Nimodipine at a dose that slows ABR latencies does not protect the ear against noise

Hearing Research

Volumn 106, Issue 1-2, 1997, Pages 179-183

  Ison, James R ^a   Payman, Gary H ^a   Palmer, Michael J ^a   Walton, Joseph P ^b  

^a UNIVERSITY OF ROCHESTER   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

ABR latency; auditory threshold; calcium channel; mouse; noise exposure

Indexed keywords

NIMODIPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY THRESHOLD; CONTROLLED STUDY; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; MALE; MOUSE; NOISE; NOISE INJURY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ACOUSTIC STIMULATION; ADMINISTRATION, ORAL; ANALYSIS OF VARIANCE; ANIMALS; AUDITORY THRESHOLD; CALCIUM CHANNEL BLOCKERS; DISEASE MODELS, ANIMAL; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FEMALE; HEARING LOSS, NOISE-INDUCED; MALE; MICE; MICE, INBRED C57BL; NIMODIPINE; RANDOM ALLOCATION;

EID: 0030945234     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5955(96)00216-X     Document Type: Article

References (26)

1. Axelsson, A. and Vertes, D. (1982) Histological findings in cochlear vessels after noise. In: R.P. Hamernik, D. Henderson, and R. Salvi (Eds.), New Perspectives on Noise-Induced Hearing Loss. Raven Press, New York, 1982.
2. Bielenberg, G.W., Burniol, M., Rosen, R. and Klaus, W. (1990) Effects of nimodipine on infarct size and cerebral acidosis after middle cerebral artery occlusion in the rat. Stroke 21 (Suppl. IV), 90-92.
3. 2+ antagonist, reverses the negative summating potential recorded for the guinea pig cochlea. Hear. Res. 46, 277-288.
4. Choi, D.W. (1994) Calcium and excitotoxic neuronal injury. Ann. NY Acad. Sci. 747, 162-171.
5. Coleman, J.K.M., Dengerink, H.A. and Wright, J.W. (1991). Effects of hydroxyethyl starch, nimodipine, and propylene glycol on cochlear blood flow. Otolaryngol. Head Neck Surg. 105, 840-844.
6. Cotran, R.S., Kumar, V. and Robbins, S.L. (1994) Pathologic Basis of Disease, 5th edn., W.B. Saunders, Philadelphia, PA.
7. De Jong, G.I., de Weerd, H., Schuurman, H., Traber, J. and Luiten, P.G.M. (1990) Microvascular changes in aged rat forebrain. Effects of chronic nimodipine treatment. Neurobiol. Aging 11, 381-389.
8. Dengerink, H.A. and Wright, J.W. (1988) Physiology of the ear. In: A.F. Jahn and J. Santos-Sacchi (Eds.), Circulation of the Inner Ear. Raven Press, New York, pp. 328-340.
9. Dubinsky, J.M. (1993) Examination of the role of calcium in neuronal death. Ann. NY Acad. Sci. 679, 34-42.
10. Ehrenberger, K. and Felix, D. (1995) Receptor pharmacological models for inner ear therapies with emphasis on glutamate receptors: a survey. Acta Otolaryngol. 115, 236-240.
11. Jacewicz, M., Brint, S., Tanabe, J. and Pulsinelli, W.A. (1990) Continuous nimodipine treatment attenuates cortical infarction in rats subjected to 24 hours of focal cerebral ischemia. J. Cereb. Blood Flow Metab. 10, 89-96.
12. Lim, D.J. (1976) Ultrastructural cochlear changes following acoustic hyperstimulation and ototoxicity. Ann. Oto. Rhino. Laryngol. 85, 740-751.
13. + current in isolated outer hair cells of the guinea pig. Hear. Res. 88, 36-46.
14. Meyer, P., Werner, E., Schmidt, R., Grutzmacher, W., Gehrig, W. and Seuter, F. (1994) Beeinflussung der kochlearen Durchblutung des Meerschweinchens durch Nimodipin. Arzneimittel-Forschung. 44, 1108-1111.
15. Moller, A.R. (1994) Neural generators of auditory evoked potentials. Ch. 2. In: J.T. Jacobson (Ed.), Principles and Application in Auditory Evoked Potentials. Allyn and Bacon, New York, pp. 23-46.
16. Rami, A. and Krieglstein, J. (1994) Neuronal protective effects of calcium antagonists in cerebral ischemia. Life Sci. 55, 2105-2113.
17. Saunders, J.C., Dear, S.P. and Schneider, M.E. (1985) The anatomical consequences of acoustic injury: a review and tutorial. J. Acoust. Soc. Am. 78, 833-860.
18. Scheibe, F., Haupt, H. and Ludwig, C. (1992) Intensity-dependent changes in oxygenation of cochlear perilymph during acoustic exposure. Hear. Res. 63, 19-25.
19. Scheibe, F., Haupt, H. and Ludwig, C. (1993) Intensity-related changes in cochlear blood flow in the guinea pig during and following acoustic exposure. Eur. Arch. Otorhinolaryngol. 250, 281-285.
20. Seidman, M.D., Shivapuja, B.G. and Quirk, W.S. (1993) The protective effects of allopurinol and superoxide dismutase on noise-induced cochlear damage. Otolaryngol. Head Neck Surg. 109, 1052-1056.
21. Siesjo, B.K. (1994) Calcium-mediated processes in neuronal degeneration. Ann. NY Acad. Sci. 747, 140-161.
22. Spoendlin, H.H. (1976) Anatomical changes following various noise exposures. In: D. Henderson, R.P. Hamernik, D.S. Dosanjh and J.H. Mills (Eds.), Effects of Noise on Hearing, Raven Press, New York, pp. 69-89.
23. Teasdale, G., Mendelow, A.D., Graham, D.I., Harper, A.M. and McCulloch, J. (1990) Efficacy of nimodipine in cerebral ischemia or hemorrhage. Stroke 21 (Suppl. IV), 123-125.
24. Thorne, P.R. and Nuttall, A.L. (1987) Laser Doppler measurements of cochlear blood flow during loud sound exposure in the guinea pig. Hear. Res. 27, 1-10.
25. Thorne, P.R. and Nuttall, A.L. (1989) Alterations in oxygenation of cochlear endolymph during loud sound exposure. Acta Otolaryngol. 107, 71-79.
26. Yamane, H., Nakai, Y., Konishi, K., Sakamoto, H., Iguchi, H., Nakagawa, T. and Morinaka, K. (1991) Cochlear strial blood circulation. Acta Otolaryngol. Suppl. 481, 182-186.