Postsynaptic calcineurin activity downregulates synaptic transmission by weakening intracellular Ca2+ signaling mechanisms in hippocampal CA1 neurons

Journal of Neuroscience

Volumn 17, Issue 12, 1997, Pages 4600-4611

  Wang, Jin Hui ^a   Kelly, Paul T ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Calcineurin inhibitor; Calcium calmodulin; IP3 ryanodine receptors; Positive feedback; Postsynaptic manipulation; Synaptic potentiation

Indexed keywords

CALCINEURIN; CALCIUM ION; CALMODULIN BINDING PROTEIN; DANTROLENE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; HEPARIN; PROTEIN KINASE; TACROLIMUS;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN SLICE; CALCIUM TRANSPORT; ENZYME ACTIVITY; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; VOLTAGE CLAMP;

EID: 0030947466     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-12-04600.1997     Document Type: Article

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