A new cytotoxic phenylthiazoline, 4-methylaeruginoic acid, from Streptomyces sp. KCTC 9303

Journal of Antibiotics

Volumn 50, Issue 3, 1997, Pages 256-258

  Ryoo, In Ja ^a   Song, Kyung Sik ^b   Kim, Jong Pyung ^a   Kim, Won Gon ^a   Koshino, Hiroyuki ^c   Yoo, Ick Dong ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Kyungpook National University   (South Korea)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHYLAERUGINOIC ACID; CYTOTOXIC AGENT; PHENYLTHIAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STREPTOMYCES;

EID: 0030944843     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.50.256     Document Type: Article

References (9)

1. YAMADA, Y.; N. SEKI, T. KITAHARA, M. TAHASHI & M. MATSUI: The structures and synthesis of aeruginoic acid (2-o-hydroxyphenyl-thiazole-4-carboxylic acid). Agr. Biol. Chem. 34: 780-783, 1970
2. Cox, C. D.; K. L. RINEHART, Jr., M. L. MOORH & J. C. COOK, Jr.: Pyochelin: novel structure of an iron-chelating growth promoter for Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. U.S.A. 78: 4256-4260, 1981
3. CARMI, R.; S. CARMELI, E. LEVY & F. J. GOUGH: (+)-(S)-Dihydroaeruginoic acid, an inhibitor of Septoria tritici and other phytopathogenic fungi and bacteria, produced by Pseudomonas fluorescens. J. Nat. Prod. 57: 1200-1205, 1994
4. BUKOBITS, G. J.; N. MOHR & H. BUDZIKIEWIEZ: 2-Phenylthiazol-Derivate aus Pseudomonas cepacia. Z. Naturforsch 37b: 877-880, 1982
5. SHINDO, K.; A. TAKENAKA, T. NOGUCHI, Y. HAYAKAWA & H. SETO: Thiazostatin A and thiazostatin B, new antioxidants produced by Streptomyces tolurosus. J. Antibiotics 42: 1526-1529, 1989
6. NAEGELI, H.-U. & H. ZäHNER: Stoffwechselprodukte von Mikroorganismen Ferrithiocin. Helv. Chim. Acta 63: 1400-1406, 1980
7. SHIRLING, E. B. & D. GOITLIEB: Methods for characterization of Streptomyces species. Int. J. Syst. Bacteriol. 16: 313-340, 1966
8. WILLKER, W. & D. LEIBFRITZ: Gradient selection in inverse heteronuclear correlation spectroscopy. Magn. Reson. Chem. 31:287-292, 1993
9. MONKS, A.; D. SCUDIERO, P. SKEHAN, R. SHOEMAKER, K. PAUL, D. VISTICA, C. HOES, J. LANGLEY, P. CRONISE, A. VAIGRO-WOLV, M. GRAY-GOODRICH, H. CAMPBELL, J. MAYO & M. BOYD: Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J. Nat. Cancer Inst. 83: 757-766, 1991