Benzodiazepine mediated antagonism of opioid analgesia

Pain

Volumn 71, Issue 1, 1997, Pages 25-29

  Gear, Robert W ^a   Miaskowski, Christine ^a   Heller, Philip H ^b   Paul, Steven M ^a,c   Gordon, Newton C ^a   Levine, Jon D ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KAISER FOUNDATION HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Analgesia; Benzodiazepines; Flumazenil; GABA; Morphine; Opioids; Postoperative pain

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; FLUMAZENIL; HYDROCODONE; HYDROCODONE BITARTRATE PLUS PARACETAMOL; IBUPROFEN; MORPHINE SULFATE; OPIATE; PARACETAMOL; PLACEBO; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG ANTAGONISM; DRUG MECHANISM; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; NAUSEA; ORAL DRUG ADMINISTRATION; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PREMEDICATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEDATION; TOOTH DISEASE; TOOTH PAIN; TRANQUILIZING ACTIVITY;

ADULT; ANALGESICS, NON-NARCOTIC; ANALGESICS, OPIOID; ANTI-ANXIETY AGENTS; DIAZEPAM; DOUBLE-BLIND METHOD; DRUG SYNERGISM; FEMALE; FLUMAZENIL; GABA MODULATORS; HUMANS; IBUPROFEN; INJECTIONS, INTRAVENOUS; MALE; MOLAR, THIRD; MORPHINE; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PREMEDICATION; RECEPTORS, GABA-A; TOOTH EXTRACTION;

EID: 0030946168     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(97)03332-0     Document Type: Article

References (21)

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