Effect of mimosine on DNA synthesis in mammalian cells

Cancer Research

Volumn 57, Issue 11, 1997, Pages 2252-2255

  Tsvetkov, Lyuben M ^a   Russev, George C ^a   Anachkova, Boyka B ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY   (Bulgaria)

Author keywords

[No Author keywords available]

Indexed keywords

APHIDICOLIN; HYDROXYUREA; MIMOSINE; TRIOXYSALEN;

ANIMAL CELL; ARTICLE; DNA CROSS LINKING; DNA REPLICATION; DNA SYNTHESIS; DNA SYNTHESIS INHIBITION; ERYTHROLEUKEMIA CELL; GAMMA IRRADIATION; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; REPLICON; X IRRADIATION;

ANIMALS; APHIDICOLIN; DNA; DNA REPLICATION; ENZYME INHIBITORS; HYDROXYUREA; MICE; MIMOSINE; NUCLEIC ACID SYNTHESIS INHIBITORS; REPLICON; TRIOXSALEN; TUMOR CELLS, CULTURED; X-RAYS;

EID: 0030947670     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Lalande, M. A. Reversible arrest point in the late G1 phase of the mammalian cell cycle. Exp. Cell Res., 186: 332-339, 1990.
2. WAFI/CIPI/SDI1 is elevated through a p53-independent pathway by mimosine. Cell Growth & Differ., 7: 893-901, 1996.
3. Hughes, T. A., and Cook, P. R. Mimosine arrests the cell cycle after cells enter S-phase. Exp. Cell Res., 222: 275-280, 1996.
4. Mosca, P. J., Dijkwel, P. A., and Hamlin, J. L. The plant amino acid, mimosine, inhibits initiation at a defined origin of replication in Chinese hamster cells. Mol. Cell. Biol., 12: 4375-4383, 1992.
5. Hamlin, J. L., Mosca, P. J., Dijkwel, P. A., and Lin, H. B. Initiation of replication at a mammalian chromosomal origin. Cold Spring Harbor Symp. Quant. Biol., 58: 467-474, 1993.
6. Levenson, V., and Hamlin, J. L. A general protocol for evaluating the specific effects of DNA replication inhibitors. Nucleic Acids Res., 21: 3997-4004, 1993.
7. Gilbert, D. N., Neilson, A., Miyazava, H., DePamphilis, M. L., and Burhans, W. C. Mimosine arrests DNA synthesis at replication forks by inhibiting deoxyribonucleotide metabolism. J. Biol. Chem., 270: 9597-9606, 1995.
8. Wang, Y., Zhao, J., Clapper, J., Martin, L. D., Du, C., DeVore, E. R., Harkins, K., Dobbs, D. L., and Benbow, R. N. Mimosine differentially inhibits DNA replication and cell cycle progression in somatic cells compared to embryonic cells of Xenopus laevis. Exp. Cell Res., 217: 84-91, 1995.
9. Moska, P. J., Lin, H. B., and Hamlin, J. L. Mimosine, a novel inhibitor of DNA replication, binds to 50 kDa protein in Chinese hamster cells. Nucleic Acids Res., 23: 261-268, 1995.
10. Lin, H. B., Falchetto, R., Mosca, P. J., Shabanowitz, J., Hunt, D. F., and Hamlin, J. L. Mimosine targets serine hydroxymethyltransferase. J. Biol. Chem., 271: 2548-2556, 1996.
11. Russev, G., and Vassilev, L. Isolation of DNA fraction from Ehrlich ascites tumour cells containing the putative origin of replication. J. Mol. Biol., 161: 77-87, 1982.
12. McMaster, C. K., and Carmichael, G. Analysis of single and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. Proc. Natl. Acad. Sci. USA, 74: 4835-4838, 1977.
13. Huberman, J. H., and Riggs, A. D. On mechanism of DNA replication in mammalian chromosomes. J. Mol. Biol., 32: 327-337, 1968.
14. Painter, R. Inhibition of mammalian cell DNA synthesis by ionizing radiation. Int. J. Radiat. Biol., 49: 771-781, 1986.
15. Kaye, J., Smith, C. A., and Hanawalt, P. C. DNA repair in human cells containing photoadducts of 8-methoxypsoralen or angelicin. Cancer Res., 40: 696-702, 1980.
16. Anachkova, B., Todorova, M., Vassilev, L., and Russev, G. Isolation of short interspersed repetitive DNA sequences present in the regions of initiation of mammalian DNA replication. Eur. J. Biochem., 141: 105-108, 1984.
17. Skoog, L., and Nordenskjold, B. Effects of hydroxyurea and 1-β-D-arabinofuranosyl-cytosine on deoxyribonucleotide pools in mouse embryo cells. Eur. J. Biochem., 19: 81-89, 1971.
18. Wang, T. S-F. Eukaryotic DNA polymerases. Annu. Rev. Biochem., 60. 513-552, 1991.
19. Walters, R. A., and Hildbrand, C. E. Evidence that X-irradiation inhibits DNA replicon initiation in Chinese hamster cells. Biochem. Biophys. Res. Commun., 65: 265-271, 1975.
20. Lallev, A., Anachkova, B., and Russev, G. Effect of ionizing radiation and topoisomerase II inhibitors on DNA synthesis in mammalian cells. Eur. J. Biochem., 216: 177-181, 1993.
21. Dai, Y., Gold, B., Vishwanatha, J. K., and Rhode, S. Mimosine inhibits viral DNA synthesis through ribonucleotide reductase. Virology, 205: 210-216, 1994.
22. Tsai, W. C., and Ling, K. H. Toxic action of mimosine. J. Formosan Med. Assoc., 71: 23-30, 1972.
23. Hashiguchi, H., and Takahashi, H. Inhibition of two copper-containing enzymes, tyrosinase and dopamine β-hydroxylase, by L-mimosine. Mol. Pharmacol., 13: 362-367, 1977.
24. 1-S transition of the cell cycle by inhibitors of deoxyhypusine hydroxylation. Biochim. Biophys. Acta, 1221: 115-124, 1994.
25. Feldman, S. T., and Schonthal, A. Negative regulation of histone-H1 kinase expression by mimosine, a plant amino acid. Cancer Res., 54: 494-498, 1994.
26. Vogt, G. In vivo decondensation of chromatin and nucleolar fibrillar component by Leucaena-Leucocephala ingredient. Biol. Cell, 72: 211-215, 1991.
27. Vogt, G., Bohm, R., and Segner, H. Mimosine, a naturally occurring drug interfering primarily with the cell nucleus. J. Submicrosc. Cytol. Pathol., 25: 247-256, 1993.
28. Benbow, R. M., Zhao, J., and Larson, D. D. On the nature of origins of DNA replication in eukaryotes. Bioessays, 14: 661-670, 1992.