Identification of an autoantibody against alpha-enolase in primary biliary cirrhosis

Journal of Hepatology

Volumn 26, Issue 4, 1997, Pages 845-851

  Akisawa, Naoaki ^a   Maeda, Takashi ^a   Iwasaki, Shinji ^a   Onishi, Saburo ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

anti alpha enolase antibody; mortality; primary biliary cirrhosis

Indexed keywords

AUTOANTIBODY; ENOLASE; PYRUVATE DEHYDROGENASE;

ACUTE HEPATITIS; ARTICLE; AUTOIMMUNITY; BILIARY CIRRHOSIS; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL ELECTROPHORESIS; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; MORTALITY; PRIORITY JOURNAL; VIRUS HEPATITIS;

EID: 0030946426     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(97)80251-6     Document Type: Article

References (28)

1. Gershwin ME, Coppel RL, Mackay IR. Primary biliary cirrhosis and mitochondrial autoantigens. Insights from molecular biology. Hepatology. 8:1988;147-151.
2. Fussey SPM, Guest JR, James OFW, Bassendine MF, Yeaman SJ. Identification and analysis of the major M2 autoantigens in PBC. Proc Natl Acad Sci USA. 85:1988;8654-8658.
3. Coppel RL, McNeilage J, Surh CD, Van de Water J, Spithill TW, Whittingham S, Gershwin ME. Primary structure of the human M2 mitochondrial autoantigen of PBC: dihydrolipoamide acetyltransferase. Proc Natl Acad Sci USA. 85:1988;7317-7321.
4. Van de Water J, Turchany J, Leung PSC, Lake J, Munoz S, Surh CD, Coppel R, Ansari A, Nakamura Y, Gershwin ME. Molecular mimicry in primary biliary cirrhosis: evidence for biliary epithelial expression of a molecule cross-reactive with pyruvate dehydrogenase complex-E2. J Clin Invest. 91:1993;2653-2664.
5. Tsuneyama K, Van de Water J, Leung PSC, Cha S, Nakanuma Y, Kaplan M, Lellis RD, Coppel R, Ansari A, Gershwin ME. Abnormal expression of the E2 component of the pyruvate dehydrogenase complex on the luminal surface of biliary epithelium occurs before major histocompatibility complex class II and BB1/B7 expression. Hepatology. 21:1995;1031-1037.
6. Manns MP, Kruger M. Immunogenetics of chronic liver diseases. Gastroenterology. 106:1994;1676-1697.
7. Maeda T, Onishi S, Saibara T, Iwasaki S, Yamamoto Y. HLA-DRw8 and primary biliary cirrhosis. Gastroenterology. 103:1992;1118-1119.
8. Onishi S, Skamaki T, Maeda T, Iwamura S, Tomita A, Saibara T, Yamamoto Y. DNA typing of HLA class II genes ; DRB10803 increases the susceptibility to primary biliary cirrhosis in Japanese. J Hepatol. 21:1994;1053-1060.
9. Chicz RM, Urban UG, Gorga JC, Vignali DAA, Lane WS, Strominger JL. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J Exp Med. 178:1993;27-47.
10. Fukuda Y, Miyazawa Y, Imoto M, Koyama Y, Nakano I, Nagura H, Kato K. In situ distribution of enolase isozymes in chronic liver disease. Am J Gastroenterol. 84:1989;601-605.
11. Moodie FDL, Leaker B, Cambridge G, Totty NF, Segal AW. Alpha-enolase: a novel cytosolic autoantigen in ANCA positive vasculitis. Kidney Int. 43:1993;675-681.
12. James SP, Hoofnagel JH, Strober W, Jones EA. Primary biliary cirrhosis: a model of autoimmune disease. Ann Intern Med. 99:1983;500-512.
13. Kaplan MM. Primary biliary cirrhosis. Adv Intern Med. 32:1987;359-377.
14. Johnson PJ, McFarlane IG. Meeting report: international autoimmune hepatitis group. Hepatology. 18:1993;998-1005.
15. Rider C, Taylor CB. Enolase isoenzymes in rat tissues: electrophoreic, chromatographic, immunological and kinetic properties. Biochim Biophys Acta. 365:1974;285-300.
16. McAllese SM, Thomson FE, Dunbar B, Fothergill JE. Human α-enolase and γ-enolase: purification and amino acid sequence comparisons. Biochem Soc Trans. 15:1987;377-378.
17. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
18. Maeda T, Loveland BE, Rowley MJ, Mackay IR. Autoantibody against dihydrolipoamide dehydrogenase, the E3 subunit of the 2-oxoacid dehydrogenase complexes: significance for primary biliary cirrhosis. Hepatology. 14:1991;994-999.
19. Engvall E. Enzyme immunoassay ELISA and EMIT. Method Enzymol. 70:1980;419-439.
20. Kato K, Ishiguro Y, Ariyoshi Y. Enolase isozymes as disease markers: distribution of three enolase subunits(α, β and γ) in various human tissues. Dis Markers. 1:1983;213-220.
21. Goldschmeding R, Van der Schoot CE, Ten Bokkel Huinink D, Hack E, Van den Ende ME, Kallenberg CGM, Von dem Borne AEGKR. Wegener's granulomatosis autoantibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils. J Clin Invest. 84:1989;1577-1587.
22. Niles JL, McCluskey T, Ahmad MF, Arnauot MA. Wegener's granulomatosis autoantigen is a novel neutrophil serine protease. (abstract) Blood. 74:1989;1888.
23. Ludemann J, Utecht B, Gross WL. Antineutrophil cytoplasmic antibodies in Wegener's granulomatosis recognize in elastinolytic enzyme. J Exp Med. 171:1990;357-362.
24. Falk RJ, Jennette JC. Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med. 318:1988;1651-1657.
25. Cohen Tervaert JW, Goldschmeding R, Elema JD, Limburg PC, Van der Giessen M, Hitema MG, Koolen MI, Hene RJ, The TH, Van der Hem GK, Von dem Borne AEGKR, Kallenberg CGM. Association of autoantibodies to myeloperoxidase with different forms of vasculitis. Arthritis Rheum. 33:1990;1264-1272.
26. Kallenberg CGM, Mulder AHL, Tervaert JWC. Antineutrophil cytoplasmic antibodies: a still-growing class of autoantibodies in inflammatory disorders. Am J Med. 93:1992;675-682.
27. Claise C, Johanet C, Bouhnik Y, Kapel N, Homberg J-C, Poupon R. Antineutrophil cytoplasmic autoantibodies in autoimmune liver and inflammatory bowel diseases. Liver. 16:1996;28-34.
28. Miles LA, Dahlberg CM, Plescia J, Felez J, Kato K, Plow EF. Role for cell surface lysines in plasminogen binding to cells: identification of α-enolase as a candidate plasminogen recepter. Biochemistry. 30:1991;1682-1691.