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Volumn 38, Issue 20, 1997, Pages 3651-3654

An approach to enantiomerically pure inverse γ-turn mimetics for use in solid-phase synthesis

Author keywords

[No Author keywords available]

Indexed keywords

ETHYLENE OXIDE DERIVATIVE;

EID: 0030944795     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00692-8     Document Type: Article
Times cited : (19)

References (33)
  • 1
    • 0343762943 scopus 로고    scopus 로고
    • Present address: Organic Chemistry, Umeå University, S-901 87 Umeå, Sweden
    • Present address: Organic Chemistry, Umeå University, S-901 87 Umeå, Sweden.
  • 2
    • 0002340017 scopus 로고
    • Obstacles to drug development from peptide leads
    • Clark, C. R.; Moos, W. R., Eds.; Ellis Harwood Ltd.-Halstead Press: Chichester, England
    • Plattner, J. J.; Norbeck, D. W. Obstacles to drug development from peptide leads. In Drug discovery technologies; Clark, C. R.; Moos, W. R., Eds.; Ellis Harwood Ltd.-Halstead Press: Chichester, England, 1989; pp. 92-126.
    • (1989) Drug Discovery Technologies , pp. 92-126
    • Plattner, J.J.1    Norbeck, D.W.2
  • 3
    • 0000788606 scopus 로고
    • Peptide backbone modifications: A structure activity analysis of peptides containing amide bond surrogates, conformational constraints, and related backbone replacements
    • Weinstein, B., Ed.; Marcel Dekker, Inc.: New York & Basel
    • Spatola, A. P. Peptide backbone modifications: A structure activity analysis of peptides containing amide bond surrogates, conformational constraints, and related backbone replacements. In Chemistry and Biochemistry of Amino Acids, Peptides, and Proteins; Weinstein, B., Ed.; Marcel Dekker, Inc.: New York & Basel, 1983; Vol. 7; pp. 267-357.
    • (1983) Chemistry and Biochemistry of Amino Acids, Peptides, and Proteins , vol.7 , pp. 267-357
    • Spatola, A.P.1
  • 10
    • 0021779081 scopus 로고
    • A. Turns in peptides and proteins
    • Anfinsen, C. B.; Edsall, J. T.; Richards, F. M., Eds.; Academic Press: Orlando, Florida
    • Rose, G. D.; Gierasch, L. M.; Smith, J. A. Turns in peptides and proteins. In Advances in Protein Chemistry; Anfinsen, C. B.; Edsall, J. T.; Richards, F. M., Eds.; Academic Press: Orlando, Florida, 1985; Vol. 37; pp. 1-109.
    • (1985) Advances in Protein Chemistry , vol.37 , pp. 1-109
    • Rose, G.D.1    Gierasch, L.M.2    Smith, J.3
  • 21
    • 0343762938 scopus 로고    scopus 로고
    • note
    • The torsional angles for the second residue differentiates between a γ-turn (Φ = 70 to 85°, Ψ = -60 to -70°) and an inverse γ-turn (Φ = -70 to -85°, Ψ = 60 to 70°), cf. reference 10. An open turn has been used for a situation in which no hydrogen bond exists and the Φ, Ψ-angles are then within 30° of the cited ones.
  • 25
    • 0343326981 scopus 로고    scopus 로고
    • InStar Software AB, IDEON Research Park, S-223 70 Lund, Sweden
    • InStar Software AB, IDEON Research Park, S-223 70 Lund, Sweden.
  • 33
    • 0342457592 scopus 로고    scopus 로고
    • note
    • 1H NMR spectrum of 1 and to confirm the configuration of the six-membered ring.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.