1,2,3-thiadiazole: A novel heterocyclic heme ligand for the design of cytochrome P450 inhibitors

Biochemistry

Volumn 36, Issue 23, 1997, Pages 7209-7216

  Babu, Boga Ramesh ^a,b   Vaz, Alfin D N ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 PHENYLETHANOL; ACETOPHENONE; ANTIFUNGAL AGENT; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; HEME; LIGAND; OXIDOREDUCTASE; THIADIAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG DESIGN; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME INACTIVATION; ENZYME MECHANISM; LIVER MICROSOME; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RABBIT;

ACETOPHENONES; ANIMALS; BENZYL ALCOHOLS; CIRCULAR DICHROISM; CYTOCHROME P-450 ENZYME SYSTEM; DRUG DESIGN; ENZYME INHIBITORS; HEME; KINETICS; LIGANDS; MALE; MICROSOMES, LIVER; MODELS, CHEMICAL; OXIDATION-REDUCTION; PHOTOSENSITIZING AGENTS; RABBITS; THIADIAZOLES;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0030945736     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9623183     Document Type: Article

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