Ang II modifies cardiomyocyte function via extracardiac and intracardiac neurons: In situ and in vitro studies

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 272, Issue 3 41-3, 1997, Pages

  Horackova, Magda ^a   Armour, J Andrew ^a,b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

adult guinea pig cardiomyocytes; AT1 receptors; cardiac chronotropism; cardiac inotropism; culture; intracellular calcium transients; intrinsic cardiac neuron; middle cervical ganglion neuron; stellate ganglion neuron

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; LOSARTAN POTASSIUM; TIMOLOL;

ADRENERGIC SYSTEM; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CURRENT; CERVICAL GANGLION; CHRONOTROPISM; CONTROLLED STUDY; FEMALE; GUINEA PIG; HEART CONTRACTION; INOTROPISM; MALE; MUSCLE FORCE; NONHUMAN; PRIORITY JOURNAL; STELLATE GANGLION;

EID: 0030944149     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1997.272.3.r766     Document Type: Article

References (31)

1. Allen, I. S., N. M. Cohen, R. S. Dhallan, S. T. Gaa, W. J. Lederer, and T. B. Rogers. Angiotensin II increases spontaneous contractile frequency and stimulates calcium current in cultured neonatal rat heart myocytes: insights into the underlying biochemical mechanisms. Circ. Res. 62: 524-534, 1988.
2. Ardell, J. L., C. K. Butler, F. M. Smith, D. A. Hopkins, and J. A. Armour. Activity of in vivo atrial and ventricular neurons in chronically decentralized canine hearts. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H713-H721, 1991.
3. Armour, J. A., M. H. Huang, and F. M. Smith. Peptidergic modulation of in situ canine intrinsic cardiac neurons. Peptides 14: 191-202, 1993.
4. Baker, K. M., and J. F. Aceto. Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells. Am. J. Physiol. 259 (Heart Circ. Physiol. 28): H610-H618, 1990.
5. Baker, K. M., and H.A. Singer. Identification and characterization of guinea pig angiotensin II ventricular and atrial receptors: coupling to inositol phosphate production. Circ. Res. 62: 896-904, 1988.
6. Bescond, J., P. Bois, J. Petit-Jacques, and J. Lenfant. Characterization of an angiotensin-II-activated chloride current in rabbit sino-atrial cells. J. Membr. Biol. 140: 153-161, 1994.
7. Casträn, E., M. Kurihara, J. S. Gutkind, and J. M. Saavedra. Specific angiotensin II binding sites in rat stellate and superior cervical ganglia. Brain Res. 422: 347-351, 1987.
8. Dostal, D. E., and K. M. Baker. Evidence for a role of an intracardiac renin-angiotensin system in normal and failing hearts. Trends Cardiovasc. Med. 3: 67-74, 1993.
9. Dostal, D. E., K. N. Rothblum, K. M. Conrad, G. R. Cooper, and K. M. Baker. Detection of angiotensin I and II in cultured rat cardiac myocytes and fibroblasts. Am. J. Physiol. 263 (Cell Physiol. 32): C851-C863, 1992.
10. Doursout, M.-F., J. E. Chelly, C. J. Hartley, J. Szilagyi, J.-L. Montastruc, and J. P. Buckley. Regional blood flows and cardiac function changes induced by angiotensin II in conscious dogs. J. Pharmacol. Exp. Ther. 246: 591-596, 1988.
11. 2+ modulation. Circ. Res. 78: 302-311, 1996.
12. 1 receptors mediate a positive inotropic effect of angiotensin II in guinea pig atria. Eur. J. Pharmacol. 245: 63-66, 1993.
13. Freer, R. J., A. J. Pappano, M. J. Peach, K. T. Bing, M. J. McLean, S. Vogel, and N. Sperelakis. Mechanism for the positive inotropic effect of angiotensin II on isolated cardiac muscle. Circ. Res. 39: 178-183, 1976.
14. Fujii, A. M., and S. F. Vatner. Direct versus indirect pressor and vasoconstrictor actions of angiotensin in conscious dogs. Hypertension Dallas 7: 253-261, 1985.
15. Horackova, M., and J. A. Armour. Role of peripheral autonomic neurons in maintaining adequate cardiac function. Cardiovasc. Res. 30: 326-335, 1995.
16. Horackova, M., M. H. Huang, J. A. Armour, D. A. Hopkins, and C. Mapplebeck. Cocultures of adult ventricular myocytes with stellate ganglia or intrinsic cardiac neurones from guinea pigs: spontaneous activity and pharmacological properties. Cardiovasc. Res. 27: 1101-1108, 1993.
17. Kem, D. C., E. I. M. Johnson, A. M. Capponi, D. Chardennens, U. Lang, B. Blondel, H. Koshida, and M. B. Vallotton. Effect of angiotensin II on cytosolic free calcium in neonatal rat cardiomyocytes. Am. J. Physiol. 261 (Cell Physiol. 30): C77-C85, 1991.
18. Kobayashi, M., Y. Furukawa, and S. Chiba. Positive chronotropic and inotropic effects of angiotensin II in the dog heart. Eur. J. Pharmacol. 50: 17-25, 1978.
19. Li, P., E. H. Sonnenblick, P. Anversa, and J. M. Capasso. Length-dependent modulation of ANG II inotropism in rat myocardium: effects of myocardial infarction. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H779-H786, 1994.
20. Lindpaintner, K., and D. Ganten. The cardiac renin-angiotensin system: an appraisal of present experimental and clinical evidence. Circ. Res. 68: 905-921, 1991.
21. Morita, H., J. Kimura, and M. Endoh. Angiotensin II activation of a chloride current in rabbit cardiac myocytes. J. Physiol. Lond. 483: 119-130, 1995.
22. Peach, M. J., and D. E. Dostal. The angiotensin II receptor and the actions of angiotensin II. J. Cardiovasc. Pharmacol. 16, Suppl 4: S25-S30, 1990.
23. Reid, I. A. Interactions between ANG II, sympathetic nervous system, and baroreceptor reflexes in regulation of blood pressure. Am. J. Physiol. 262 (Endocrinol Metab. 25): E763-E778, 1992.
24. Reid, I. A. Vasoactive peptides. In: Basic & Clinical Pharmacology (6th ed.), edited by G. G. Katzung. Norwalk, CT: Appleton & Lange, 1995, p. 276-289.
25. 1 receptors in the rat heart conduction system. Eur. J. Pharmacol. 235: 301-303, 1993.
26. Scroop, G. C., and R. D. Lowe. Central pressor effect of angiotensin mediated by the parasympathetic nervous system. Nature Lond. 220: 1331-1332, 1968.
27. Shapiro, M. S., L. P. Wollmuth, and B. Hille. Angiotensin II inhibits calcium and M current channels in rat sympathetic neurons via G proteins. Neuron 12: 1319-1329, 1994.
28. Steckelings, U. M., S. P. Bottari, and T. Unger. Angiotensin receptor subtypes in the brain. Trends Pharmacol. Sci. 13: 365-367, 1992.
29. 2 receptor-mediated chronotropic effect of bradykinin in isolated guinea pig atria. Eur. J. Pharmacol. 281: 17-20, 1995.
30. 2+ transients in neonatal and adult rat cardiomyocytes by angiotensin II and endothelin-1. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H857-H868, 1996.
31. Ziogas, J., D. F. Story, and M. J. Rando. Effects of locally generated angiotensin II on noradrenergic transmission in guinea-pig isolated atria. Eur. J. Pharmacol. 106: 11-18, 1985.