimer J, Enzmann F, Kerp L. Differential counterregulatory responses to human insulin (recombinant DNA) and purified pork insulin. Diabetes Care 1982; 5(suppl 2): 78-81.
    • (1982) Diabetes Care , vol.5 , Issue.2 SUPPL. , pp. 78-81
    • Schluter, K.J.1    Petersen, K.G.2    Sontheimer, J.3    Enzmann, F.4    Kerp, L.5
  • 15
    • 0024553190 scopus 로고
    • Warning symptoms of hypoglycaemia during treatment with human and porcine insulin in diabetes mellitus
    • Berger W, Keller U, Honegger B, Jaeggi G. Warning symptoms of hypoglycaemia during treatment with human and porcine insulin in diabetes mellitus. Lancet 1989; i: 1041-1044.
    • (1989) Lancet , vol.1 , pp. 1041-1044
    • Berger, W.1    Keller, U.2    Honegger, B.3    Jaeggi, G.4
  • 16
    • 0025812153 scopus 로고
    • Influence of human insulin on symptoms and awareness of hypoglycaemia: A randomised double blind cross-over trial
    • Egger M, Smith GD, Teuscher AU, Teuscher A. Influence of human insulin on symptoms and awareness of hypoglycaemia: a randomised double blind cross-over trial. Br Med J 1991; 303: 622-626.
    • (1991) Br Med J , vol.303 , pp. 622-626
    • Egger, M.1    Smith, G.D.2    Teuscher, A.U.3    Teuscher, A.4
  • 17
    • 0023758511 scopus 로고
    • Hormonal counterregulatory responses to human (semisynthetic and recombinant DNA) and porcine insulin induced hypoglycaemia
    • Owens DR, Vora JP, Tronier B, Keller U, Luzio S, Turkes A. Hormonal counterregulatory responses to human (semisynthetic and recombinant DNA) and porcine insulin induced hypoglycaemia. Diabetes Res 1988; 8: 17-20.
    • (1988) Diabetes Res , vol.8 , pp. 17-20
    • Owens, D.R.1    Vora, J.P.2    Tronier, B.3    Keller, U.4    Luzio, S.5    Turkes, A.6
  • 18
    • 0025053930 scopus 로고
    • A comparative study of the hormonal responses to insulin induced hypoglycaemia using semi-synthetic and pork insulin in patients with insulin dependent diabetes mellitus
    • Clausen Sjöborn N, Lins PE, Adamson V, Theodorsson E. A comparative study of the hormonal responses to insulin induced hypoglycaemia using semi-synthetic and pork insulin in patients with insulin dependent diabetes mellitus. Diabetic Med 1990; 7: 775-779.
    • (1990) Diabetic Med , vol.7 , pp. 775-779
    • Clausen Sjöborn, N.1    Lins, P.E.2    Adamson, V.3    Theodorsson, E.4
  • 19
    • 0026612547 scopus 로고
    • Hormonal counterregulation, symptom awareness, and neurophysiological function in Type 1 diabetes during insulin induced hypoglycaemia
    • Lingenfelser T, Buettner UW, Plonz C, Steffen J, Eggstein M, Jakober B. Hormonal counterregulation, symptom awareness, and neurophysiological function in Type 1 diabetes during insulin induced hypoglycaemia. Diabetic Med 1992; 9: 528-535.
    • (1992) Diabetic Med , vol.9 , pp. 528-535
    • Lingenfelser, T.1    Buettner, U.W.2    Plonz, C.3    Steffen, J.4    Eggstein, M.5    Jakober, B.6
  • 20
    • 0025823399 scopus 로고
    • Human insulin and awareness of acute hypoglycaemia symptoms in insulin dependent diabetes
    • Patrick AW, Bodmer CW, Tieszen KL, White MC, Williams G. Human insulin and awareness of acute hypoglycaemia symptoms in insulin dependent diabetes. Lancet 1991; 338: 528-532.
    • (1991) Lancet , vol.338 , pp. 528-532
    • Patrick, A.W.1    Bodmer, C.W.2    Tieszen, K.L.3    White, M.C.4    Williams, G.5
  • 21
    • 0027043086 scopus 로고
    • Double blind clinical and laboratory study of hypoglycaemia with human and porcine insulin in diabetic patients reporting hypoglycaemia unawareness after transferring to human insulin
    • Maran A, Lomas J, Archibald H, Macdonald IA, Gale EAM, Amiel SA. Double blind clinical and laboratory study of hypoglycaemia with human and porcine insulin in diabetic patients reporting hypoglycaemia unawareness after transferring to human insulin. Br Med J 1993; 306: 167-171.
    • (1993) Br Med J , vol.306 , pp. 167-171
    • Maran, A.1    Lomas, J.2    Archibald, H.3    Macdonald, I.A.4    Gale, E.A.M.5    Amiel, S.A.6
  • 22
    • 0012943276 scopus 로고
    • Methods of investigation of insulin induced hypoglycaemia
    • Frier BM, Fisher BM, eds. London: Edward Arnold
    • Heine RJ. Methods of investigation of insulin induced hypoglycaemia. In: Frier BM, Fisher BM, eds. Hypoglycaemia and Diabetes: Clinical and Physiological Aspects. London: Edward Arnold, 1993: 165-175.
    • (1993) Hypoglycaemia and Diabetes: Clinical and Physiological Aspects , pp. 165-175
    • Heine, R.J.1
  • 23
    • 0001065636 scopus 로고
    • Biological aspects of a new insulin analog: Lys(28), Pro(B29) - Human insulin
    • Shaw W, Su KSE. Biological aspects of a new insulin analog: Lys(28), Pro(B29) - human insulin (Abstract). Diabetes 1991; 40 (Suppl 1): 464A.
    • (1991) Diabetes , vol.40 , Issue.1 SUPPL.
    • Shaw, W.1    Su, K.S.E.2
  • 24
    • 0004748594 scopus 로고
    • Subcutaneous absorption of fast acting insulin analogs: Kinetics and bioeffective ness
    • Radziuk J, Davies S, Pye S, DiMarchi R, Shields J, Chance R. Subcutaneous absorption of fast acting insulin analogs: kinetics and bioeffective ness (Abstract). Diabetologia 1992; 35 (suppl 1): A3.
    • (1992) Diabetologia , vol.35 , Issue.1 SUPPL.
    • Radziuk, J.1    Davies, S.2    Pye, S.3    DiMarchi, R.4    Shields, J.5    Chance, R.6
  • 26
    • 0027972684 scopus 로고
    • Lys(B28)Pro(B29)-human insulin a rapidly absorbed analogue of human insulin
    • Howey DC, Bowsher RR, Brunelle RL, Woodworth JR. Lys(B28)Pro(B29)-human insulin a rapidly absorbed analogue of human insulin. Diabetes 1994; 43: 396-402.
    • (1994) Diabetes , vol.43 , pp. 396-402
    • Howey, D.C.1    Bowsher, R.R.2    Brunelle, R.L.3    Woodworth, J.R.4
  • 27
    • 0019458610 scopus 로고
    • Use of the superficial hand vein as alternative site for the measurement of aminoacid concentrations and for the study of glucose and alanine kinetics
    • Albumrad N, Rabin D, Diamond M, Lacey W. Use of the superficial hand vein as alternative site for the measurement of aminoacid concentrations and for the study of glucose and alanine kinetics. Metabolism 1981; 30: 936-940.
    • (1981) Metabolism , vol.30 , pp. 936-940
    • Albumrad, N.1    Rabin, D.2    Diamond, M.3    Lacey, W.4
  • 28
    • 0026597462 scopus 로고
    • Arterial, arterialized venous and venous and capillary blood glucose measurements in normal man during hyperinsulinaemic euglycaemia and hypoglycaemia
    • Liu D, Moberg E, Kollind K, Lins P-E, Macdonald IA. Arterial, arterialized venous and venous and capillary blood glucose measurements in normal man during hyperinsulinaemic euglycaemia and hypoglycaemia. Diabetologia 1992; 35: 287-290.
    • (1992) Diabetologia , vol.35 , pp. 287-290
    • Liu, D.1    Moberg, E.2    Kollind, K.3    Lins, P.-E.4    Macdonald, I.A.5
  • 29
    • 0003190213 scopus 로고
    • Modifications in the 28-29 positions of the insulin B-chain alter binding to the IGF-1 receptor with minimal effect on insulin receptor binding
    • Slieker LJ, Sundell K. Modifications in the 28-29 positions of the insulin B-chain alter binding to the IGF-1 receptor with minimal effect on insulin receptor binding (Abstract). Diabetes 1991; 40 (suppl 1): 464A.
    • (1991) Diabetes , vol.40 , Issue.1 SUPPL.
    • Slieker, L.J.1    Sundell, K.2
  • 30
    • 0004815444 scopus 로고
    • Lys(B28)Pro(B29)-Human insulin: An equipotent analog of human insulin with rapid onset and short duration of action
    • Howey DC, Hooper SA, Bowsher RR. Lys(B28)Pro(B29)-Human insulin: an equipotent analog of human insulin with rapid onset and short duration of action (Abstract). Diabetes 1991; 40 (suppl 1): 423A.
    • (1991) Diabetes , vol.40 , Issue.1 SUPPL.
    • Howey, D.C.1    Hooper, S.A.2    Bowsher, R.R.3
  • 31
  • 32
    • 0026048413 scopus 로고
    • Symptoms of acute insulin induced hypoglycemia in humans with and without IDDM. Factor-analysis approach
    • Hepburn DA, Deary IJ, Frier BM, Patrick AW, Quinn JD, Fisher B. Symptoms of acute insulin induced hypoglycemia in humans with and without IDDM. Factor-analysis approach. Diabetes Care 1991; 14: 949-957.
    • (1991) Diabetes Care , vol.14 , pp. 949-957
    • Hepburn, D.A.1    Deary, I.J.2    Frier, B.M.3    Patrick, A.W.4    Quinn, J.D.5    Fisher, B.6
  • 33
    • 0023238706 scopus 로고
    • Hypoglycaemia unawareness in diabetics transferred from beef/porcine insulin to human insulin
    • Teuscher A, Berger WG. Hypoglycaemia unawareness in diabetics transferred from beef/porcine insulin to human insulin. Lancet 1987; ii: 382-385.
    • (1987) Lancet , vol.2 , pp. 382-385
    • Teuscher, A.1    Berger, W.G.2
  • 34
    • 0025103638 scopus 로고
    • Differential effects of human and pork insulin induced hypoglycaemia in neuronal functions in humans
    • Kern W, Lieb K, Kerner W, Born J, Fehm HL. Differential effects of human and pork insulin induced hypoglycaemia in neuronal functions in humans. Diabetes 1990; 39: 1091-1098.
    • (1990) Diabetes , vol.39 , pp. 1091-1098
    • Kern, W.1    Lieb, K.2    Kerner, W.3    Born, J.4    Fehm, H.L.5
  • 35
    • 0026749845 scopus 로고
    • Double blind crossover comparison of human and porcine insulins in patients reporting lack of hypoglycaemia awareness
    • Colagiuri S, Miller J, Petrocz P. Double blind crossover comparison of human and porcine insulins in patients reporting lack of hypoglycaemia awareness. Lancet 1992; 339: 1432-1435.
    • (1992) Lancet , vol.339 , pp. 1432-1435
    • Colagiuri, S.1    Miller, J.2    Petrocz, P.3
  • 36
    • 0027363076 scopus 로고
    • Mechanisms of awareness of hypoglycaemia: Perception of neurogenic rather than neuroglycopenic symptoms
    • Towler DA, Havlin CD, Craft S, Creyer PE. Mechanisms of awareness of hypoglycaemia: perception of neurogenic rather than neuroglycopenic symptoms. Diabetes 1993; 42: 1791-1798.
    • (1993) Diabetes , vol.42 , pp. 1791-1798
    • Towler, D.A.1    Havlin, C.D.2    Craft, S.3    Creyer, P.E.4
  • 37
    • 0023120629 scopus 로고
    • Glycemic thresholds for activation of glucose counterregulatory systems are higher than the threshold for symptoms
    • Schwartz NS, Clutter WE, Shah SD, Cryer P. Glycemic thresholds for activation of glucose counterregulatory systems are higher than the threshold for symptoms. J Clin Invest 1987; 79: 777-781.
    • (1987) J Clin Invest , vol.79 , pp. 777-781
    • Schwartz, N.S.1    Clutter, W.E.2    Shah, S.D.3    Cryer, P.4
  • 39
    • 0024354708 scopus 로고
    • Influence of duration of hypoglycemia on the hormonal counteregulatory response in normal subjects
    • Kerr D, MacDonald IA, Tattersall RB. Influence of duration of hypoglycemia on the hormonal counteregulatory response in normal subjects. J Clin Endocrinol Metab 1989; 68: 1118-1122.
    • (1989) J Clin Endocrinol Metab , vol.68 , pp. 1118-1122
    • Kerr, D.1    MacDonald, I.A.2    Tattersall, R.B.3
  • 40
    • 0025763535 scopus 로고
    • Importance of insulin in subjective, cognitive, and hormonal responses to hypoglycemia in patients with IDDM
    • Kerr D, Reza M, Smith N, Leatherdale BA. Importance of insulin in subjective, cognitive, and hormonal responses to hypoglycemia in patients with IDDM. Diabetes 1991; 40: 1057-1062.
    • (1991) Diabetes , vol.40 , pp. 1057-1062
    • Kerr, D.1    Reza, M.2    Smith, N.3    Leatherdale, B.A.4
  • 41
    • 0027409194 scopus 로고
    • The effects of different insulin levels on the hormonal and metabolic response to equivalent hypoglycemia in normal humans
    • Davis SN, Goldstein RE, Jacobs J, Price L, Wolfe R, Cherrington AD. The effects of different insulin levels on the hormonal and metabolic response to equivalent hypoglycemia in normal humans. Diabetes 1993; 42: 263-272.
    • (1993) Diabetes , vol.42 , pp. 263-272
    • Davis, S.N.1    Goldstein, R.E.2    Jacobs, J.3    Price, L.4    Wolfe, R.5    Cherrington, A.D.6
  • 43
    • 0026482532 scopus 로고
    • Effect of physiological hyperinsulinemia on counterregulatory hormone responses during hypoglycemia in humans
    • Mellman MJ, Davis MR, Shamoon H. Effect of physiological hyperinsulinemia on counterregulatory hormone responses during hypoglycemia in humans. J Clin Endocrinol Metab 1992; 75: 1293-1297.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1293-1297
    • Mellman, M.J.1    Davis, M.R.2    Shamoon, H.3
  • 44
    • 1842391254 scopus 로고
    • The absorption kinetics of subcutaneously injected insulin and two monomeric analogs
    • Radziuk J, Candas B, Davies J, Yang M, DiMarchi R, Chance R. The absorption kinetics of subcutaneously injected insulin and two monomeric analogs (Abstract). Diabetes 1991; 40 (suppl 1): A465.
    • (1991) Diabetes , vol.40 , Issue.1 SUPPL.
    • Radziuk, J.1    Candas, B.2    Davies, J.3    Yang, M.4    DiMarchi, R.5    Chance, R.6


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