Remarkable sequence conservation of transcripts encoding amphibian and mammalian homologues of quaking, a KH domain RNA-binding protein

Gene

Volumn 188, Issue 2, 1997, Pages 199-206

  Zorn, Aaron M ^a,b   Grow, Matthew ^a   Patterson, Kristin D ^a   Ebersole, Tom A ^a,c   Chen, Qi ^a,d   Artzt, Karen ^a   Krieg, Paul A ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d GENENTECH INC   (United States)

Author keywords

GSG STAR domain; Human; Mouse; Xenopus

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; RNA BINDING PROTEIN;

AMPHIBIA; ARTICLE; COMPARATIVE STUDY; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO DEATH; GASTRULA; GENE LOCUS; GENE MUTATION; GENETIC CONSERVATION; MAMMAL; MYELIN DEFICIENCY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA METABOLISM; SEQUENCE HOMOLOGY; VERTEBRATE; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CONSERVED SEQUENCE; DNA, COMPLEMENTARY; EMBRYO, NONMAMMALIAN; GENE EXPRESSION; HUMANS; MICE; MOLECULAR SEQUENCE DATA; RNA; RNA-BINDING PROTEINS; XENOPUS; XENOPUS PROTEINS;

AMPHIBIA; MAMMALIA; VERTEBRATA;

EID: 0030947944     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(96)00795-0     Document Type: Article

References (31)

1. Altschul, S., Warren, G., Miller, W., Myers, E.W. and Lipman, D.J. (1990) Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
2. Ashley, C.T., Wilkinson, K.D., Reines, D. and Warren, S.T. (1993) FMR1 protein: conserved RNP family domains and selective RNA binding. Science 262, 563-566.
3. Bode, V.C. (1984) Ethylnitrosourea mutagenesis and the isolation of mutant alleles for specific genes located in the t region of the mouse chromosome 17. Genetics 108, 457-470.
4. De Boulle, K., Verkerk, A., Reyniers, E., Vits, L., Hendrickx, J., VanRoy, B., VanDen Bos, F., deGraaff, E., Oostra, B. and Willems, P.J. (1993) A point mutation in the FMR-1 gene associated with fragile X mental retardation. Nature Genet. 3, 31-35.
5. Ebersole, T.A., Chen, Q., Justice, M.J. and Artzt, K. (1996) The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins. Nature Genet. 12, 260-265.
6. Gibson, T.J., Thompson, J.D. and Heringa, J. (1993) The KH domain occurs in a diverse set of RNA-binding proteins that include the antiterminator NusA and is probably involved in binding to nucleic acid. FEBS Lett. 324, 361-366.
7. Habets, G.G., van der Kammen, R.A., Stam, J.C., Michiels, F. and Collard, J.G. (1995) Sequence of the human invasion-inducing TIAM1 gene, its conservation in evolution and its expression in tumor cell lines of different tissue origin. Oncogene 10, 1371-1376.
8. Hemmati-Brivanlou, A., de la Torre, J.R., Holt, C. and Harland, R.M. (1991) Cephalic expression and molecular characterization of Xenopus En-2. Development 111, 715-724.
9. Higgins, D.G., Bleasby, A.J. and Fuchs, R. (1992) CLUSTAL V: improved software for multiple sequence alignment. Comp. Appl. Biosci. 8, 189-191.
10. Jones, A.R. and Schedl, T. (1995) Mutations in gld-1, a female germ cell-specific tumor suppressor gene in C. elegans, affect a conserved domain also found in Src-associated protein Sam68. Genes Dev. 9, 1491-1504.
11. Justice, M.J. and Bode, V.C. (1988) Three ENU-induced alleles of the murine quaking locus are recessive embryonic lethal mutations. Genet. Res. 51, 95-102.
12. Krieg, P.A. and Melton, D.A. (1987) In vitro RNA sythesis with SP6 RNA polymerase. Methods Enzymol. 155, 397-415.
13. Lock, P., Fumagalli, S., Polakis, P., McCormick, F. and Courtneidge, S. (1996) The human p62 cDNA encodes Sam68 and not the RasGAP-associated p62 protein. Cell 84, 23-24.
14. Mahone, M., Saffman, E.E. and Lasko, P.L. (1995) Localizated Bicaudal-C RNA encodes a protein containing a KH domain, the RNA binding motif of FMR1. EMBO J. 14, 2043-2055.
15. Matunis, M.J., Michael, W.M. and Dreyfuss, G. (1992) Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex-K protein. Mol. Cell. Biol. 12, 164-171.
16. Melton, D.A. and Cortese, R. (1979) Transcription of cloned tRNA genes and the nuclear partitioning of a tRNA precursor. Cell 18, 1165-1172.
17. Musco, G., Stier, G., Joseph, C., Morelli, M., Nilges, M., Gibson, T. and Pastore, A. (1996) Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome. Cell 85, 237-245.
18. Oostra, B.A. and Verkerk, A.J.M.H. (1992) The fragile X syndrome: isolation of the FMR-1 gene and characterization of the fragile X mutation. Chromosoma 101, 381-387.
19. Samorajski, T., Friede, R.L. and Reiner, P.R. (1970) Hypomyelination in the quaking mouse. A model for the analysis of disturbed myelin synthesis. J. Neuropathol. Exp. Neurol. 29, 507-523.
20. Sanger, F., Nicklen, S. and Coulson, A.R. (1977) DNA sequencing with chain terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5436-5467.
21. Shaw, G. and Kamen, R. (1986) A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46, 659-667.
22. Shedlovsky, A., King, T.R. and Dove, W.F. (1988) Saturation germ line mutagenesis of the murine t region including a lethal allele of the quaking locus. Proc. Natl. Acad. Sci. USA 85, 180-184.
23. Sidman, R.L., Dickie, M.M. and Appel, S.H. (1964) Mutant mice (quaking and jimpy) with deficient myelination in the central nervous system. Science 144, 309-311.
24. Siomi, H., Matunis, M.J., Matthew, W. and Dreyfuss, G. (1993) The pre-mRNA binding K protein contains a novel evolutionary conserved motif. Nucleic Acids Res. 21, 1193-1198.
25. Siomi, H., Choi, M., Siomi, M.C., Nussbaum, R.L. and Dreyfuss, G. (1994) Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome. Cell 77, 33-39.
26. Siomi, M.C., Siomi, H., Sauer, W.H., Srinivasan, S., Nussbaum, R.L. and Dreyfuss, G. (1995) FXR1, an autosomal homolog of the fragile X mental retardation gene. EMBO J. 14, 2401-2408.
27. Swanson, M.S. and Dreyfuss, G. (1988) Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by RNA-binding specificities. Mol. Cell. Biol. 8, 2237-2241.
28. Tonissen, K.D. and Krieg, P.A. (1994) Analysis of a variant Max sequence expressed in Xenopus laevis. Oncogene 9, 33-38.
29. Tonissen, K.F., Drysdale, T.A., Lints, T.J., Harvey, R.P. and Krieg, P.A. (1994) XNkx-2.5, a Xenopus gene related to Nkx-2.5 and tinman: evidence for a conserved role in cardiac development. Dev. Biol. 162, 325-382.
30. Wilson, T. and Treisman, R. (1988) Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences. Nature 336, 396-399.
31. Wong, G., Muller, O., Clark, R., Conroy, L., Moran, M.F., Polakis, P. and McCormick, F. (1992) Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62. Cell 69, 551-558.