Synthesis of polycarpine, a cytotoxic sulfur-containing alkaloid from the ascidian Polycarpa Aurata, and related compounds

Tetrahedron Letters

Volumn 38, Issue 20, 1997, Pages 3581-3584

  Radchenko, Oleg S ^a   Novikov, Vyacheslav L ^a   Willis, Richard H ^b   Murphy, Peter T ^b   Elyakov, George B ^a  

^a RUSSIAN ACADEMY OF SCIENCES   (Russian Federation)

^b AUSTRALIAN INSTITUTE OF MARINE SCIENCE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; CYTOSTATIC AGENT; POLYCARPINE; RNA DIRECTED DNA POLYMERASE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; AVIAN MYELOBLASTOSIS VIRUS; CELL CULTURE; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; EHRLICH ASCITES TUMOR CELL; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA; MOUSE; NONHUMAN; REACTION ANALYSIS; ROUS SARCOMA ONCOVIRUS; TUMOR CELL;

EID: 0030944794     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00668-0     Document Type: Article

References (10)

1. Fedoreyev, S.A.; Radchenko, O.S.; Novikov, V.L.; Isakov V.V.; Ilyin, S.G.; Popov, A.M.; Elyakov, G.B.; Murphy, P.T.; Willis, R.H.; Baker, J.T. Proc. 8th Inter. Symp. on Marine Nat. Prod., Santa Cruz de Tenerife, Tenerife, Canary Islands, Spain, 1995, p. 196-197.
2. Kang, H.; Fenical, W. Tetrahedron Lett., 1996, 37, 2369-2372.
3. Abbas, S.A.; Hossain, M.B.; van der Helm, D.; Schmitz, F.J.; Laney, M.; Cabuslay, R.; Schatzman, R.C. J. Org. Chem., 1996, 61, 2709-2712.
4. Faulkner, D.J. Nat. Prod. Rep., 1988, 5, 613-663; Faulkner, D.J. ibid., 1995, 12, 223-268.
5. Faulkner, D.J. Nat. Prod. Rep., 1988, 5, 613-663; Faulkner, D.J. ibid., 1995, 12, 223-268.
6. Lindquist, N.; Fenical, W. Tetrahedron Lett., 1990, 31, 2389-2392.
7. Davidson, B.S., Molinski, T.F., Barrows, L.R., Ireland, C.M. J. Am. Chem. Soc., 1991, 113, 4709-4710.
8. Davidson, B.S. Chem. Rev., 1993, 93, 1771-1791.
9. Fu, X., Schmitz, F.J.; Govindan, M.; Abbas, S.A.; Hanson, K.M.; Horton, P.A.; Crews, P.; Laney, M.; Schatzman, R.C. J. Nat. Prod., 1995, 58, 1384-1391.
10. +, 0.1), 235(13), 234(20), 233(100), 232(4), 218(12), 204(15), 203(55), 202(21), 194(2), 193(6), 192(28), 188(21), 152(29).