Polymorphism of the human immunoglobulin heavy chain locus in Rheumatoid arthritis

Autoimmunity

Volumn 25, Issue 2, 1997, Pages 109-116

  Fakhfakh, Faiza ^a,b   Ayadi, Hammadi ^b   Maalej, Abdelatif ^b   Bahloul, Zouhir ^c   Jarraya, Abdelhamid ^c   Zouali, Moncef ^d  

^a UNIVERSITY OF SFAX   (Tunisia)

^b Lab d'Immunol et de Biol Molec   (Tunisia)

^c HEDI CHAKER HOSPITAL   (Tunisia)

^d INSTITUT PASTEUR   (France)

Author keywords

Immunoglobulin genes; Polymorphisms; RFLP; Rheumatoid arthritis

Indexed keywords

AUTOANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN;

ARTICLE; DNA POLYMORPHISM; EUROPE; GENE LOCUS; GENETIC LINKAGE; HUMAN; IMMUNOGLOBULIN GENE; IMMUNOPATHOGENESIS; MULTIGENE FAMILY; RHEUMATOID ARTHRITIS; TUNISIA;

EID: 0030946480     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939708996277     Document Type: Article

References (33)

1. Panuch, R. S., Bianco, N. E., and Schur, P. H. Serum and synovial fluid IgG, IgA and IgM antigammaglobulins in rheumatoid arthritis. Arthritis Rheum. 1971; 14: 737-747.
2. Panuch, R. S., Bittner, A. K., Sullivan, M., Katz, P., and Long, S. IgM rheumatoid factor elaboration by blood, bone marrow and synovial mononuclear cells in patients with rheumatoid arthritis. Clin. Immunol. Immunopathol. 1985; 34: 387-391.
3. Kunkel, H. G., Mannik, M., and Williams, R. G. Individual antigenic specificity of isolated antibodies. Science. 1963; 140: 1218-1219.
4. Seligman, M. and Brouet, J. C. Antibody activity of human myeloma globulins. Semin. Hematol. 1973; 10: 163-177.
5. Chen, P. P., Albrandt, K., Orida, N. K., Radoux, V., Chen, E. Y., Schrantz, R., Liu, F. T., and Carson, D. A. Genetic basis of the cross-reactive idiotype on the light chain of human IgM anti-IgG autoantibodies. Proc. Natl. Acad. Sci. USA. 1986; 83: 8318-8322.
6. Siminovitch, K. A., Misener, V., Kwong, P. C., Song, Q. L, and Chen, P. P. A natural autoantibody is encoded by germline heavy and lambda light chain variable region genes without somatic mutation. J. Clin. Invest. 1989; 84: 1675-1678.
7. Pascual, V., Randen, I., Thompson, K., Sioud, M., Forre, O., Natvig, J., and Capra, J. The complete nucleotide sequence of the heavy chain variable region of six monospecific rheumatoid factors derived from Epstein-Barr virus transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. J. Clin. Invest. 1990; 86: 1320-1328.
8. Randen, I., Brown, D., Thompson, K. M., Hughes-Jones, N., Pscual, V., Victor, K., Capra, J. D., Forre, O., and Natvig, J. B. Clonally related IgM rheumatoid factors undergo affinity maturation in the rheumatoid synovial tissue. J. Immunol. 1992; 148: 3296-3301.
9. Hillert, J. Immunoglobulin gamma costant gene region polymorphisms in multiple sclerosis. J. Neuroimmunol. 1993; 43: 9-14.
10. Yang, P. M., Olsen, N. J., Siminovitch, K. A., Olee, T., Kozin, F., Carson, D. A., and Chen, P. P. Possible deletion of a developmentally regulated heavy-chain variable region gene in autoimmune diseases. Proc. Natl. Acad. Sci. USA. 1990; 87: 7907-7911.
11. Arnett, F. C., Edworthy, S. M., Bloch, D. A. McShane, D. J., Fries, J. F., Cooper, N. S, Healey, L. A., Kaplan, S. R., Liang, M. H., Luthra, H. S., Medsger, T. A., Mitchell, J. D. M., Neustadt, D. H., Pinals, R. S., Schaller, J. G., Sharp, J. T., Wilder, R. L., and Hunder, G. G. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988; 31: 315-324.
12. Berman, J. E., Mellis, S. L., Pollock, R., Smith, C., Such, H. Y., Heinke, B., Kowal, U., Chess, L., Cantor, C., and F. and Alt. Content and organisation of the human Ig VH locus: definition of three new VH families and linkage of the IgCH locus. EMBO. J. 1988; 7: 727-738.
13. Feinberg, A. P., and Volgelstein, B. A technique for radiolabelling DNA restriction fragments to high specific activity. Anal. Biochem. 1983; 132: 6-13.
14. Maniatis, T., Fritsch, E. F., and Sambrook, J., 1982. Molecular cloning: A laboratory Manual. Cold Spring Harbor, NY.
15. Southern E. M. Detection of specific sequences among DNA fragments separeted by gel electrophoresis. J. Mol. Biol. 1975; 98: 503-517.
16. Zouali, M., Madaio, M., Canoso, R., and Stollar, B. D., Restriction fragment length polymorphism analysis of the VK locus in human lupus. Eur. J. Immunol. 1989; 19: 1757-1760.
17. Matsuda, F., Shin, E. K., Nagaoka, H., Matsumura, R., Haino, M., Fukita, Y., Taka-ishi, S., Imai, T., Riley, J. H., Anand, R., Soeda, E., and Honjo, T. Structure and physical map of 64 variable segments in the 3′ 0.8-megabase region of the human immunoglobulin heavychain locus. Nature Genet. 1993; 3: 88-94.
18. Cook, G. P., Tomlinson, I. M., Walter, G., Riethman, H., Carter, N. P., Bulawela, L., Winter, G., and Rabbitts, T. H. A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q. Nature Genet. 1994; 7: 162-168.
19. Zouali, M., Chastagner, P., Abadie, A., and Theze, J. Organisation of the immunoglobulin heavy chain variable region gene complex in human lupus. Immunogenetics. 1990; 32: 451-455.
20. Shen, A., Humphries, C., Tucker, P., and Blattner, F. Human heavy chain variable region gene family non randomly rearranged in family chronic lymphatic leukemia. Proc. Natl. Acad. Sci. USA. 1987; 84: 8563-8567.
21. Sanz, I., Kelly, P., Williams, C., Scholl, S., Tucker, P., and Capra, D. The smaller human VH gene families display remarkably little polymorphism EMBO. J. 1989: 8: 3741-3748.
22. Lee, K. H., Matsuda, F., Kinashi, T., Kodaira, M., and Honjo, T. A novel family of variable region genes of the human immunoglobulin heavy chain. J. Mol. Biol. 1987; 195: 761-768.
23. Turnbull, I. F., Bernard, O., Srippakash, K. S., and Mathews, J. D. Human immunoglobulin variable region genes: a new VH sequence used to detect polymorphism. Immunogenetics. 1987; 25: 184-192.
24. Sanz, I., and Capra, J. D. The genetic origin of human autoantibodies. J. Immunol. 1988; 140: 3283-3285.
25. Van Dijk, k. W., Schroeder, H. W., P. Jr. R. M., and Milner, E. C. B. Heterogeneity in the human immunoglobulin VH locus. J. Immunol. 1989; 142: 2547-2554.
26. Souroujon, M. C. Rubeinstein, D. B., Schwartz, R. S., and Barett, K. J. Polymorphism in human H chain V region genes from the VHIII gene family. J. Immunol. 1989; 143: 706-711.
27. Zouali, M. Unravelling antibody genes. Nature Genet. 1994; 7: 118-120.
28. Fakhfakh, F., Rouis, S., Makni, H., and Ayadi, H., Détermination de la fréquence de l'allèle A2M (2) des immunoglobulines A dans la population tunisienne par la technique de RFLP. Rev. Fr. Transfus. Hémobiol. 1991; 34: 441-447.
29. Chastagner, P., Theze, J., and Zouali, M. Monomorphic organisation of human diversity (DH) heavy chain variable genes. Eur. J. Immunogenetics. 1992; 19: 303-310.
30. Zong, S. K., Nakai, S., Matsuda, F., Lee, K. H., and Honjo, T. Human immunoglobulin D segments: Isolation of a new D segment and polymorphic deletion of the D1 segment. Immunol. Letters. 1988; 17: 329-334.
31. Silvestris, F., Searles, R. A., Capra, J. D., and Williams, R. C. Studies of Anti-F (ab′) 2 antibodies and VH region distribution among SLE kindreds. J. Autoimmunity. 1989; 2: 395-401.
32. Meindl A., Kellner, H., Schattenkirchner, M., and Zachau, H. G. Polymorphism in the VK gene patterns of rheumatoid arthritis patients and control individuals. Exp. Clin. Immunogenetics. 1990; 7: 20-24.
33. McDermott, M., Kastner, D., Holloman, J. D., ScmidtWolf, G., Lundberg, A. S., Sinha, A., Hsu, C., Cashin, P., Molloy, M. G., Mulcahy, B., O'gara, F., McConnell, M., Adams, C., Khan, M. A., Wolfe, F., Rubin, L. A., Clegg, D. O., Husebye, D., Amos, C. I., Ward, R. H., and McDevitt, H. O. The role of T cell receptor beta chain genes in susceptibility to rheumatoid arthritis. Arthritis. Rheum. 1995; 38: 91-95.