Effect of continuous complement inhibition using soluble complement receptor type 1 on survival of pig-to-primate cardiac xenografts

Transplantation

Volumn 63, Issue 6, 1997, Pages 900-902

  Pruitt, Scott K ^a   Bollinger, R Randal ^a   Collins, Bradley H ^a   Marsh Jr , Henry C ^b   Levin, James L ^b   Rudolph, Alfred R ^b   Baldwin III, William M ^c   Sanfilippo, Fred ^c  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b T Cell Sciences Inc   (United States)

^c JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT RECEPTOR; COMPLEMENT RECEPTOR A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPLEMENT INHIBITION; CONTROLLED STUDY; GRAFT REJECTION; HEART GRAFT; MONKEY; NONHUMAN; PRIMATE; PRIORITY JOURNAL; RECEPTOR BINDING; SURVIVAL TIME; SWINE; TISSUE NECROSIS; XENOGRAFT;

ANIMALS; COMPLEMENT INACTIVATOR PROTEINS; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNOSUPPRESSION; INFUSIONS, INTRAVENOUS; MACACA FASCICULARIS; MYOCARDIAL REPERFUSION; RECEPTORS, COMPLEMENT; SWINE; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS;

EID: 0030946331     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199703270-00017     Document Type: Article

References (9)

1. Pruitt SK, Baldwin WM III, Marsh HC Jr, Lin SS, Yeh CG, Bollinger RR. The effect of soluble complement receptor type 1 on hyperacute xenograft rejection. Transplantation 1991; 52: 868.
2. Pruitt SK, Kirk AD, Bollinger RR, et al. The effect of soluble complement receptor type 1 on hyperacute rejection of porcine xenografts. Transplantation 1994; 57: 363.
3. Weisman HF, Bartow T, Leppo MK, et al. Soluble human complement receptor type 1: in vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis. Science 1990; 249: 146.
4. Hachfeld del Balzo U, Levi R, Polley MJ. Cardiac dysfunction caused by purified human C3a anaphylatoxin. Proc Natl Acad Sci USA 1985; 82: 886.
5. Bjork J, Hugli TE, Smedegard G. Microvascular effects of anaphylatoxins C3a and C5a. J Immunol 1985; 134: 1115.
6. Pruitt SK, Baldwin WM, Sanfilippo F. The role of C3a and C5a in hyperacute rejection (HAR) of guinea pig-to-rat cardiac xenografts (Xgs). Transplant Proc 1996; 28: 600.
7. Leventhal JR, Dalmasso AP, Cromwell JW, et al. Prolongation of cardiac xenograft survival by depletion of complement. Transplantation 1993; 55: 857.
8. Leventhal JR, Sakiyalak P, Witson J, et al. The synergistic effect of combined antibody and complement depletion on discordant cardiac xenograft survival in nonhuman primates. Transplantation 1994; 57: 974.
9. Koahl J, Bitter-Suermann D. Anaphylatoxins. In: Whaley K, Loos M, Weiler JM, eds. Complement in health and disease. Dordrecht: Kluwer Academic Publishers, 1990.