Differential pathogenesis of lethal mousepox in congenic DBA/2 mice implicates natural killer cell receptor NKR-P1 in necrotizing hepatitis and the fifth component of complement in recruitment of circulating leukocytes to spleen

American Journal of Pathology

Volumn 150, Issue 4, 1997, Pages 1407-1420

  Brownstein, David G ^a   Gras, Lisa ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMOSOME 1; CHROMOSOME 2; CHROMOSOME 6; ECTROMELIA VIRUS; FEMALE; GENE LOCATION; HOST RESISTANCE; IMMUNITY; INFECTION RESISTANCE; LEUKOCYTE ACTIVATION; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RODENT DISEASE; SPLEEN CELL;

ANIMALS; ANTIGENS, SURFACE; CHEMOTAXIS, LEUKOCYTE; CHROMOSOME MAPPING; COMPLEMENT C5; CROSSES, GENETIC; ECTROMELIA, INFECTIOUS; FEMALE; HEPATITIS, ANIMAL; IMMUNITY, NATURAL; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LEUKOCYTE COUNT; LINKAGE (GENETICS); MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICROSATELLITE REPEATS; NECROSIS; SPLEEN;

EID: 0030945271     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Blanden RV: Mechanisms of recovery from a generalized viral infection: mousepox. I. The effects of anti-thymocyte serum. J Exp Med 1970, 132:1035-1054
2. Hapel AJ, Bablanian R, Cole GA: Inductive requirements for the generation of virus-specific T lymphocytes. III. Production of target cells lysable by poxvirus-specific and allospecific cytotoxic T lymphocytes with membrane fragments bearing viral and H-2 antigens, J Immunol 1980, 124:1997-2003
3. Kees U, Blanden RV: A single genetic element in H-2K affects mouse T-cell antiviral function in poxvirus infection. J Exp Med 1976, 143:450-455
4. Tsuru S, Kitani H, Seno M, Abe M, Zinnaka Y, Nomoto K: Mechanism of protection during the early phase of a generalized viral infection. I. Contribution of phagocytes to protection against ectromelia virus. Gen Virol 1983, 64:2021-2026
5. Blanden RV, Gardner ID: The cell-mediated immune response to ectromelia virus infection. I. Kinetics and characteristics of the primary effector T cell response in vivo. Cell Immunol 1976, 22:271-282
6. Zinkernagel RM, Althage A: Antiviral protection by virus-immune cytotoxic T cells: infected target cells are lysed before infectious virus progeny is assembled. J Exp Med 1977, 145:644-651
7. Buller RML, Palumbo GJ: Poxvirus pathogenesis. Microbiol Rev 1991, 55:80-122
8. Gooding LR: Virus proteins that counteract host immune defenses. Cell 1992, 71:5-7
9. Traktman P: Poxviruses: an emerging portrait of biological strategy. Cell 1990, 62:621-626
10. Turner PC, Moyer RW: The molecular pathogenesis of poxviruses. Curr Top Microbiol Immunol 1990, 163:125-151
11. O'Neill HC, Blanden RV: Mechanisms determining innate resistance to ectromelia virus infection in C57BL mice. Infect Immun 1983, 41:1391-1394
12. Brownstein DG, Bhatt PN, Gras L: Ectromelia virus replication in major target organs of innately resistant and susceptible mice after intravenous infection. Arch Virol 1993, 129:65-75
13. Jacoby RO, Bhatt PN: Mousepox in inbred mice innately resistant or susceptible to lethal infection with ectromelia virus. II. Pathogenesis, Lab Anim Sci 1987, 37:16-22
14. Schell K: Studies on the innate resistance of mice to infection with mousepox. I. Resistance and antibody production, Aust J Exp Biol Med Sci 1960, 38:271-283
15. Jacoby RO, Bhatt PN, Brownstein DG: Evidence that NK cells and Interferon are required for genetic resistance to lethal infection with ectromelia virus. Arch Virol 1989, 108:49-58
16. Brownstein DG, Gras L: Chromosome mapping of Rmp-4, a gonad-dependent gene encoding host resistance to mousepox. J Virol 1995, 69:6958-6964
17. Wallace GD, Buller RML, Morse HC III: Genetic deter- minants of resistance to ectromelia (mousepox) virus-induced mortality. J Virol 1985, 55:890-891
18. Brownstein DG, Bhatt PN, Gras L, Jacoby RO: Chromosomal locations and gonadal dependence of genes that mediate resistance to ectromelia (mousepox) virus-induced mortality. J Virol 1991, 65:1946-1951
19. Brownstein DG, Bhatt PN, Gras L, Budris T: Serial backcross analysis of genetic resistance to mousepox using marker loci for Rmp-2 and Rmp-3. J Virol 1992, 66:7073-7079
20. Delano ML, Brownstein DG: Innate resistance to lethal mousepox is genetically linked to the NK gene complex on chromosome 6 and correlates with early restriction of virus replication by cells with an NK phenotype. J Virol 1995, 69:5875-5877
21. Bhatt PN, Jacoby RO, Gras L: Mousepox in inbred mice innately resistant or susceptible to lethal infection with ectromelia virus. IV, Studies with the Moscow strain. Arch Virol 1988, 100:221-230
22. Hogan B, Beddington R, Costantini F, Lacy E: Analysis of Transgenic Mice: Manipulating the Mouse Embryo. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press, 1994, pp 291-326
23. Krieg P, Amtmann E, Sauer G: The simultaneous extraction of high-molecular-weight DNA and of RNA from solid tumors, Anal Biochem 1983, 134:288-294
24. Reed LJ, Muench H: A simple method of estimating fifty percent endpoints. Am J Hyg 1938, 27:493-497
25. Flaherty L: Congenic strains. The Mouse in Biomedical Research, Edited by HL Foster, JD Small, JD Fox. New York, Academic Press, 1981, pp 215-222
26. Brownstein D, Bhatt PN, Jacoby RO: Mousepox in inbred mice innately resistant or susceptible to lethal infection with ectromelia virus. V. Genetics of resistance to the Moscow strain. Arch Virol 1989, 107:35-41
27. Dietrich W, Katz H, Lincoln SE, Shin HS, Friedman J, Dracopoli NC, Lander ES: A genetic map of the mouse suitable for typing intraspecific crosses, Genetics 1992, 131:423-447
28. Schell K: Studies on the innate resistance of mice to infection with mousepox, II. Route of inoculation and resistance; and some observations on the inheritance of resistance. Aust J Exp Biol Med Sci 1960, 33:289-299
29. Cook MG: Anatomy. The Mouse in Biomedical Research. Edited by HL Foster, JD Small, JD Fox. New York, Academic Press, 1983, pp 102-120
30. Yokoyama WM, Ryan JC, Hunter JJ, Smith HR, Stark M, Seaman WE: cDNA cloning of mouse NKR-P1 and genetic linkage with LY-49: identification of a natural killer cell gene complex on mouse chromosome 6. J immunol 1991, 147:3229-3236
31. Giorda R, Weisberg EP, i.p. TK, Trucco M: Genomic structure and strain-specific expression of the natural killer cell receptor NKR-P1. J Immunol 1992, 149:1957-1963
32. Ryan JC, Turck J, Niemi EC, Yokoyama WM, Seaman WE: Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules. J Immunol 1992, 149:1631-1635
33. Giorda R, Rudert WA, Vavassori C, Chambers WH, Hiserodt JC, Trucco M: NKR-P1, a signal transduction molecule on natural killer cells, Science 1990, 249:1298-1300
34. Yokoyama WM: Natural killer cell receptors specific for major histocompatibility complex class I molecules. Proc Natl Acad Sci USA 1995, 92:3081-3085
35. + cells in the liver of mice. J Exp Med 1994, 180:699-704
36. Ohteki T, Okuyama R, Seki S, Abo T, Sugiura K, Kusumi A, Ohmori T, Watanabe H, Kumagai K: Age-dependent increase of extrathymic T cells in the liver and their appearance in the periphery of older mice. J Immunol 1992, 149:1562-1570
37. + αβ T cells with intermediate TCR induced in the liver of mice by IL-12, J Immunol 1995, 154:4333-4340
38. + T cells by non-major histocompatibility complex-encoded class I-like molecules expressed on bone marrow-derived cells. Proc Natl Acad Sci USA 1995, 92:1200-1204
39. Stroynowski I: Molecules related to class-I major histocompatibility complex antigens. Annu Rev Immunol 1990, 8:501-530
40. + T lymphocytes. Science 1995, 268:863-865
41. Pamer EG, Wang CR, Flaherty L, Lindahl KF, Bevan MJ: H-2M3 presents a Listeria monocytogenes peptide to cytotoxic T lymphocytes. Cell 1992, 70:215-223
42. Imani F, Soloski MJ: Heat shock proteins can regulate expression of the Tla region-encoded class Ib molecule Qa-1. Proc Natl Acad Sci USA 1991, 88:10475-10479
43. Yoshimoto T, Paul WE: CD4 pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3, J Exp Med 1994, 179:1285-1295
44. Ohtsuka K, Sato K, Watanabe H, Kimura M, Asakura H, Abo T: Unique order of the lymphocyte subset induction in the liver and intestine of mice during Listeria monocytogenes infection. Cell Immunol 1995, 161:112-124
45. - thymocytes with specific lymphokine secretion. Eur J Immunol 1993, 23:307-310
46. D'Eustachio P, Kristensen T, Wetsel RA, Ribtet R, Taylor BA, Tack BF: Chromosomal location of the genes encoding complement components C5 and factor H in the mouse. J Immunol 1986, 137:3990-3995
47. Rosenberg LT, Tachibana DK: Mice deficient in C5. Prog Allergy 1986, 39:169-191
48. Gervais F, Stevenson M, Skamene E: Genetic control of resistance to Listeria monocytogenes: regulation of leukocyte inflammatory responses by the He locus. J Immunol 1984, 132:2078-2083
49. Gervais F, Desforges C, Skamene E: The C5-sufficient A/J congenic mouse strain: inflammatory response and resistance to Listeria monocytogenes. J Immunol 1989, 142:2057-2060
50. Stevenson MM, Gervais F, Skamene E: Natural resistance to listeriosis: role of host inflammatory responsiveness. Clin Invest Med 1984, 7:297-301
51. Watson ML, Kingsmore SF, Johnston GI, Siegelman MH, Le Beau MM, Lemons RS, Bora NS, Howard TA, Weissman IL, McEver RP, Seldin MF: Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1. J Exp Med 1990, 172:263-272
52. Kelner GS, Kennedy J, Bacon KB, Kleyensteuber S, Largaespada DA, Jenkins NA, Copeland NG, Bazan JF, Moore KW, Schall TJ, Zlotnik A: Lymphotactin: a cytokine that represents a new class of chemokine, Science 1994, 266:1395-1399
53. McEver RP: Selectins. Curr Opin Immunol 1994, 6:75-84
54. Tedder TF, Penta AC, Levine HB, Freedman AS: Expression of the human leukocyte adhesion molecule, LAM1: identity with the TQ1 and Leu-8 differentiation antigens, J Immunol 1990, 144:532-540
55. Larsen E, Celi A, Gilbert GE, Furie BC, Erban JK, Bonfanti R, Wagner DD, Furie B: PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell 1989, 59:305-312
56. Bevilacqua MP, Pober JS, Mendrick DL, Cotran RS, Gimbrone MA J.: Identification of an inducible endothelial-leukocyte adhesion molecule. Proc Natl Acad Sci USA 1987, 84:9238-9242
57. Bevilacqua MP, Stengelin S. Gimbrone MA Jr, Seed B: Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science 1989, 243:1160-1165
58. Ley K, Tedder TF: Leukocyte interactions with vascular endothelium: new insights into selectin-mediated attachment and rolling. J Immunol 1995, 155:525-528
59. Bullard DC, Kunkel EJ, Kubo H, Hicks MJ, Lorenzo I, Doyle NA, Doerschuk CM, Ley K, Beaudet AL: Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. J Exp Med 1996, 183:2329-2336
60. Siegelman MH, Cheng IC, Weissman IL, Wakeland EK: The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: role of the EGF domain in endothelial binding. Cell 1990, 61:611-622
61. Karupiah G, Frederickson TN, Holmes KL, Khairallah LH, Buller RML: Importance of interferons in recovery from mousepox. J Virol 1993, 67:4214-4226
62. + spleen cells contain γ Interferon (IFN-γ) gene transcripts in the early, sex-dependent production of IFN-γ after picornavirus infection. J Virol 1990, 64:4407-4413
63. + T cells upon NKR-P1 cross-linking. J Exp Med 1996, 183:2391-2396