Hormone-specific alterations of T4, T3, and reverse T3 metabolism with recent ethanol abstinence in humans

American Journal of Physiology - Endocrinology and Metabolism

Volumn 272, Issue 2 35-2, 1997, Pages

  Kaptein, E M ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

3,5,3' triiodothyronine; alcohol withdrawal; alcoholism; reverse triiodothyronine; thyroid hormones; thyroxine

Indexed keywords

3,3',5' TRIIODOTHYRONINE; ALCOHOL; LIOTHYRONINE; THYROXINE;

ADULT; ALCOHOL WITHDRAWAL; ALCOHOLISM; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HORMONE BINDING; HORMONE TRANSPORT; HUMAN; LIOTHYRONINE BLOOD LEVEL; LIOTHYRONINE METABOLISM; MALE; PRIORITY JOURNAL; THYROXINE BLOOD LEVEL; THYROXINE METABOLISM;

EID: 0030945259     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1997.272.2.e191     Document Type: Article

References (32)

1. Baraona, E., M. A. Leo, S. A. Borowsky, and C. S. Lieber. Pathogenesis of alcohol-induced accumulation of protein in the liver. J. Clin. Invest. 60: 546-554, 1977.
2. Bauer, A. G. C., J. H. P. Wilson, S. W. J. Lamberts, R. Docter, G. Hennemann, and T. J. Visser. Handling of iodothyronines by the liver and kidney in patients with chronic liver disease. Acta Endocrinol. 116: 339-346, 1987.
3. Baumgartner, A., A. Heyne, A. Campos-Barros, R. Kohler, F. Muller, H. Meinhold, H. Rommelspacher, and J. Wolffgramm. Hypothalamic-pituitary-thyroid axis in chronic alcoholism. II. Deiodinase activities and thyroid hormone concentrations in brain and peripheral tissues of rats chronically exposed to ethanol. Alcohol. Clin. Exp. Res. 18: 295-304, 1994.
4. Baumgartner, A., H. Rommelspacher, M. Otto, L. G. Schmidt, I. Kurten, K.-J. Graf, A. Campos-Barros, and W. Platz. Hypothalamic-pituitary-thyroid (HPT) axis in chronic alcoholism. I. HPT axis in chronic alcoholics during withdrawal and after 3 weeks of abstinence. Alcohol. Clin. Exp. Res. 18: 284-294, 1994.
5. Benvenga, S., R. E. Gregg, and J. Robbins. Binding of thyroid hormones to human plasma lipoproteins. J. Clin. Endocrinol. 67: 6-16, 1988.
6. 131I-triiodothyronine accumulation and degradation in ethanol-treated and control rats. Life Sci. 8: 267-275, 1969.
7. Carmichael, F. J., H. Orrego, V. Saldivia, and Y. Israel. Effect of propylthiouracil on the ethanol-induced increase in liver oxygen consumption in awake rats. Hepatology 18: 415-421, 1993.
8. 131I-labeled L-thyroxine in man: observations of subjects with normal and decreased serum thyroxine-binding globulin. J. Clin. Invest. 45: 939-949, 1966.
9. Crabb, D. W. The liver. In: Recent Developments in Alcoholism, edited by M. Galanter. New York: Plenum, 1993, vol. 11, p. 207-230.
10. 4 uptake in humans are inhibited by fructose. Am. J. Physiol. 266 (Endocrinol. Metab. 29): E768-E775, 1994.
11. De Jong, M., T. J. Visser, B. F. Bernard, R. Docter, R. A. Vos, G. Hennemann, and E. P. Krenning. Transport and metabolism of iodothyronines in cultured human hepatocytes. J. Clin. Endocrinol. Metab. 77: 139-143, 1993.
12. Gavin, L. A., M. Moeller, F. A. McMahon, J. N. Castle, R. Gulli, and R. R. Cavalieri. Carbohydrate feeding increases total body and specific tissue 3,5,3′-triiodothyronine neogenesis in the rat. Endocrinology 123: 1075-1081, 1988.
13. Hadengue, A., R. Moreau, S. S. Lee, C. Gaudin, B. Rueff, and D. Lebrec. Liver hypermetabolism during alcohol withdrawal in humans: role of sympathetic overactivity. Gastroenterology 94: 1047-1052, 1988.
14. Hays, M. T., R. A. McGuire, J. T. Hoogeveen, and K. N. Diezeraad. Measurement method for radioactive thyroxine, triiodothyronine, iodide, and iodoprotein in samples with low activity. J. Nucl. Med. 21: 225-232, 1980.
15. 3 disposal in normal subjects. Acta Endocrinol. 82: 92-97, 1976.
16. Hoek, J. B., and T. F. Taraschi. Cellular adaptation to ethanol. Trends Biochem. Sci. 13: 269-274, 1988.
17. Israel, Y., L. Videla, A. MacDonald, and J. Bernstein. Metabolic alterations produced in the liver by chronic ethanol administration. Biochem. J. 134: 523-529, 1973.
18. Kaptein, E. M. Thyroid hormone metabolism in illness. In: Thyroid Hormone Metabolism, Basic and Clinical Endocrinology Series, edited by G. Hennemann. New York: Dekker, 1986, vol. 8, p. 297-333.
19. Kaptein, E. M., M. T. Hoopes, D. C. Ferguson, E. C. Satyadi, and M. Akmal. Comparison of serum reverse triiodothyronine distribution and metabolism in normal dogs and humans. Endocrinology 126: 2003-2014, 1990.
20. Kaptein, E. M., J. S. Kaptein, E. I. Chang, P. M. Egodage, J. T. Nicoloff, and S. G. Massry. Thyroxine transfer and distribution in critical nonthyroidal illnesses, chronic renal failure, and chronic ethanol abuse. J. Clin. Endocrinol. Metab. 65: 606-616, 1987.
21. Kaptein, E. M., G. E. Moore, D. C. Ferguson, and M. Hoenig. Thyroxine and triiodothyronine distribution and metabolism in thyroxine-replaced athyreotic dogs and normal humans. Am. J. Physiol. 264 (Endocrinol. Metab. 27): E90-E100, 1993.
22. Kawasaki, R., F. J. Carmichael, G. Giles, V. Saldivia, Y. Israel, and H. Orrego. Effects of propylthiouracil and methimazole on splanchnic hemodynamics in awake and unrestrained rats. Hepatology 10: 273-278, 1989.
23. Lieber, C. S. Hepatic, metabolic and toxic effects of ethanol: 1991 update. Alcohol. Clin. Exp. Res. 15: 573-592, 1991.
24. LoPresti, J. S., D. Gray, and J. T. Nicoloff. Influence of fasting and refeeding on 3,3′,5′-triiodothyronine metabolism in man. J. Clin. Endocrinol. Metab. 72: 130-136, 1991.
25. Mendel, C. M., R. R. Cavalieri, and R. A. Weisiger. Uptake of thyroxine by the perfused rat liver: implications for the free hormone hypothesis. Am. J. Physiol. 255 (Endocrinol. Metab. 18): E110-E119, 1988.
26. 125I. J. Clin. Invest. 46: 762-777, 1967.
27. Pignon, J.-P., N. C. Baily, E. Baraona, and C. S. Lieber. Fatty acid-binding protein: a major contributor to the ethanol-induced increase in liver cytosolic proteins in the rat. Hepatology 7: 865-871, 1987.
28. Poso, A. R., and P. Hirsimaki. Inhibition of proteolysis in the liver by chronic ethanol feeding. Biochem. J. 273: 149-152, 1991.
29. Shank, M. L., P. S. Singh, B. B. Blivaiss, M. A. Kabir, K. Williams, and B. N. Premachandra. Ethanol feeding and thyroid hormone monodeiodination. Metab. Clin. Exp. 33: 667-671, 1984.
30. Teschke, R., F. Moreno, E. Heinen, J. Herrmann, H.-L. Kruskemper, and G. Strohmeyer. Hepatic thyroid hormone levels following chronic alcohol consumption: direct experimental evidence in rats against the existence of a hyperthyroid hepatic state. Hepatology 3: 469-474, 1983.
31. Van der Heijden, J. T. M., E. P. Krenning, H. van Toor, G. Hennemann, and R. Docter. Three-compartmental analysis of effects of D-propranolol on thyroid hormone kinetics. Am. J. Physiol. 255 (Endocrinol. Metab. 18): E80-E86, 1988.
32. 3 syndrome. Am. J. Physiol. 251 (Endocrinol. Metab. 14): E156-E163, 1986.