Structure-hydrolyzability relationships in a series of piperidinyl and tropinyl esters with antimuscarinic activity

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 3, 1997, Pages 476-481

  Xu, Rong ^a   Go, Mei Lin ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

eletronic parameter; ester hydrolysis; hydrophobicity; molecular volume; QSAR parameter; structure hydrolyzability relationship

Indexed keywords

1 METHYL 4 PIPERIDYL BENZILATE; ATROPINE; DIMETHYL SULFOXIDE; DIPHENYLACETIC ACID; HYDRATROPIC ACID DERIVATIVE; MUSCARINIC RECEPTOR BLOCKING AGENT; PHENYLACETIC ACID DERIVATIVE; PIPERIDINE DERIVATIVE; TROPANE DERIVATIVE;

ARTICLE; DRUG DESIGN; DRUG HYDROLYSIS; DRUG POTENCY; DRUG STABILITY; DRUG SYNTHESIS; HYDROPHOBICITY; MOLECULAR SIZE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEREOSPECIFICITY;

EID: 0030945532     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.476     Document Type: Article

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