Tof-SIMS analysis of polymer bound Fmoc-protected peptides

Tetrahedron Letters

Volumn 38, Issue 14, 1997, Pages 2455-2458

  Drouot, C ^a   Enjalbal, C ^a   Fulcrand, P ^a   Martinez, J ^a   Aubagnac, J L ^a   Combarieu, R ^b   De Puydt, Y ^b  

^a CNRS   (France)

^b PSL RESEARCH UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE; POLYMER;

ARTICLE; DRUG STRUCTURE; MASS SPECTROMETRY; PEPTIDE SYNTHESIS; REACTION ANALYSIS;

EID: 0030948069     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00367-5     Document Type: Article

References (12)

1. Atherton, E.; Sheppard, R.C. Solid phase peptide synthesis: A practical approach 1988, IRL Press, Oxford.
2. Sinha, N.D. Large scale oligonucleotide synthesis using the solid phase approach in protocols for oligonucleotides and analogs. Synthesis and properties 1993, S.Agrawal Eds, Hermena Press, Totowa, New Jersey, 437.
3. Fruchtel J.S., Jung G. Angew. Chem. Int. Ed. Engl. 35:1996;17-42.
4. Barber M., Bordoli R.S., Sedgwick R.S., Tyler A.N. J. Chem. Soc. Chem. Commun. 293:1981;325-327.
5. Fenn J.B., Mann M., Meng C.K., Wong S.F., Whitehouse C.M. Mass Spectrom. Rev. 9:1990;37-70.
6. Mann M., Hojrup P., Roepstorff P. Biol. Mass Spectrom. 22:1993;338-345.
7. Drouot C., Enjalbal C., Fulcrand P., Martinez J., Aubagnac J-L., Combarieu R., De Puydt Y. Rapid Commun. Mass Spectrom. 10:1996;1509-1511.
8. Benninghoven, A.; Rüdenauer, F.G.; Werner, M.W. Secondary Ion Mass Spectrometry, Basic concepts, instrumental aspects, Applications and trends 1987, John Wiley, New York.
9. Leute A., Rading D., Benninghoven A., Schroeder K., Klee D. Adv. Mat. 6:1994;775-780.
10. a) The mass spectra were recorded on a Tof-SIMS spectrometer designed by the Charles Evans and associates compagny according to a procedure already described. b) The peptide syntheses were carried out on NovaSyn KA 125 resin (Novabiochem) using standard solid-phase protocols.
11. Grandas A., Pedroso E., Figueras A., Rivera J., Giralt E. Biomed. Environm. Mass Spectrom. 15:1988;681-684.
12. Aubagnac J-L., Gilles I., Dumy P., Escale R., Vidal J-P., Girard J-P. Bull. Soc. Chem. Fran. 130:1993;467-474.